Top 300 indications Flashcards
(162 cards)
Acyclovir indications and dosing
1.) Genital herpes simplex:
Adults, initial episode-
400 mg TID x7-10 days
200 mg PO 5x daily x 7-10 days
Adults, recurrent-
400 mg TID x 5 days
800 mg BID x 5 days
800 mg TID x 2 days
2.) Genital herpes simplex, suppressive therapy:
Adults and children >/= 12 years old: 400 mg BID for up to 12 months
3.) Herpes zoster (shingles):
Adults and children >/= 12 years old: 800 mg 5x daily for 7-10 days
4.) Varicella (chickenpox):
Adults- 800 mg po 5 x daily x 5-7 days
5.) Cold sores (orolabial HSV treatment): 400 mg PO TID x 5-10 days
Adapalene indications and dosing
1.) Acne vulgaris:
Adults and children >12 yo, apply thin film topically to affected area(s) daily hs
Albendazole indications and dosing
1.) Parenchymal neurocysticercosis caused by Taenia solium, cystic hydatid disease of the liver, lung, and peritoneum caused by Echinococcus granulosus:
Adults >/= 60 kg- 400 mg PO BID with meals x 8-30 days
Adults and children <60 kg: 15mg/kg/day (max 800mg/day) in 2 divided doses x 8-30 days
Albuterol indications and dosing
1.) Asthma (acute exacerbation):
Adults, MDI, 4-8 inhalations every 20 min up to 4 h, then every 1-4 h prn
Children, 4-8 inhalations every 20 min for 3 doses, then every 1-4 h prn (use mask for children <4 y of age)
2.)Asthma (bronchospasm):
Adults and Children, MDI/dry powder inhalation, 2 inhalations every 4-6 h prn
Adults and Children ≥12 y of age, oral, 2-4 mg immediate-release tablet po tid or qid or 4-8 mg extended release tablet po q12h (max 32 mg/d)
3.) Exercise-induced asthma, prevention:
Adults, MDI/dry powder inhalation, 2 inhalations 15-30 min prior to exercise
4.) Chronic obstructive pulmonary disease (acute symptom relief): MDI/dry powder inhalation, 2 inhalations every 4-6 h prn
5.) Chronic obstructive pulmonary disease (acute exacerbation): MDI/dry powder inhalation, 1-8 inhalations every 1-4 h prn
Alendronate indications and dosing
1.) Postmenopausal osteoporosis, prophylaxis: 5 mg po daily or 35 mg po once weekly
2.) Postmenopausal osteoporosis, treatment: 10 mg po daily or 70 mg po once weekly
3.) Osteoporosis, treatment, male: 10 mg once daily or 70 mg po once weekly
4.) Glucocorticoid-induced osteoporosis in those with daily dosage ≥7.5 mg of prednisone (or equivalent) treatment: 10 mg po once daily or 70 mg po once weekly
5.) Paget disease: 40 mg po daily for 6 mo
6.) Osteoporosis, prophylaxis, male: 5 mg po once daily or 35 mg po once weekly
Allopurinol indications and dosing
1.) Gout, mild: 100-300 mg po daily; max dose 800 mg/d
2.) Gout, moderate to severe: 400-600 mg po daily in 2-3 divided doses, max dose 800 mg/d
3.) Hyperuricemia, tumor lysis syndrome: Children <6 y, 50 mg po tid or 150 mg po daily for 2-3 d; Children 6-10 y, 100 mg po tid or 300 mg po daily for 2-3 d; Adults, 600-800 mg/d po daily in 2-3 divided doses for 2-3 d; starting 12 h-3 d prior to chemotherapy
4.) Nephrolithiasis prophylaxis due to calcium stones: 300 mg/d divided in 1-3 doses
Alprazolam indications and dosing
1.) Anxiety: immediate-release, orally disintegrating tablet or solution, 0.25-0.5 mg po tid; max daily dose, 4 mg in divided doses
2.) Panic disorder, with or without agoraphobia: immediate-release or orally disintegrating tablets, 0.5 mg po tid, extended release 3-6 mg po daily; dose may be increased every 3-4 d by <1 mg/d
Amiodarone indications and dosing
Secondary prophylaxis of ventricular arrhythmias: 400 mg po q8-12h × 1-2 wk, then 200-400 mg po once daily or 400 mg po q8-24h for a total load of 6-10 g, then 200-400 mg po once daily
Amitriptyline indications and dosing
Depression: Adults, 75 mg po divided into 1-3 daily doses, titrate to max 300 mg/d; Children ≥12 y of age, 10 mg po tid or 20 mg po daily hs
Amlodipine indications and dosing
1.) HTN: Children 6-17 y of age, 2.5-5 mg po daily; Adults, 5-10 mg po daily
2.) Stable angina: 5-10 mg po daily
3.) Variant angina: 5-10 mg po daily
Amoxicillin indications and dosing
1.) Acute otitis media: Adults, 500 mg q8h or 875 mg po q12h × 10 d; Children, 80-90 mg/kg/d po in 2-3 divided doses
2.) Lower respiratory tract infection: Adults, 1 g po tid × 10 d; Children, 45 mg/kg/d divided q12h
3.) Pharyngitis, tonsillitis: Adults and Children >12 y, 775 mg po daily × 10 d
4.) Streptococcal pharyngitis: Adults, 500 mg po bid or 1 g po daily × 10 d; Children, 50 mg/kg po once daily for 10 d, max 1 g daily
5.) Ear, nose, and throat infection, infection of skin and/or subcutaneous tissue, infection of genitourinary system: Adults, 500 mg po q8h or 875 mg po q12h × 5-10 d; Children, 25-45 mg/kg/d po divided q12h
6.) H. pylori GI tract infection: 1 g po bid with PPI
Amoxicillin/clavulanate indications and dosing
1.) Acute otitis media: Adults, 500-875 mg po q12h × 10 d; Children, 80-90 mg/kg/d po in 2-3 divided doses
2.) Community-acquired pneumonia: Adults, 2000 mg extended release po bid or 500 mg po tid or 875 mg po bid × 5 d
3.) Lower respiratory tract infection: Adults, 1000 mg po tid × 10 d; Children, 45 mg/kg/d po divided q12h
4.) Sinusitis, infection of skin or subcutaneous tissue, infectious disease of genitourinary system: Adults, 500-875 mg po q8-12h or 2000 mg extended release po q12h × 5-7 d; Children, 25-45 mg/kg/d po divided q12h
5.) Urinary tract infection, acute cystitis: 500 mg po bid × 5-7 d
6.) Urinary tract infection, pyelonephritis: 875 mg po bid × 10-14 d
Anastrazole indications and dosing
1.) Breast cancer, adjuvant, postmenopausal, hormone receptor-positive: 1 mg po daily × 5 y (or × 10 y when used in combination with tamoxifen)
2.) Breast cancer, advanced or metastatic, postmenopausal, following tamoxifen therapy: 1 mg po daily, until tumor progression
Apixaban indications and dosing
1.) Atrial fibrillation, nonvalvular (prophylaxis, to reduce the risk of stroke): 5 mg po bid
2.) Hip or knee replacement surgery (prophylaxis, to reduce the risk of DVT and PE): 2.5 mg po bid × 12 d (knee replacement) or 35 d (hip replacement); start 12-24 h postoperatively
3.) DVT or PE (treatment and to reduce the future risk): 10 mg po bid × 7 d, then 5 mg po bid
Aripiprazole indications and dosing
1.) Bipolar disorder, manic or mixed episodes, acute treatment: Adults, 10-15 mg po daily, may titrate to 15-30 mg po daily; Children >10 y, 2 mg po daily, may titrate to 10 mg po daily
2.) Schizophrenia: Adults, 10-15 mg po daily, may titrate to max 30 mg/d; Children >13 y, 2 mg po daily, may titrate to 10 mg po daily
3.) Depression, adjunctive with antidepressant: 2-4 mg po daily, may titrate to 15 mg po daily
4.) Tourette syndrome: Children ≥6 y of age and <50 kg, 2 mg po daily, may titrate to 5-10 mg po daily; Children ≥6 y of age and ≥50 kg, 2 mg po daily, may titrate to 10-20 mg po daily
5.) Irritability with autistic disorder: Children ≥6 y of age, 2 mg po daily × 7 d, then 5 mg po daily, may titrate to 15 mg/d
Atazanavir indications and dosing
1.) Treatment of HIV-1 infection, antiretroviral-naïve: Adults and Children ≥13 y of age and ≥40 kg, 300 mg po daily with ritonavir 100 mg or cobicistat 150 mg; Adults unable to tolerate ritonavir, atazanavir 400 mg daily (ritonavir unboosted regimen not recommended in children)
2.) Treatment of HIV-1 infection, patients with prior virologic failure: Adults and Children ≥13 y of age and ≥40 kg, 300 mg po daily with ritonavir 100 mg or cobicistat (monotherapy with atazanavir not recommended); Children <13 y of age, weight based and used in combination with ritonavir
3.) Treatment of HIV-1 infection in pregnant patients, antiretroviral-naïve or experienced: 300 mg po daily with ritonavir 100 mg po daily
Atenolol indications and dosing
1.) Angina pectoris, chronic: 50 mg po daily; titrate to 100-200 mg po daily
2.) HTN: Adults, 50 mg po daily, titrate to 100 mg po daily; Children, 0.5-1 mg/kg/d po in 1-2 divided doses, titrate to 2 mg/kg/d po in 1-2 divided doses (max 100 mg/d)
3.) AMI: 25-50 mg po bid (max 100 mg/d in 1-2 divided doses
Atomoxetine indications and dosing
ADHD: Children >6 y of age and weighing ≤70 kg, 0.5 mg/kg/d po, may titrate to lower of 1.4 mg/kg/d or 100 mg/d; Children >6 y of age and weighing >70 kg, 40 mg/d po, may titrate to 100 mg/d; Adults, 40 mg po daily, may titrate to 100 mg/d
Atorvastatin indications and dosing
1.) Hyperlipidemia: 10-20 mg po daily, may increase to 80 mg po daily
2.) Primary and secondary prevention of atherosclerotic cardiovascular disease: 10-20 mg po daily, may increase to 80 mg po daily for those patients requiring high-intensity therapy (eg, LDL >190 mg/dL or high ASCVD risk)
3.) Secondary prevention of cardiovascular events in patients with or at high risk for CAD: 80 mg daily, may reduce dose to 40 mg po daily if high dose not tolerated
4.) Familial hypercholesterolemia (homozygous): Children (boys and postmenarchal girls 10-17 y of age), 10 mg po daily, may titrate to 40 mg po daily; Adults, 10-80 mg po daily
Azathioprine indications and dosing
1.) Renal transplantation: Adults, 3-5 mg/kg/d po immediately after the transplant, then 1-3 mg/kg po daily
2.) Rheumatoid arthritis: Adults, 1-2.5 mg/kg/d po either once daily or divided bid
Azelastine indications and dosing
1.) Perennial allergic rhinitis: Adults and Children ≥12 y of age, 2 sprays per nostril bid; Children 6-12 y of age, 1 spray per nostril bid
2.) Seasonal allergic rhinitis: Adults and Children ≥12 y of age, 1-2 sprays per nostril bid; Children 6-12 y of age, 1 spray per nostril bid
3.) Vasomotor rhinitis: Adults and Children ≥12 y of age, 2 sprays per nostril bid
Azithromycin indications and dosing
1.) Acute infective exacerbation of COPD, skin or tissue infection: 500mg po daily × 3 d or 500 mg po × 1 dose, then 250 mg po daily × 2-5 d
2.) Bacterial sinusitis: Adults, 500 mg po daily × 3 d; Children, 10 mg/kg po daily × 3 d, or 2 g po × 1 dose
3.) Chancroid, nongonococcal cervicitis, nongonococcal urethritis: 1 g po × 1 dose
4.) Community-acquired pneumonia: 500 mg po daily × 3 d or 500 mg po × 1 dose, then 250 mg po daily × 2-5 d; Infants ≥6 mo of age, tablets and oral suspension, 10 mg/kg po on day 1, then 5 mg/kg po daily × 2-5 d or oral suspension, <34 kg, 60 mg /kg po × 1 dose;>34 kg, 2 g po × 1 dose
5.) Sexually transmitted infections: 1-2 g po × 1 dose
6.) Streptococcal pharyngitis: 500 mg po × 1 dose, then 250 mg po daily × 2-5 d; Children, 12 mg/kg po daily × 5 d
Baclofen Indications and Dosing
1.) Spasticity: 5 mg TID
Benazepril indications and dosing
1.) Hypertension: 10 mg QD