TORCH infections

Question 1

Which two viruses can result in hydrops fetalis?

Answer 1

CMV; parvovirus B19

Question 2

Parvovirus B19 infection during the 1st and 2nd trimester(s) can result in:

Answer 2

hydrops fetalis

Question 3

What is the treatment of fetal anemia in a pregnant mother with Parvovirus infection?

Answer 3

Intrauterine RBC transfusion

Question 4

What is the management of a pregnant patient with a positive antibody testing of parvovirus B19 > 20 weeks of gestation?

Answer 4

Weekly ultrasounds

Question 5

What is the management of a pregnant patient with a positive antibody testing of parvovirus B19 < 20 weeks of gestation?

Answer 5

before 20 weeks’ gestation

Question 6

What is the treatment of neonatal HSV infection?

Answer 6

IV acyclovir

Question 7

What is the likely diagnosis in a young patient that presents with two days of fever, altered mental status, seizures, and the lumbar puncture findings below?
- Opening pressure: normal
- Protein: ↑
- Lymphocytes and RBCs: ↑
- Glucose: normal

Answer 7

Herpes encephalitis

Question 8

Rapid Diagnosis Newborn with macrocephaly, hydrocephalus, diffuse intracranial calcifications, chorioretinitis:

Answer 8

Toxoplasmosis

Question 9

In a mother with a toxoplasmosis infection, what is given to the newborn at birth?

Answer 9

Pyrimethamine-sulfadiazine + leucovorin

Question 10

Rapid diagnosis: newborn with maculopapular rash on the soles and buttocks with desquamation, failure to thrive, white nasal discharge, hepatomegaly

Answer 10

Congenital syphilis

Question 11

Which congenital infection is associated with rhinorrhea and desquamating skin rash?

Answer 11

Syphilis

Question 12

• Prolonged rupture of membrane and chorioamnionitis is managed with:
• Prolonged rupture of membrane and postpartum endometritis is managed with:

Answer 12

• Ampicillin + gentamicin
• Clindamycin + gentamicin

Question 13

What is the likely diagnosis in a neonate that presents with hypothermia, hypotonia, poor feeding, and lethargy?

Answer 13

Neonatal sepsis

Question 14

Rapid Diagnosis Newborn with microcephaly, periventricular calcifications, deafness, thrombocytopenia, and petechiae:

Answer 14

CMV

Question 15

What is the most commonly acquired congenital infection?

Answer 15

Cytomegalovirus (CMV)

Question 16

Severe, permanent symptoms of congenital CMV infection are remembered via the mnemonic MR DICS

Answer 16

-Microcephaly
- Restricted intellectual ability intellectual disability
-Deafness
- Intracranial Calcifications (periventricular)
-Chorioretinitis
- Seizures

Question 17

What is the recommended post-exposure prophylaxis for a non-immunized pregnant patient exposed to varicella zoster?

Answer 17

Administer VZIG within 10 days of exposure

Question 18

Pregnant patients with a history of genital HSV infection should receive:

Answer 18

Prophylactic acyclovir or valacyclovir beginning at 36 weeks of pregnancy

Question 19

• No active herpes lesions at delivery =
• Active herpes lesions at delivery =

Answer 19

-vaginal delivery
-C-section delivery

Question 20

Congenital rubella infection is characterized by a classic triad of:

Answer 20

• Cataracts
• Patent ductus arteriosus
• Sensorineural deafness

Question 21

Congenital rubella occurs with infection during which trimester?

Answer 21

First trimester

Question 22

An itchy maculopapular rash that started on the face and spread to the rest of the body but spares the palms and soles, in combination with postauricular lymphadenopathy and polyarthritis, is highly suggestive of :

Answer 22

Rubella