Top 300 BBW Flashcards

(114 cards)

1
Q

Alprazolam BBW

A

Concurrent use with opioids

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2
Q

Amiodarone BBW

A

Arrhythmias, hepatotoxicity, proarrhythmic effects, pulmonary toxicity

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3
Q

Amitriptyline BBW

A

Suicidality; not approved for children <12 y of age

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4
Q

Apixaban BBW

A

Premature discontinuation increases risk of thrombotic events; increased risk of spinal hematoma with spinal puncture or neuraxial anesthesia

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5
Q

Aripiprazole BBW

A

Dementia, suicidality

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6
Q

Atenolol BBW

A

Avoid abrupt withdrawal

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7
Q

Atomoxetine BBW

A

Suicidality in children and adolescents

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8
Q

Azathioprine BBW

A

Malignancy

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9
Q

Baclofen BBW

A

Avoid abrupt discontinuation of oral or intrathecal product

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10
Q

Benazepril BBW

A

Pregnancy, fetal toxicity

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11
Q

Budesonide/Formoterol BBW

A

Asthma deaths; pediatrics, increased risk of hospitalization

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12
Q

Bupropion BBW

A

Suicidality; neuropsychiatric reactions

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13
Q

Canagliflozin BBW

A

Lower limb amputation

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14
Q

Candesartan BBW

A

Pregnancy

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15
Q

Carbamazepine BBW

A

Agranulocytosis, aplastic anemia; dermatological reactions (especially in asians); screen for HLA-B*15:02

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16
Q

Celecoxib BBW

A

GI toxicity, cardiotoxicity, CABG

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17
Q

Ciprofloxacin BBW

A

May exacerbate muscle weakness in patients with myasthenia gravis, tendon inflammation and rupture, peripheral neuropathy, CNS effects, cardiac, dermatologic, and hypersensitivity reactions, aortic dissection and rupture, hypoglycemia, mental health adverse effects

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18
Q

Citalopram BBW

A

Suicidal ideation; not approved for use in children

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19
Q

Clindamycin BBW

A

Colitis

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20
Q

Clobazam BBW

A

Concurrent use with opioids, abuse and addition, dependence and withdrawal reactions

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21
Q

Clonazepam BBW

A

Concurrent use with opioids, abuse, misuse, addiction, dependence, and withdrawal reactions

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22
Q

Clonidine BBW

A

Epidural use

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23
Q

Clopidogrel BBW

A

Reduced CYP2C19 function

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24
Q

Codeine BBW

A

Hepatotoxicity; Children who are CYP2D6 ultrarapid metabolizers; serious risks of misuse, abuse, addiction, overdose, and death; concurrent use with benzodiazepines; immediate release only; serious risk of misuse, accidental ingestion, neonatal opioid withdrawal syndrome

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25
Conjugated Estrogens BBW
Breast cancer, cardiovascular disease, endometrial cancer, dementia risks
26
Dabigatran BBW
Use in elderly; risk of stroke at discontinuation; spinal epidural hematoma
27
Darbepoetin BBW
Increased CV, stroke, mortality risk; cancer recurrence
28
Desvenlafaxine BBW
Suicidality; not for use in children; not for bipolar disorder
29
Dexmethylphenidate BBW
Tolerance and dependence
30
Diazepam BBW
Concurrent use with opioids
31
Diclofenac BBW
Cardiovascular, GI risk, CABG
32
Divalproex BBW
Hepatotoxicity, teratogenicity, pancreatitis
33
Doxepin BBW
Suicidality
34
Dulaglutide BBW
Risk of thyroid cancers
35
Duloxetine BBW
Suicidality; not approved for children
36
Edoxaban BBW
Premature discontinuation increases risk of thrombotic events; increased risk of spinal hematoma with spinal puncture or neuraxial anesthesia; reduced efficacy in nonvalvular atrial fibrillation patients with CrCl >95 mL/min
37
Febuxostat BBW
Increased risk of death (cardiac, all-cause)
38
Fentanyl BBW
CYP3A4/5 inhibitors; respiratory depression; transdermal not for use postoperatively; fatalities in children; formulations not interchangeable; fever; care with disposal; REMS program; concurrent use with benzodiazepines or other CNS depressants
39
Fluoxetine BBW
Suicidality; approved in children >7 years of age
40
Fluticasone/Salmeterol BBW
Increased asthma-related deaths
41
Fosinopril BBW
Pregnancy
42
Furosemide BBW
Fluid and electrolyte loss
43
Hydrocodone BBW
Addiction, abuse, misuse, REMS, respiratory depression, accidental ingestion, neonatal opioid withdrawal, alcohol, CYP3A4/5 interactions, hepatotoxicity, concurrent use with benzodiazepines
44
Ibuprofen BBW
Cardiovascular events, GI toxicity, CABG
45
Indomethacin BBW
Cardiovascular events, GI toxicity, CABG
46
Insulin BBW
Risk of acute bronchospasm with inhaled formulation
47
Irbesartan BBW
Pregnancy
48
Lamotrigine BBW
Serious skin reactions
49
Levofloxacin BBW
Myasthenia gravis, tendon inflammation and rupture, peripheral neuropathy, CNS effects, cardiac, dermatologic and hypersensitivity reactions, aortic dissections and ruptures
50
Levothyroxine BBW
Not for weight reduction
51
Liraglutide BBW
Increased risk of thyroid cancer
52
Lisdexamfetamine BBW
Risk of abuse, misuse, diversion
53
Lisinopril BBW
Pregnancy
54
Lithium BBW
Lithium levels required
55
Lorazepam BBW
Concurrent use with opioids
56
Losartan BBW
Pregnancy
57
Lurasidone BBW
Dementia, suicidality
58
Maraviroc BBW
Hepatotoxicity, severe rash, allergic reaction
59
Medroxyprogesterone BBW
Cardiovascular, dementia risk, loss of BMD (Depo-Provera); breast cancer
60
Meloxicam BBW
Cardiovascular thrombotic events, serious GI bleeding and perforation, CABG
61
Metformin BBW
Lactic acidosis
62
Methadone BBW
Accidental ingestion; addiction, abuse, and misuse; QTc prolongation; respiratory depression; concurrent use with benzodiazepines; REMS; neonatal opioid withdrawal; conditions for use in opioid addiction; CYP interactions
63
Methotrexate BBW
Bone marrow suppression, renal impairment, hepatotoxicity, pneumonitis, GI toxicity, secondary malignancy, tumor lysis syndrome, dermatologic toxicity, opportunistic infections, radiotherapy
64
Methylphenidate BBW
Abuse and dependence potential
65
Metoclopramide BBW
Tardive dyskinesia
66
Metoprolol BBW
Ischemic heart disease with abrupt withdrawal
67
Metronidazole BBW
Carcinogenic
68
Mirtazapine BBW
Suicidality; not for use in children
69
Morphine BBW
Ethanol, addiction, abuse, and misuse, REMS, respiratory depression, neonatal opioid withdrawal, accidental ingestion, concurrent use with benzodiazepines, medication errors
70
Moxifloxacin BBW
Myasthenia gravis, tendon inflammation and rupture peripheral neuropathy, aortic dissections, hypoglycemia, delirium
71
Nabumetone BBW
Thrombotic events, GI bleeding
72
Naproxen BBW
Cardiovascular and GI risk, thrombotic events
73
Nortriptyline BBW
Suicidality
74
Olanzapine BBW
mortality in elderly patients with dementia-related psychosis; DRESS
75
Olmesartan BBW
Pregnancy
76
Oxycodone BBW
Addiction, abuse potential; REMS, respiratory depression, accidental ingestion, neonatal withdrawal, CYP3A4/5 interaction, concurrent use with benzodiazepines, medication errors with oral solution
77
Paroxetine BBW
Suicidality
78
Phenytoin BBW
Hypotension and arrhythmias with IV administration
79
Pioglitazone BBW
Heart failure risk
80
Prasugrel BBW
Bleeding risk, not recommended in patients >/= 75 years of age, CABG
81
Prenatal vitamin BBW
Iron toxicity
82
Prochlorperazine BBW
Mortality in elderly with dementia
83
Progesterone BBW
Cardiovascular disorders, breast cancer, dementia risk, risk versus benefits
84
Promethazine BBW
Children <2 y (fatal respiratory depression)
85
Propranolol BBW
Avoid abrupt withdrawal
86
Quetiapine BBW
Mortality in elderly with dementia, suicidality, not approved for children <10 y
87
Quinapril BBW
Pregnancy
88
Raloxifene BBW
Venous thromboembolism, stroke
89
Ramipril BBW
Pregnancy
90
Risperidone BBW
Mortality in elderly with dementia, DRESS
91
Rivaroxaban BBW
Premature discontinuation increases thrombotic risk, risk of spinal/epidural hematoma
92
Rosiglitazone BBW
Heart failure, MI risk
93
Sacubitril/Valsartan BBW
Pregnancy
94
Sertraline BBW
Suicidality, not approved for depression in children, approved for OCD in children >6 y
95
Sofosbuvir BBW
HBV reactivation
96
Spironolactone BBW
Tumorigenic in animal models
97
Tacrolimus BBW
Risk of infection, risk of malignancies, increased mortality in female transplant patients with Astagraf XL, Astagraf XL not approved for liver transplant
98
Tamoxifen BBW
Uterine malignancies, stroke, pulmonary embolism
99
Telmisartan BBW
Pregnancy
100
Temazepam BBW
Concurrent use with opioids
101
Testosterone BBW
Secondary exposure
102
Thyroid BBW
Ineffective and potentially toxic when used for weight loss
103
Ticagrelor BBW
Bleeding risk, use in CABG surgery, avoid aspirin >100 daily
104
Tolvaptan BBW
Initiate treatment in hospital to monitor serum sodium. Too rapid correction (eg, >12 mEq/24hr) can result in seizures, coma, and death; correct sodium gradually.
105
Tramadol BBW
Addiction, abuse, misuse, REMS, respiratory depression, accidental ingestions, CYP2D6, neonatal withdrawal syndrome, drug interactions, concurrent benzodiazepines, errors
106
Trazodone BBW
Suicidal ideation, not for use in children
107
Triamterene/Hydrochlorothiazide BBW
Hyperkalemia
108
Triazolam BBW
Concurrent use with opioids
109
Valsartan BBW
Pregnancy
110
Venlafaxine BBW
Suicidal Ideation
111
Vilazodone BBW
Suicidal thinking and suicidal behavior
112
Warfarin BBW
Bleeding
113
Ziprasidone BBW
Elderly patients with dementia are at increased risk of death, DRESS
114
Zolpidem BBW
Risk of complex sleep behaviors (sleepwalking, sleep driving, etc.)