Tox Deadely 12 Flashcards
1
Q
Arsenic
A
- CCA treted wood
- arsenic
- all spp.
- ⛔️kreb cycle ➡️ vasc perm
- GI signs
- 🎖uncoup ox phos➡️sudden death
-RSS succimer💊
2
Q
Blister 🐞🎖
A
- alfalfa hay
- canthardin
- 🐄🐎
- vesicant➡️ulceration: colic
⬇️Ca/Mg, colic, THUMPS - hemorrhagic cystitis
- RSS
3
Q
Cu
A
- non-ovine feeds
- Cu
- 🐑
- accum Cu in liver➡️ hepatocell necrosis
- oxid damage, hemolysis, anemia, Hgb-uric nephrosis ☠️
-RSS
4
Q
EG
A
- antifreeze
- glycolate, oxalate
- all spp
- cytotoxic metabolics➡️❤️ and neuro signs
- 🎖ataxia, PU/PD, Ca oxalate nephrosis
- RSS, ethanol, 4methylprazole
5
Q
Ionophores 🎖
A
- cocciostat 🐓 feed
- monesin
- 🐎🐄 🐖🐕 🚫🐱
- ⛔️ATP Hydrolysis: ⬆️intra Ca
- 💔 necrosis➡️☠️
-RSS
6
Q
Methylxanthines 🍫
A
- 🍫☕️🍵
- theobromine, caffine, theophylline
- 🐶
- ⛔️cyclic nucleotide PDE
⛔️ GABA/adenosine-R
Chatechol rel: Hyperexcitability ➡️☠️ - bouncing dog synd/ 🎖❤️arrhythmias
- RSS Ucath, actv charcoal
7
Q
Lead
A
- batteries, paint
- lead
- all spp, esp growing
- ⛔️enzymes
- mimics [Ca]
heme synthesis - 🐄 blindness/PEM/GI signs
🐶 ⬇️hematopoesis
🐎 PNS. - RSS chelate/thoamine
8
Q
NPN/urea 🎖
A
- Ru feed additive
- NH3
- Ru
-🚫NaK ATPase/kreb
- Rumen ALK ➡️ m.acidosis; bloat, salivation,
🎖hepatoencephalopathy-like effects
- RSS cold water, vinegar 💦
9
Q
Acetaminophen
A
- 💊 tyelenol
- NAPQI
- 🐱
- oxidative damage RBC ➡️ methHgb
- facial/paw edema, hepatocellular necrosis
-RSS, N-acetylcysteine
10
Q
OP
A
- insecticides
- AchE i
- all spp
- inhibiton AchE
- SLUDD
- RSS atropine
11
Q
Rodenticides
A
- anticoag/bromethalin/cholecalciferol
- all spp, 🐶
- ⛔️vit K epoxide rductase: ⬇️vit K CF ➡️blood loss anemia, hypoxia, death
Uncouples ox phosphorylation: CNS sign
⬆️⬆️⬆️ Vit D activit: ST mineralization - RSS, Vit K, plasma transfusion
12
Q
Zinc
A
- post 1982 penny
- Zn
- all spp
- oxid damage RBC ➡️ hemolysis
- hypoxia/🎖Hgb nephrosis
- RSS
