Toxicants and Metabolites Flashcards

1
Q

Pb ions

A

Pb ions

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2
Q

Tetrodotoxin

A

Tetrodotoxin

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3
Q

TCDD

A

TCDD

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4
Q

HCN

A

HCN

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5
Q

Methylioscyanate

A

Methylisocyanate

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6
Q

CO

A

CO

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7
Q

Amygdalin

A

HCN

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8
Q

Arsenate

A

Arsenite

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9
Q

Fluoroacetate

A

Fluorocitrate

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10
Q

Ethylene glycol

A

Oxalic acid

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11
Q

Hexane

A

2,5-Hexanedione

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12
Q

Acetaminophen

A

N-Acetyl-p-benzoquinoneimine

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13
Q

CCl4

A

CCl3COO*

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14
Q

Benzo[a]pyrene

A

BP-7,8,-diol-9,10-epoxide and BP-radical cation

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15
Q

Hydrogen peroxide

A

Hydroxyl radical (HO*)

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16
Q

Diquat

A

Hydroxyl radical (HO*)

17
Q

doxorubicin

A

Hydroxyl radical (HO*)

18
Q

Cr(V)

A

Hydroxyl radical (HO*)

19
Q

Fe(II)

A

Hydroxyl radical (HO*)

20
Q

Mn(II)

A

Hydroxyl radical (HO*)

21
Q

Ni(II)

A

Hydroxyl radical (HO*)

22
Q

Paraquat

A

O2- + NO -> Peroxynitrite (ONOO-)

23
Q

Sulfonamides

A

albumin-bound bilirubin -> bilirubin

24
Q

CCl3OO*

A

unsaturated fatty acids -> lipid peroxyl radicals, lipid alkoxyl radicals, 4-hydroxynon-2-enal

25
Q

HO*

A

proteins -> protein carbonyls