Tooth Development - Rougier Flashcards

(93 cards)

1
Q

Arch 1 is innervated by CN

A

V

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2
Q

arch 2 is innervated by CN

A

VII

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3
Q

During the _____ week of development thickenings of oral epithelium develop, overlying the future dental arches in the upper and lower jaws

A

6th

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4
Q

The dental lamina lies _______ (in coronal section) to the vestibular lamina; it has a horseshoe shape in its entirety

A

medial

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5
Q

The buds plus the closely-associated ectomesenchyme represent the primordia of the ________ teeth

A

deciduous

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6
Q

All the buds are present by the _____ week

A

8th

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7
Q

Development of cells that form dental tissues is the process of

A

histodifferentiation

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8
Q

At what month in development does the cap-like configuration

A

3rd

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9
Q

The cap-shaped epithelial proliferation is now identified as the _________ which has/forms what 4 things?

A

enamel organ

  1. inner enamel epithelium
  2. outer enamel epithelium
  3. SR
  4. SI
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10
Q

The enamel organ is _______ and lacks ________

A

avascular ; innervation

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11
Q

what is responsbile for formation of enamel

A

the enamel organ

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12
Q

the ______ is a condensation of ectomesenchymal tissue lying within the concavity of the enamel organ

A

dental papilla

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13
Q

once dentinogenesis is initiated, the dental papilla will become

A

vascularized and innervated

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14
Q

the cells of the dental papilla give rise to _____ and _____

A

dentin ; pulp

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15
Q

The ______ is a thickening of
ectomesenchymal tissue that encompasses the enamel
organ and dental papilla

A

dental follicle (or sac)

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16
Q

the dental follicle (sac) gives rise to what 3 things

A

cementum
PDL
alveolar bone

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17
Q

Cells of the inner enamel epithelium become tall
columnar cells. They are on their way to becoming
enamel-producing cells, the

A

ameloblasts

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18
Q

until production of enamel begins, you should actually view ameloblasts as what?

A

preameloblasts

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19
Q

In their preameloblast stage the inner enamel epithelial
cells induce neighboring ectomesenchymal cells of the
dental papilla to differentiate into dentin producing cells,
the ______

A

odontoblasts

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20
Q

we see development of the tooth buds for the permanent teeth, excluding the _____ in the _____ stage

A

molars ; bud

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21
Q

Because the molars don’t have decidious predecessors, the the tooth buds for permanent molars develop from

A

posterior extensions of the dental lamina

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22
Q

during the bell stage, the cells of the ____________ begin to degenerate. Over time,
this will create a furrow that forms the

A

vestibular lamina ; oral
vestibule

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23
Q

Dentinogenesis begins in the occlusal region of the future crown, where the newly differentiated odontoblasts produce

A

predentin

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24
Q

Predentin is the ___ matrix of dentin

A

organic

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25
Mineralization of predentin forms ____ which encloses the cytoplasmic process in a ______
dentin ; dentinal tubule
26
As the odontoblasts migrate centrally, a layer of predentin will ______ be present
always
27
enamel formation begins with mineralization of
dentin
28
preameloblasts are induced to complete their differentiation into ameloblasts by the presence of
mineralized dentin
29
The simultaneous formation of enamel and dentin is termed the _____ stage
appositional
30
As preameloblasts differentiate, they induce differentiation of _______ and _______
odontoblasts ; dentinogenesis
31
dentinogenesis induces completion of the differentiation of _______ and _______
ameloblasts ; amelogenesis
32
The dynamics of dentin and enamel formation are an example of
reciprocal induction
33
Once enamel formation achieves its definitive thickness the ameloblasts regress. They combine with the other layers of the enamel organ to form a protective cellular coating known as the
reduced enamel epithelium
34
Crown formation for deciduous teeth is completed during the year
first
35
The root of the tooth is comprised of
dentin
36
cells of the inner enamel epithelium will also induce differentiation of _____ for root formation
odontoblasts
37
neural crest cells migrate into the pharyngeal arches and mix with mesenchyme to produce ______ to help form teeth
ectomesenchyme
38
what is the embryonic period
fertilization through 8 weeks
39
Initiation is signaled by development of the
dental lamina
40
a thickening of oral epithelium overlying ectomesenchyme
dental lamina
41
the _________ segment gives rise to maxillary incisors
intermaxillary
42
what is the forerunner of the dental and vestibular lamina
the primary epithelial band
43
developmental origin of oral epithelium is
ectoderm
44
what line separates ectoderm from ectomesenchyme (which has NCCs)
the primary epithelial band
45
differentiation of the primary epithelial band proceeds differentiation of
ectomesenchyme
46
what are the 6 events associated with tooth development
Initiation Proliferation Morphogenesis Differentiation Apposition Eruption
47
what event associated with tooth development is: dental lamina formation
initation
48
what event associated with tooth development is: mitosis within dental lamina & ectomesenchyme to establish tooth primordium
proliferation
49
what event associated with tooth development is: changes of shape that lead to bud, cap, bell stages
Morphogenesis
50
what event associated with tooth development is: formation of ameloblasts & odontoblasts
Differentiation
51
what event associated with tooth development is: dentin & enamel formation
Apposition
52
what event associated with tooth development is: root formation
eruption
53
the vestibular lamina is ALWAYS ______ to the dental lamina
labial
54
formation of dental lamina is also mirrored by the 2nd folding that is labial to it and called a
vestibular lamina
55
a thickening of oral epithelium (derived from ectoderm)
dental lamina
56
change of the plane of cleavage in cells of the epithelial band is the origin of the
dental lamina
57
tooth buds are derived from
ectoderm
58
tooth bud formation happens during the __ to __ week of development
6th - 8th
59
_______ tissue releases factors that stimulate development of the tooth bud
Ectomesenchymal
60
The tooth bud becomes the enamel organ in the ____ stage
cap
61
the enamel organ has _____ origin
ectodermal
62
dental papilla is derived from ______ and "makes" ____ and _____
ectomesenchyme ; pulp ; dentin
63
dental follicle is derived from ______ and "makes" ____ , _____ , and _____
ectomesenchyme ; PDL ; cementum ; alveolar bone
64
The vestibular lamina lies ____ to the cap stage
lateral
65
the _______ is the beginning of all tooth cusps
enamel knot
66
the origin of all dental tissue is the
cervical loop
67
3 Important Events during the Bell Stage:
Configuration of the crown is determined a successional lamina is formed, with permanent tooth buds histodifferentiation: dentin and enamel formation will occur
68
formation of crown is determined during the _____ stage
bell
69
we have the beginning of our appositional stage during what stage
Bell
70
the sucessional lamina is always on the ____ side
lingual
71
during the late bell stage, the dental lamina will begin to atrophy internally and disconnect from the oral epithelium and develop a 2nd process called the
successional lamina
72
the successional lamina gives rise to
permanent dentition
73
10 primary teeth and 10 permanent teeth will develop in association with the initial
dental lamina
74
______ are first to mature and erupt
Incisors
75
Odontogenesis moves ______ as jaws develop and lengthen
posteriorly
76
In the bell stage, the configuration of the crown is determined in sites where _______ ceases and causes buckling of the _____
mitotic activity ; IEE
77
There is histodifferentiation of cells of the IEE and Outer Dental Papilla (ODP) in
future cuspal area
78
Cells of the IEE begin organizing to form
preameloblasts
79
cells in IEE secrete growth factor that secrete into cells of the outer dental papilla which causes them to differentiate into odontoblasts which secrete
dentin
80
ameloblasts secrete a ________ matrix which eventually becomes ______
non-mineralized ; mineralized
81
what is the only tissue with a non-mineralized precursor
enamel
82
_______ are the first cells to reach functional maturity
Odontoblasts
83
the location of future cuspal edge is found in what stage
bell stage
84
1st tissue secreted by odontoblasts is _______ and the 1st mineralized tissue they secrete is _________ which begins in the _____ until it reaches the ________ and the ______ and then it is complete
pre-dentin ; dentin ; cusp ; cervical loop ; crown
85
Appositional stage begins in _____ regions and progresses in a cervical direction
cuspal
86
The interface where enamel and dentin meet is termed the _____
DEJ
87
Ameloblasts move _____ from the DEJ as enamel is formed
away
88
Odontoblasts migrate _____ developing pulp
into
89
Dentin and enamel formation extend in a ______ direction
cervical
90
Enamel formation stops when it reaches the
cervical loop
91
the enamel organ has NO _________
blood supply
92
When the full thickness of the enamel is achieved, the layers of the enamel organ become compressed, forming the
reduced enamel epithelium
93
The REE also has as protective mechanism, separating the ______ from the _______
enamel ; ectomesenchyme