Unlucky 13 Flashcards Preview

Tox Path > Unlucky 13 > Flashcards

Flashcards in Unlucky 13 Deck (13):
1

Endophyte
Tall fescue

Ergot alkaloid

🐄🐎 sm Ru

🐄: VC ➡️ fescue foot, summer slump heat intol
🐎: agalactia

RSS Domperidone

2

Johnson grass 🌾
Pigweed

Sorghum spp

Nitrates & CN

Ru

Nitrate➡️ -ite in rumen

MethHgb-emia➡️ hypoxia ☠️

RSS methylene blue

3

Pigweed & oaks

Nitrates/Unk nephrotoxin/gallotanins

🐄🐷

MethHgbemia

Nephrosis ➡️ proteinuria ➡️ ascites/edema

RSS

4

Oleander

❤️ glycosides

ALLspp. 1° monogastrics

⛔️ NaK ATPase➡️ heart blocks/arrythmias: hypoxia ☠️
GI SIGNS🎖

RSS, decontam GIT

5

Yew

Taxina alkaloids

ALL spp., 1° mono

🚫AP in myocardium ➡️ bradycardia, GI signs, dyspnea ☠️

RSS

6

White 🐍 root

Tremetol

🐎🐄🐑🐐

MOAunk➡️ 🐎 skMm/💔
🐄🐑- CNS depression/liver damage
🐐- liver necrosis

RSS

7

Perilla mint

Perilla ketona

🐄 Bo

Metabolized by respir Clara cells➡️ ☠️type 1 pneumocytes: ✳️ prolif type 2
➡️ ABPEE respir distress, 2° infx

RSS, anti inflam/ABX

8

🍒🍒🍒 tree
Choke cherry

CN

ALL spp: 1° Ru, unless stressed plant

⛔️ cytochrome oxidase/ETC➡️ hypoxia,tachycardia ☠️

RSS, 💊 Na-nitrate, Na-thiosulfate

9

Water hemlock

Cicutoxin

ALL spp

GABA antagonist➡️anxiety, salivation, tremors ☠️

RSS

10

Poison hemlock 🌿🌿🌿

Piperdine alkaloids

All spp: teratogen 🐮

✳️nAchR➡️depol NMB
Anxiety/tremors, salivation

RSS

11

Jimsonweed🌷white

Tropane alkaloids (~atropine)

All
PSNS-lytic effects➡️ mydriasis, tachy, ileus

RSS, AchE inhibitors

12

Yellow ⭐️ thistle

Unk toxin

🐎

⛔️DA-nigrostriatal path ➡️ ataxia, NPallidal encephalomalacia "chewing disease", starve

RSS

13

Senecio/tansy ragwort

Pyrrolizdine alkaloids

🐄🐎

Pyrrole metabolites➡️ ⛔️mitosis: hepatomegaly/CLF

RSS