Top Drugs 2019 Flashcards

(577 cards)

1
Q

Donezepril

A

Aricept
Anti cholinesterase
For dementia / Alzheimer’s

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2
Q

Vorapaxar

A

Zontivity
Par-1 inhibitor
With low dose aspirin and - or Clopidogrel for secondary prevention of post mi or pad

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3
Q

Verelan

A

Verapamil

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4
Q

Plavix

A

Clopidogrel

Irreversibly blocks p2y12

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5
Q

Risk

A
= (# patients unfavorable event)/
# in group
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6
Q

Latanoprost

A

Xalatan

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7
Q

Activase

A

Thrombolytic
Tpa
Produces fibrinolysis

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8
Q

Pristiq.

A

Devenslafaxine

SNRI

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9
Q

Exforge

A

Amlodipine/Valsartan

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10
Q

Dilt-XR

A

Diltiazem

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11
Q

Azilsartan

A

Edarbi.

ARB

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12
Q

Clopidogrel

A
Plavix
Irreversible p2y12
Loading dose 300-600 mg then 75 mg PO we’d
Cyp2c19 enzymes convert to prodrug
D/c 5 days prior to surgery
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13
Q

Hydrocortisone, topical

A

Cory’s is

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14
Q

AScVD risk patients >= 20%

A

Who do not achieve ldl <= 70%

Add ezetimibe with statin

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15
Q

Inhaled corticosteroids

A

Beclomethasone (QVAR)
Budesonide (Pulmicort flexhaler)
Fluticasone ( Flovent HFA)

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16
Q

Interferon 1b

Betaseron. Extavia.

A

Room temp
SQ every other day
Flu like symptoms

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17
Q

Diazepam

A

Valium

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18
Q

Ariprazole

A

Ability

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19
Q

Methotrexate

A

Trexall
MOA: inhibits dihydrofolic acid
Inhibits purine and thymidyl acid
Interferes with DNA synthesis repair and cellular respiration S phase

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20
Q

Fluticasone

A

Flovent HFA, Flovent discus, Arnuity Elliott, Armonair respiclick

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21
Q

Twynsta

A

Amlodipine & telmisartan

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22
Q

Ocrelizumab

A

Ocrevus

Once every 6 mos.

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23
Q

Tiazac

A

Diltiazem

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24
Q

Evolocumab

A

Repatha.
Dec ldl
Psk9 inhibitors

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25
Formoterol & mometasone
Dulera
26
Prestalia
Amlodipine & perindopril
27
Dolasetron
Anzemet | Anti emetic
28
Ca carbonate | Ca citrate
Ca carbonate .40 elemental Ca | Ca citrate.21 elemental iron
29
Folic acid
Vitamin B9
30
Dexamethasone
De pal
31
Lisinopril
Prinivil, Zestril,Qbrelis oral solution
32
Anti coagulants
Prevent fibrin formation | Glue between platelets
33
Colestipol
Coke stud Bile acid sequestant Dec ldl
34
Atorvastatin
Lipitor
35
Estradiol patch
Vivelle dot Alora. Climara Estrogen
36
Silodosin
Rapaflo | Bph
37
Methylphenidate
Medrol MOA: unknown May block reuptake Norepinephrine & Dopamine into presumptive neurons
38
Losartan/HCTZ
Hyzaar
39
Duloxetine
Cymbalta SNRI Anti-depressant
40
Doxepin
Silenor. | TCA.
41
Albuterol
Proair hfa, proair respiclick, Proventil hfa, Ventolin hfa
42
Dypyridamole
Persantine. | Reversible inhibitor of platlet aggregation vasodilator
43
Ziac
Bisoprolol/HCTZ
44
Irbesartan
Avapro | ARB
45
Adenosine
Adenocard pSVt T 1/2 <10 seconds
46
Ciclesonide
Alvesco Prodrug MSU solution Don’t shake
47
Olopatadine
Pataday/ patanol. | Antihistamines ophthalmic
48
Benazepril
Lotensin
49
Ciprofloxacin
Cipro
50
Formoterol /Budesonide
Symbicort
51
Teriflunomide
``` Aubagio PO QD Ms Preg. Cat X Hepatotoxic ```
52
Buprenorphine/Naloxone
Suboxone (SL film) Bunavail (buccal film) Zubsolv (SL tablet)
53
Premarin, conjugated
Premarin
54
Doxazosin
Cardura. | Bph & HTN
55
Argatroban.
Direct thrombin inhibitor
56
Mupirocin, topical
Bactroban
57
Simvastatin
Zocor | Ezetimibe & Simvastatin (Vytorin)
58
Losartan
Cozaar | ARB
59
Candesartan
Atacand | Arb
60
GoNitro
Nitroglycerin sublingual powder | GoNitro
61
Fluticasone propionate
Flonase allergy relief | Veramyst
62
Doxycyclomine
Ventolin
63
Fluticasone furoate/ Vilanterol
Breo. ellipta. | LABA
64
Ipratropium & Albuterol
Nebulized solution | Duoneb
65
Entresto
Sacubitril. &. valsartan
66
Buspirone
Buspar | Anti anxiety
67
Duragesic
Fentanyl patch
68
Diohenoxylate/Atropine
Lomotil
69
Vasotec
Enalapril
70
Escitalopram
Lexapro SSRI Anti depressant
71
Ezetimibe
Zetia. | Inhibits cholesterol absorption from intestinal brush border
72
Flovent
Fluticasone inhaler
73
Liraglutide
Victoza, ,Saxenda | Analog GLP-1 increases insulin secretion due to elevated glucose
74
Ezetimibe & Simvastatin
Vytorin
75
Insulin Lispro
Humalog | Humalog kwickpen
76
Insulin Detemir
Levemir, Levemir flextouch
77
Omega-3-acid
Lovaza | Fish oil epa/DHA
78
Doxazosin Ext Release
Carders xl | Bph only
79
Montelukast
Singulair | Anti leukotriene
80
Fenofibrate
PPAR alpha activators | Decrease Tgk
81
Acetaminophen/codeine
Tylenol #2,#3, #4
82
Sildenafil
Viagra | Revatio. PAH
83
Cymbalta
Duloxetine | SNRI
84
Lotrel
Amlodipine & benazepril
85
Ivabradine
Corlanor Stable resting HR > 70 bpm Systolic HF
86
Atomoxetene
Strateera.
87
Fenoldopam
Corlopam | Good for renal HTN emergency
88
Clonazepam
Klonopin
89
Exforge
Amlodipine & valsartan
90
Levetiracetam
Keppra
91
Nitrostat
Nitroglycerin sublingual
92
Methylprednisolone
Medrol | MOA: potent glucocorticoid.
93
Liptruzet
Atorvastatin & ezetimibe
94
Diltiazem
Cardizem,cardizem cd, cardizem la, cartia XT, tiazac
95
Vardenafil
Levitra. | Staxyn-ODT
96
Asamex
Mometasone
97
Cardiogenic. Shock
Dobutamine
98
Revefenacin
Yupeiri | QD nebulizer
99
Integrillin
Eptibatide Anti platelet. Blocks binding of fibrinogen - glycoproteins 2b/3a
100
Betrixaban
Bevyxxa VTE prophylaxis XA inhibitor
101
Felodipine
Plendil XR QD
102
Propranolol
Inderal
103
Bosentan
Tracleer | Pulmonary artery HTN
104
Insulin Glargine
Lantus, lantus solostar , to undo solostar
105
Salmeterol & fluticasone
Airduo respiclick
106
Epinephrine
Epipen. Epipen Jr. , Adrenaclick. 0. 3 mg/0.3 ml 0. 15 mg/ 0.15 ml
107
Ivabridine
Corlanor Selective sinus node inhibitor Slows HR without causing drop in BP
108
Metoprolol succinate ER
Toprol XR
109
Terazosin
Hytrin | BPH & HTN
110
RR | Relative risk
(Risk in Trt Grp)/(Risk in Control Grp)
111
Milrinone
Primacor IV Ionotropic class iii & IV + ionotrope and vasodilator
112
Celecoxib
Celebrex
113
Exforge
Amlodipine & Valsartan
114
Prazosin
Minipress HTN only | Alpha-1 blocker
115
Bromphenitamine Pseudoephedrine Dextromethorphan
Bromfed DM
116
Epoprostenol
Flolan IV Treprostinil (tivaso! IV, SC, PO, inhalation) Dilated pulmonary arteries & helps prevent blood clots Inhibit platlet function
117
Nesititide
Nature or
118
Bivalrudin
Direct thrombin inhibitor
119
Ipratropium
Atrovent hfa QID
120
Ambrisenten
Letairis! Oral Birth defects
121
Benzonatate
Tessalon Perles
122
Metoprolol succinate
Topril xL
123
Naproxen high dose
N/a
124
Alrmtuzumab
Lemtrada Relapsing MS IV IV 5 consecutive days year 1 IV 3 consecutive days year 2
125
Fluoxetine
Prozac, Saracen Major depressive disorder OCD SSRI
126
CI includes 1
Not statistically significant
127
Ezetimibe
Zetia. | Inhibits cholesterol absorption in small intestine
128
Edoxaban
Savaysa No if crcl > 95 ml/min XA inhibitor
129
Mitroxantrone
IV Lifetime dose 140 mg/m**2 Cardiac s/E
130
Cytomel
Synthetic thyroid hormone | Liothyronine
131
LABA | Long acting beta agonist
Salmeterol (Serevent discus) | Both asthma and cops
132
Tasting XT
Diltiazem
133
Patients benefit high intensity statin?
High intensity statin LDL >=190 mg/dL Or AScVD risk > 20%
134
Salmeterol & fluticasone
Advair LABA & steroid 100/50, 250/50, 500/50 No changes is steroid
135
Icosapent ethyl
Vascepa | Fish oil
136
Lotrel
Amlodipine/benezepril
137
Azithromycin
Zithromax Azithromax Z-pak Zmax
138
Reopro
Abciximab | 2b/3a
139
Enalapril
Vasotec, epaned IV
140
Lamotrigine
Lamictal, lamictal odt, lamictal starter kit
141
Bimatoprost
Lumigan, Latisse | Antiglacoma
142
Acludinium
Tur Diaz pressair Bid Dry powder inhaler
143
Merperidine
Demerol | 50-150 mg IM/Sq/PO q 3-4 hrs
144
Albuterol/Ipratropium
Combivent Respimat Albuterol beta 2 agonist bronchodilator Ipratropium anitcholinergic
145
LAMA | Long acting muscarinic antagonist
Tiotropium Spiriva respimat asthma Spiriva handihaler respimat cops
146
Amturnide
Amlodipine aliskiren HCTZ
147
Abciximab
``` IV Reopro Mouse antibody Gp2b3a Adjunct to pci Must use filter do not shake vial No renal adjustments needed ```
148
Nortriptyline
Pamelor. | TcA
149
Penbutolol
Levatol
150
Cartelolol
Ophthalmic only | Beta blocker
151
RCT | Randomized control trial
Compares experimental treatment to control [placebp]
152
Eszopiclone
Lunesta
153
Alirocumab
Praluent sq psk9 inhibitors | Dec ldl
154
Nystatin
Bio-Statin
155
Empaglifloxin
Jardiance | SGLT2 inhibitors
156
Betaxolol
Kerlone Ophthalmic Betoptic-S Beta blocker
157
Alvesco
Ciclesonide
158
Estradiol topical/ring
Estrace Earring Vagifem
159
Nifedipine
Procardia xl, adalat cc
160
Ca corrected
= Ca serum + [(4- Albumin) * 0.8]
161
Diltiazem
Cardizem, Tiazac
162
BIdIL
Hydralazine & isorbide dinitrate TiD
163
Insulin Aspart
Novolog | Novolog Pen
164
Nitroglycerin
Nitrostat, Nitrolingual, NitroMist
165
Benztropine
Cogentin Anti Parkinson’s Anticholinergic
166
Telmisartan
Micardis | ARB
167
Gemfibrozil
Lipid Decreased fatty acid uptake hepatic Increases HDL.
168
HCTZ
Microzide
169
Nicardipine
Cardene IV
170
Sotolol
Betapace
171
Lovenox
1 mg/kg SQ q12 or 1.5 mg/kg we
172
Lorazepam
Ativan Benzodiazepine Increases GABA inhibitor neurotransmitter
173
Alfuzosin ext release
Uroxatral | Bph
174
Digoxin levels
A fib 0.8 - 2.0 | CHF 0.5 - 0.8
175
Triamterene/HCTZ
Maxzide/Maczide 25,Dyazide
176
Budesonide
Pulmicort respules
177
Butalbital/acetaminophen/ caffeine
Fioricet
178
Bisoprolol
Zebeta | Beta blocker
179
Nitrofurantoin
Macrobid, Macrodantin
180
Inducers
``` Phenytoin Smoking Phenobarbitals Oxcarbezapine Rifampin Carmezapinr St. John’s wart ``` Psporcs
181
Docusate
Colace
182
Tadalafil
Cialis | Adcirca. pAH
183
Hydromorphone
Dilaudid
184
Ipratropium & Albuterol
Combivent respimat
185
Antiplatelets
Prevent platlet. Aggregation
186
Ethinyl estradiol/ norethinddrone FE
Junel. Loestrin
187
Losartan/HCTZ
Hyzaar
188
Digoxin
Digital, Lanoxin
189
Amiodarone
Pacerone
190
Methadone
dolophine. Narcotic agonist-analgesic of opiate receptors; inhibits ascending pain pathways, thus altering perception and response to pain; produces analgesia, respiratory depression, and sedation
191
Mirtazapine
Remeron,remeron Zoltan MOA: tetracyclic structure different than SSRIs TCAs MAOIS THRU ITS CENTRAL PRESYNATIC ALPha 2 adrenergic antagonist effects Stimulates norepi, seretonin release Indications: major depressive disorder Off label insomnia
192
Fenofibrate
Fibrin acid derivative | Lower TG
193
Linaclotide
Linzess. Irritable bowel syndrome Chronic idiopathic constipation
194
Isradipine bid
Dynacirc
195
Citalopram
Celexa
196
Olmesartan
Benicar | ARB
197
Avanafil
Stendra.
198
Nadolol
Corgard
199
Salmeterol
Serevent | LABA
200
Sildenafil
Viagra, Revatio (PAH) | Thanks again
201
Nisoldipine
Sular | Extended release tabs
202
Levocetirizine
Xyzal
203
Medroxyprogesterone
Provera. Amenorrhea Contraception Endometrial hyperplasia
204
Amlodipine
Norvasc
205
Zafirlukast
Accolate | Anti-leukotriene
206
Carbidopa/levodopa
Sinemet
207
Ramipril
Altace only caps
208
Ofloxacin.
Ocuflox Fluroquinolone Inhibits DNA guarded Inhibits transcriptions
209
Brillinta
Titagrelor | P2y12
210
Fondaparinux
Arixtra No if Crcl < 30 ml/min Indirect XA inhibitor
211
Fluvastatin
Lescol(generic)
212
Clarithromycin
Biaxin
213
Hydrocodone/Acetaminophen
Portable, Lorcet, Norco, Vicodin
214
Atenolol
Tenormin | Beta blocker
215
Neomycin/polymyxin/dexamethasone
Maxitrol MOA: inhibits protein synthesis by binding to 30S ribosomal subunits Ophthalmic susp/oint for bacterial eye infection
216
Losartan
Cozaar | ARB
217
Eprosartan
Teveten | ARB
218
Factorial design
> 2 groups Randomizes to more than usual 2 groups to test experimental conditions.
219
Digoxin
Lanoxin, lanoxicaps, digital + ionotrope - chronotropic
220
Apixaban
Eloquis
221
Eptifibatide
Integrillin Acute coronary syndrome PCI with or without stents IIb/3A
222
Loratadine
Claritin 2nd gen antihistamine Selective H1 antagonist activity
223
Isosorbide dinitrate Isordil titradose Bid,tid
7 am, noon, 5 pm | Nitrate free interval >= 14 hours
224
Anion gap
Na. - CL. - HCO3
225
Dulaglutide
Trulicity
226
Atenolol
Tenormin
227
Zileuton
Zyflo, Zyflo CR | 5-lipoxygenase inhibitor
228
Hyzaar
Losartan & Hydrochlorothiazide
229
Tranolopril
Mavik
230
Cephalexin
Keflex
231
Lisinopril/HCTZ
Zestoretic
232
Metronidazole
Flagyl MOA: inhibits nucleic acid synthesis by disrupting DNA causing strand breakage Indications: anaerobic bacterial infection/STIs
233
Mometasone/Formoterol
Dulera MOA: glucocorticoid inhaled- mometasone Formoterol LABA
234
Rosuvastatin
Creator most potent
235
Irbesartan
Avapro
236
Acyclovir
Zovirax
237
Metoprolol Tartrate IR
Lopressor
238
Dimethyl fumarate
``` Tecfidera Ms MOA: antioxidant S/E pML flushing Monitor CBC include lymphocytes count ```
239
Gemfibrozil
Lopid.
240
Cangrelor
Kengreal | IV
241
Dabigatran
Direct thrombin inhibitor PO Pradaxa
242
PH
7.35-7.45
243
Beclomethasone
QVAR
244
Baclofen
Lioresal
245
Beclomethasone
QVAR redihaler
246
Fluconazole
Diflucan
247
Isordil titradose | Isosorbide dinitrate
7am noon 5 pm | Nitrate free period >=14 hrs
248
Hydralazine
N/a
249
Cyclosporine
Restasis
250
Fosinopril
Monopril.
251
Pulmicort
Budesonide
252
Glyburide
Glynase, Disney’s | Increases insulin secreation beta cells
253
Ketoconazole topical
Nizoral, Nizoral A-D (otc)
254
Amlodipine
Norvasc
255
QVAR
Beclomethasone
256
Rivaroxaban
Xarelto XA inhibitor 10, 15, 20 mg QD
257
Metoprolol tartrate
Lopressor | Beta blocker
258
Dexlansoprazole
Dexilant
259
Effient.
Prasugrel Anti platlet P2y12
260
Atenolol/Chlorthalidone
Tenoretic
261
Nifedipine ER
Adaptation CC, Procardia XL
262
Omega 3 carboxylic acid
Eponova
263
Septic shock
Levi/ dopamine
264
Ethinyl estradiol and norgestimate
Ortho tricyclen, sprinter, trinessa
265
Catapres-TTS
Clonidine patch | Change every 7 days
266
Nitroglycerin transdermal patch
Mini Tran, Nitro-Dur
267
Acebutolol
Sectral Drug induced lupus Beta blocker
268
Clevidipine
Cleviprex iv
269
Memantine
Namenda. NMDA receptor antagonist Altzheimer type dementia
270
Famotidine
Pepcid
271
Nitroglycerin sublingual spray
Nitrolingual, NitroMist 0.4 mg spray Do not shake container Must prime pump Nitrolinual spray 5 times NitroMist 10 times Bottle is primed for 5 weeks
272
Spiriva respimat
Soft mist inhaler
273
Apixaban
eliquis | XA inhibitor
274
Aggreenox
Aspirin & ER dypyridamole | Decrease risk of stroke in patients with history of TIA and stroke
275
Effexor
Venlafaxine | SNRI
276
Nimodipine
Nimotop
277
ARR | Absolute risk reduction
(% risk control group - % risk trt grp)
278
ICS/LABA
Budesonide/formoterol (symbicort) Fluticasone/ Salmeterol (Advair HFA, Airduo respiclick) Mometasone/formoterol (Dulera) Fluticasone/vilanterol (Breo Elliott)
279
Chlorthalidone
Hygroton, thaline | Diuretics thiazides
280
Dextromethorphan/promethazine
Promethazine DM | Antitussive/1st gen anti-histamine
281
Doxycycline
Vibramycin
282
Meta analysis
Combines results from multiple studies
283
Nitroprusside
Nipride
284
Peridopril
Aceon
285
Apixaban
Eliquis. | 2.5, 5 mg BID
286
Savella
Milnacipram fibromyalgia | SNRI
287
Case report and case series
Case report = single patient Case series = few patients
288
Gemfibrozil
``` Lopid. Fibrin acid derivative Stimulate enzyme lipoprotein lipase increases the li polis is vldl & dec tG Before meals 30 min Inc risk myopathy with statins May increase warfarin, monitor inr ```
289
Cardizem
Diltiazem
290
Nitroglycerin sublingual tabs
Nitrostat Take SL tabs every 5 minutes for chest pain If chest pain persists after one dose dial 911 Max 3 SL tabs in 15 minutes
291
Liodexamfetamine
Vyvanse | Promotes release dopamine & norepi from presynaptic nerve terminals
292
Absolute Neutophil Count
WBC * (%bands + % swag) _____________________ 100 < 1000 neutropenia
293
Aldendronate
Fosamax
294
Clindamycin, topical
Cleocin, clindagel
295
Pegylated interferon beta 1a
Plegridy Subq. Biweekly 14 days Relapsing Ms
296
Captopril
Capoten TID empty stomach
297
Ethinyl estradiol/ etonogestrel
nova ring.
298
Lisinopril
Prinivil, Zestril
299
Prasugrel
Effluent 60 mg loading dose then 10 mg QD Use within 30 days stay in original container Stop 7 days prior to surgery
300
Morphine
MSContin, Kadian, Duramorph
301
Canagliflozin
Invokana | Sglt2 transport inhibitor
302
Pravastatin
Pravachol
303
Cyclobenzaprine
Amrix, Fexmid
304
Isordil tabs, Dilatrate Sr caps
Isorbide dinitrate | No nitrates if systolic bp < 90 mmHG
305
Tirofiban
Aggrastat. | Blocks gp23a
306
Buprenorphine
Belbuca (buccal film) | Butrans (patch)
307
Systematic review article
Specific topic or answers a question Ex- the evolving landscape of advanced renal cell carcinoma in patient progression after VEGF inhibition.
308
Erythromycin
E.E.S. 400, Ery-Tab
309
Milrinone
No brand | For decompensated heart failure
310
Lovastatin
Altoprev
311
Guanfacine.
Alpha-2 agonist Decrease sympathetic outflow ADHD Mech unknown
312
Furosemide
Lasix
313
Heparin induced thrombocytopenia
Argatroban. Bivalridin (Angiomax) FONDAPARINOX (Arixtra)
314
Niacin
Increases risk of myopathy with statins Dec TC, LDL, VLDL Inc HDL Take 325 mg of ASA 30-60 min prior
315
Esmolol
Brevibloc | Beta blocker
316
Isotonicity
E=(58.5)(I) / (MW)(1.8)
317
Lansoprazole
Prevacid, Prevacid 24 hr, Prevacid | Solitaire
318
Cefuroxime
Cefdinir
319
Mometasone,topical
Elocon MOA: corticosteroid topical Indications: dermatitis, pruitus.
320
Matzim LA
Diltiazem
321
Tamsulosin
Flomax | Bph only
322
Levofloxacin
Synthroid, levoxyl, unithroid
323
Cartia XT
Diltiazem
324
Tenoretic
Atenolol/HCTZ
325
Umeclidinium
Incruse Elliott QD
326
Diclofenac topical
Voltaren gel
327
Meloxicam
Mobic. MOA: inhibit Cox 1 and 2 NSAID
328
Nitroglycerin ointment 2%
NitrBID Bid 1/2 inch on rising and 1/2 inch 6 hours later 10 - 12 hr nitrate free period
329
Cipro/Dex
Ciprodex
330
Bupropion
Wellbutrin SR Wellbutrin XL Zyban
331
Hypovolemic shock
Dopamine / Levophed (norepinephrine)
332
Montelukast
Singulair MOA: leukotriene receptor antagonist
333
Lithium
Lithobid Inhibits reuptake postynaptic D2 sensitivity Influences reuptake of seratonin & norepinephrine
334
Ketoralac
Acular
335
Lovastatin
Mevacor, Altocor
336
Total Cholesterol
HDL + LDL + (TG/5)
337
Icosqpent ethinyl
Vacepa Fish oil EPA/DHA
338
Tiotropium
Spiriva handihaler | Dry powder inhaler QD
339
Cohort studies
Compares outcomes of a group of patients exposed and not exposed. To a treatment.
340
Fluticasone
Flovent HFA , Flovent diskcus, Amiity Ellipta.
341
Doxazosin
Cardura.
342
Colesevelam
Welchol Bile acid sequestant Dec ldl
343
Azor
Amlodipine & olmesartan
344
Glimepiride
Amaryl | Increases secreation insulin beta cells
345
Esomeprazole
Nexium, Nexium 24 hr, Nexium IV | PPI
346
Aerospace
Brand d/c flunisolone
347
Zyprexa
Olanzapine | 2nd gen antipsychotic
348
Olmesartan | Olmesartan/HCTZ
Benicar. Arb —- Olmesartan/HCTZ benicar hct
349
Carvedilol
Coreg
350
Omega3/ ethyl ester
Lovaza. | MOa not understood
351
Formoterol & budesonide
Symbicort
352
Glipizide
Glucotrol Increases secretion beta cells Decreases production hepatic glucose
353
Tjrombolytics
Break down fibrin
354
Hydrochloroquine
Plaquenil
355
Methocarbamol
Robaxin Skeletal muscle relaxant MOA: unknown possible CNS depression
356
Tarka
Verapamil & trandolapril ( w/food)
357
Dabigatran
Pradaxa IIa inhibitor 75, 150 mg bid
358
mOsmol/L
Wt/MW * #particles * 1000 | G/L/ G/mole
359
Diphenhydramine
Benadryl
360
Tnkase.
Plasminogen activator | Inhibits fibrinolysis
361
Chlorhexidine topical antiseptic
Hibiclens
362
Colesevelan
Welchol | Bile acid sequestant excreted in feces
363
Neomycin/ polymyxin/hydrocortisone topical
Cortisporin.
364
Fenofibrate
``` Antora, Tricor, Trilipix Increases VLDL metabolism Fibrin acid agents PPAR alpha activator Inc app lipoprotein C2 ```
365
Devenslafaxine
Pristq. | SNRI
366
RRR | Relative risk reduction
1 - RR
367
Linagliptin
Tradjenta
368
Finasteride
Proscar | 5 alpha reductase inhibitor
369
Amitriptyline
Elavil, endep
370
Linaglip
Trajenta | DM2
371
Glatiramer
Relapsing MS Copaxone, Glatopa SQ daily Pregnancy cat B
372
Fluocinonide, topical
Vanos. Corticosteroid Psoriasis
373
Olanzapine
Zyprexa | 2nd gen antipsychotic
374
Glycopyrolate
See bro caps neohaler Bid
375
mmol
mg/MW
376
Case control
Compares patients without disease (control) to patients with disease (retrospective)
377
Clobetasol, topical
Cloned, temovate, Olux
378
Quinipril
Accupril
379
Allopurinol
Zyloprim, Aloprim
380
Vytorin
Simvastatin & ezetimibe
381
Isoptin SR
Verapamil
382
Minocycline
Mini in, Class: tetracycline MOA: inhibits protein synthesis & bacterial growth by binding to 30s and 50s subunits of bacteria Indications community acquired MRSA Gonococcal infection males Chlamydia
383
Metformin
``` Glucophage Glucophage XR Fortamet Glumetza MOA: dec hepatic glucose production Decrease GI glucose absorption Inc. insulin cell sensitivity ```
384
Valsartan
Diovan | ARB
385
CI does not include 0
Statistically significant
386
Bisoprolol/HCTZ
TIAC
387
Enalapril
Vasotec | AceI
388
Metolazone
Zaroxlyn | Thiazides Like diuretic
389
Nabymetone
NSAID Relafen. Inhibits cox1 and cox2
390
Moexipril
Univasc empty stomach
391
Isosorbide mononitrate
Monoket, ISMO Bid 8 am & 3 pm Extended release (imdur.) QD Do not use for acute angina
392
Cetirizine
Zyrtec
393
Nebivilol
Bystolic | Beta blocker
394
Calan SR
Verapamil
395
Carisoprodol
Soma
396
Pitastatin
Livalo | Zypitamag ( with magnesium)
397
Budesonide
Pulmicort | Pulmicort flexhaler
398
Verapamil
Calan, calan Sr, Verelan, Verelan PM
399
Calan
Verapamil
400
Mol
g/MW
401
Cholecalciferol
Vit D3
402
Gabapentin
Neurontin
403
Rivaroxaban
Xarelto No if crcl < 30 ml/min xA inhibitor
404
Ergo calciferol
Vit D2
405
Lovastatin
altoprev
406
Divaloroex/Valproate
Depakene Depakote Anti-convulsants
407
Natalizumab
Tysarbri IV pML mS
408
Interferon beta 1a
Avonex. Rebif. Relapsing MS Avonex IM once weekly Frig Rebif sq 3 times weekly Frig.
409
Ticagrelor
``` Brillianta. Reversible bonds p2y12 Stop 5 days prior to surgery Aspirin dose above 100 mg Reduces effectiveness of Brillinta Loading dose 180 mg Maint. Dose 90 mg bid ```
410
Tekamlo
Amlodipine & aliskiren
411
Heparin
IV Loading dose 80 U/ KG Maint. Dose 18 U/kg/hr Heparin check APTT every 6 hrs
412
MEQ
(Mg x valence) / MW
413
Metaclopramide
Regan | MOA: blocks dopamine receptors at high dose and seratonin receptors
414
Glycopyrolate
Lingala magnair | Nebulizer
415
Cross over rct
Grp 1 receive trt A 1st then crossover to trt B Grp 2 receive trt B 1st then crossover to try A
416
Cholestyramine
Prevalite. Questran. Bile acid sequestrant Dec ldl
417
Atorvastatin
Lipitor | Caudet = amlodipine & Atorvastatin
418
Digoxin
+ionotrope - chronotrope Lanoxin. Lanoxicaps. Digitex.
419
Oxycodone ER
OxyContin
420
Oxycodone /Acetaminophen
Percocet, Endocet
421
Pantoprazole
Protonix
422
Paroxetine
Paxil
423
Amlodipine & Atorvastatin
Caduet.
424
Ezetimibe & Simvastatin
Vytorin
425
Fenofibrate | Fenofibric. Acid
Antara Tricor trillipix Fibrates. Ppar alpha activators
426
Gemfibrozil
Lopid | Fibrates PPAR alpha activators
427
Colesevelam
Welchol Bile acid sequestant Binds to bile acids in intestine and excreted in feces
428
Niacin
Dec tG and ldl
429
Omega 3 and ethyl esters
Lovaza Icosapent ethyl = vasepa. Fish oils MOA: unknown
430
PCSK9 inhibitor
Praluent=alirocumab Evocumab = Repatha. Bind to ldl receptors lowering ldl
431
Trituration
Mix homogeneous
432
Levigation
Tutu ration mortar & pestle inc. liquids
433
Spatulation
Similar to levigation but uses a spatula with pint slab
434
Pulverization
Crystallization powder do not crush easily
435
Ivacaftor
Kalydeco >= 12 yo G551D mutation Granular <6 yo and tabs
436
Tezacaftor-ivacaftor
Symdecko >= 12 yo f608del mutation
437
Luna after-ivacaftor
Orkambi >=2 yo F508del Granules & tabs
438
Alprostadil.
Muse Prostaglandins E1 vasodilator Pellet inserted into urethra for E Caverject - inject corpus cavernossom
439
Lispro.
Humalog, Admelog Room temp 28 days Humalog U-100 (100 U/ mL) humalog U-200 (200 U/ mL)
440
Glulisine
Apidra. Room temp 28 days Rapid acting
441
Refrigerator temp.
(2-8 C) or (36-46 F)
442
Insulin
29-32 gauge | 4 mm needle
443
Interval data
No meaningful zero. | Zero doesn’t = none
444
Ratio data
Zero meaningful | Zero equals none
445
RR relative risk
TG/CG RR as likely
446
RRR relative risk reduction
1-RR | Less likely
447
ARR (absolute risk reduction)
(% risk CG) - (% risk TG) 12 out of 100 patients will benefit from treatment
448
Sildenafil
Viagra, Revatio (pAH) PDE/5 inhibitor Inc camp and inflow of blood inc smooth muscle relaxation
449
Tadalafil
Cialis , Adcirca | PDE/5 inhibitor
450
Vardenafil
Levitra, Staxyn-ODT
451
Ava after
StendrA
452
Oxycodone ER
OxyContin Narcotic agonist - analgesic opiate receptor Inhibits ascending pain pathways
453
Oxycodone/ acetaminophen
Percocet, Endocet
454
Cimetidine
``` Tagamet h2RA Gynecomastia Drowsiness Agitation Diahrrea ```
455
Ranitidine
Zantac IV/IM H2RA
456
Famotidine
Pepcid IV/oral h2RA
457
Nizatidine
Acid | h2RA
458
Prevpac
H.pylori Amoxicillin Clarithromycin Lansiorazole
459
Pylera
H.pylori | Bismuth, metronidazole, tetracycline
460
Vimovo
Esmoprazole & naproxen
461
Metoclopreamide
Replan | Accelerates gastric emptying
462
Yosprala
Omeprazole & Asa
463
Prevpac
CAL Clarithromycin Amoxicillin Landoprazole
464
Pylera
Bismuth Metronidazole Tetracycline
465
Chi squared test
Nominal or ordinal data Nominal data - gender & race Ordinal data - hypoglycemic event severity on a 3 point scale
466
Student t-test
Mean Change in A1C example of continuous data | There are 2 groups making a student t test appropriate
467
ANoVA
Good for 3 groups
468
Mann Whitney test
Data is NOT normally distributed (2 groups) | Wilcox signed rank 1 group with before and after measures
469
Desvenlafaxine
SNRI Pristiq Depression Inc bp
470
Venlafaxine
Effexor MDR, gad, panic disorder xr only Ghost tablet in stool
471
Desvenlafaxine
Khedezla SNRI For MDR Max 400 mg/d with or without food
472
Duloxetine
Cymbalta SNRI Indications: Depression, gad, diabetic peripheral neuropathy, fibromyalgia, chronic muscle skeletal pain including osteoarthritis and chronic lower back pain.
473
Milnacipram
SNRI Fibromyalgia 3 drugs for fibromyalgia Lyrics (pregabalin), Cymbalta (duloxetine). & milnacipram (Savella)
474
Levomilnacipram
Fetzima MDD ESRD: don’t use Avoid alcohol
475
Fluoxetine
SSRI | Prozac
476
Sarafem.
Fluoxetine sSRI pMDD premenstral dysphoric disorder
477
Paroxetine
Paxil’s | SSRI
478
Sertraline
Zoloft | SSRI
479
Citalopram
Celexa | SSRI
480
Escitalopram
Lexapro SSRI S-enantomer of Citalopram
481
Phenerzine
Nardil | MAOI
482
Isocarboxazid
Marplan | MAOI
483
Tranylcypromine
Parnate. | MAOI
484
Selegiline
Emsam Patch MAOI
485
Ariprazole
Ability- antioosychotic | Approved for mdd
486
Olanzapine/fluoxetine
Symbyax Approved for mdd Antipsychotic
487
Quetiapine xr
Seroquel xr
488
Brezpiprazole
Rexulti Mdd Antipsychotic
489
Phentolamine
Regitine. 1-phenochromacytoma 2-cocaine Od. HTN crisis 3- MAOI tyramine HTN crisis
490
Pregnancy HTN
Merhyldopa, Nifedipine, labetalol
491
Felodapam
Corlopam | Renal HTN emergency
492
Ocrelizumab
Ocrevus | Primary progressive MS
493
Cartia.
Diltiazem
494
Cardizem
Diltiazem
495
Dilt-XR
Diltiazem
496
Cartia-XR
Diltiazem
497
Tiazac
Diltiazem
498
Taztia
Diltiazem
499
Matzim. LA
Diltiazem
500
Calan calan Sr
Verapamil
501
Isoptin sr
Verapamil
502
Verelan
Verapamil
503
Candesartan
Atacand
504
Eprosartan
Tevetan
505
Irbesartan
Avapro
506
Losartan
Cozaar
507
Olmesartan
Benicar
508
Telmisartan
Micartis
509
Valsartan
Diovan
510
Azilsartan
Dearborn
511
Tenet
Guafacine | HTN
512
Intuiv.
Guanfacine | ADHD
513
Caduet
Amlodipine & Atorvastatin
514
Adapt
Nifedipine
515
Milrinone
Primacor Chf + ionotrope vasodilator
516
Nesiritide
Natrecor. | Diuretic & vasodilator
517
Entresto.
Sacubitril & valsartan 36 hour wash out period when switching from ACEI Systolic bp >100 mmHG
518
Ziac.
Bisoprolol & hctz
519
Benicar
Olmesartan
520
Treat torsades. De pointe
Magnesium IV
521
Fragmin.
Dalteparin | 2500-5000 U SQ
522
Lovenox
Enoxaparin SQ Lmwh Don’t give with pork allergy
523
Idaruzumab
Praxbind Pradaxa antidote IV
524
Pradaxa.
Dabigatran | Once bottle is opened good for 6 mos
525
Anti-coagulant
Blood thinners inhibit clotting factors
526
Anti-platlets
Inhibit enzymes that cause platlets yo clump together
527
Ranolazine
Renexa For angina Doesn’t lower BP or HR
528
Danazol
No generic Androgen For endometriosis
529
Liptruzet
Atorvastatin & ezetimibe
530
Salmeterol & Fluticasone
Advair | LABA & steroid
531
Formoterol & budesonide
Symbicort | LABA & steroid
532
Formoterol & mometasone
Dulera | LABA & steriod
533
Salmeterol & fluticasone
Airduo respiclick | LABA & steriod
534
Salmeterol
Serevent diskus
535
Salmeterol & fluticasone
Advair
536
Dulera
Formoterol & momentasone
537
Symbicort
Formoterol & budesonide
538
Airduo respiclick
Salmeterol & fluticasone
539
Ipratropium
Atrovent HFA
540
Ipratropium & Albuterol
Combivent respimat
541
Ipratropium & Albuterol nebulizer
Duoneb
542
Tiotropium
Spiriva handihaler dry powder QD
543
Tiotropium respimat
Soft mist inhaler Spiriva respimat pTOP Prime-Turn—Open-Press
544
Umeclidinium
Incruse Elliott QD
545
Aclidinium
Tudorza pressair dry powder
546
Glycopyrolate
Seebri caps in neohaler
547
Glycopyrolate
Lingala magnair nebulizer
548
Revefenacin
Yuperli | QD nebulizer
549
Spiriva
Tiotropium Anticholinergic Dry mouth
550
Nucala
Mepolizumab Blocks IL5 For asthma
551
Norco
Hydrocodone & acetaminophen
552
Lorcet
Hydrocodone & acetaminophen
553
Lortab
Hydrocodone & acetaminophen
554
Vicodin
Hydrocodone & acetaminophen
555
Yosprala
Aspirin and omeprazole
556
Cerebyx
Fosphenytoin
557
Zanaflex
Tizanidine | Alpha 2 agonists
558
Vimovo
Naproxen & esomeprazole
559
Buspar
Buspirone Anti-anxiety High affinity for seratonin 5ht1 & 2
560
Clobetasol
Clobetasol Temovate Olux. Topical corticosteroids
561
Ergo calciferol
Vit D2 | Calciferol
562
Estradiol patch
Vivelle dot Alora Climera
563
Bosentan
Tracleer Oral PAH
564
Ambrisartan
Letaris. Oral Birth defects pAH
565
Eprostenol
Flolan. IV PAH
566
Treprostinil
Tyvaso IV, sc, PO, inhalation PAH
567
Iloprost
Ventavis. Inhalation PAH Dilated pulmonary arteries and prevent blood clots
568
Sildenafil
Ravatio | PAH
569
Tadalafil
Adcirca | PAH
570
Hydroxyzine
Vistaril | Anti histamine
571
Fexofenadine
Allegra | 2nd gen antihistamine
572
Loratadine
Claritin, Alavert | 2nd gen antihistamine
573
Desloratadine
Clarinex | 2nd gen antihistamine
574
Cetirizine
Zyrtec | 2nd gen antihistamine
575
Levocetirizine
Xyzal | 2nd gen antihistamine
576
Ofirmev.
Acetaminophen IV
577
Caldolor
Ibuprofen IV