Topic 2, topic 7, topic 8 Flashcards
(59 cards)
principal sources of energy for brain
Glucose and oxygen which pass rapidly from the blood to the brain cells used to make ATP, supply is limited so there must be continuous supply
Outline blood supply to the brain
left and right carotid arteries and left and right vertebral arteries
Carotid arteries
External: supply blood to the face and scalp
Internal: supply blood to most of the cerebrum
Brachiocephalic trunk: artery that supplies blood to the right arm, head and neck
Blood-Brain-Barrier
protects the brain from foreign substances that may injure the brain, maintains a constant environment for the brain
it is a highly selective barrier that separates the circulating blood from the brain extracellular fluid in the CNS
small molecules like antidepressants and alcohol can slip through endothelial cells, large molecules such as glucose and insulin are transported through proteins
principal source of energy for brain cells
The brain obtains energy using glucose and oxygen, which pass rapidly from the blood to the brain cells
Glucose and oxygen are used to make ATP inside the brain by the process of aerobic respiration
Carbohydrate storage in the brain is limited, so the supply of glucose must be continuous
If blood entering the brain has low glucose or oxygen levels, mental confusion, dizziness, convulsions and loss of conciousness may occur
Brain stem function
respiratory and cardiovascular control centres
Includes:
Diencephalon - Thalamus (perception of sensations cognition)
Hypothalamus (control ANS, Hr, blood pressure, pituitary gland)
cerebrum function
high-level brain functions such as thinking, language and emotion, and motivation. 3 broad processes
1-sensory (receiving sensory impulses)
2- association (interpreting and storing input, and initiating a response)
3- motor (transmitting impulses)
Frontal lobe
Motivation, reasoning and planning
Parietal lobe
Somatic sensory orientation
Occipital lobe
visual sensory and association centre
Temporal lobe
long-term memory
Limbic lobe
emotions and feelings
Cerebellum
maintain balance and posture
smooth out skeletal muscle contractions
motor activities
Circulating hormones
travel around the body in the blood (adrenaline and testosterone)
Local hormones
act on neighbouring cells without entering the bloodstream and are usually inactivated quickly. (glucagon and serotonin)
Hormones
secreted by the endocrine glands to regulate and coordinate a range of bodily functions. Most hormones are released in short bursts, although some are secreted over longer periods of time to stimulate permanent changes in the body.
Hormones affect only specific target cells by (chemically) biding to specific receptors
How circulating hormone levels are regulated
complex feedback loops that may be influenced by
-signals from the nervous system, such as adrenaline
-Chemical changes in the blood, such as insulin
-Other hormones like growth hormones
functions of the conducting airways
low resistance pathway for airflow
defence against chemicals and other harmful substances that are inhaled
Warming and moistening the air
Pulmonary ventilation
Inflow and outflow of air between the atmosphere and the lungs (breathing)
Total lung capacity
Volume of air in the lungs after a maximum inhalation (VC + RV)
Vital capacity
Maximum volume of air that can be exhaled after a maximum inhalation (TV+ERV+IRV)
Tidal volume
Volume of air breathed in and out in any one breath
Expiratory reserve volume
Volume of air in excess of tidal volume that can be exhaled forcibly
Inspiratory reserve volume
Additional inspired air over and above tidal volume
Residual volume
Volume of air still contained in the lungs after a maximal exhalation