Toxicities

Question 1

tx methanol toxicity

Answer 1

fomepizole

Question 2

tx ethylene glycol toxicity

Answer 2

fomepizole

Question 3

tx copper toxicity

Answer 3

penicillamine

Question 4

tx mercury toxicity

Answer 4

dimecarpol, succmer

Question 5

tx iron toxicity

Answer 5

defuroxamine

Question 6

tx arsenic toxicity

Answer 6

dimecarpol

Question 7

tx MTX toxicity

Answer 7

leucovorin

Question 8

mode of action of scombroid poisoning

Answer 8

bacterial histidine decarboxylase converts histidine to histamine

Question 9

what toxin is often misdiagnosed as fish allergy

Answer 9

scombroid toxicity (histamine) from dark meaty fish i.e. tuna

Question 10

mode of action of tetrodotoxin

Answer 10

total closure Na channels preventing depolarization

Question 11

mode of action of ciguatoxin

Answer 11

opening of Na channels to cause depolarization

Question 12

toxin which causes nausea, diarrhoea, paraesthesia, weakness and loss of reflexes

Answer 12

tetrodotoxin

Question 13

toxin which causes nausa, vomiting, perioral numbness, hot/cold sensations, bradycardia and hypotension

Answer 13

ciguatoxin

Question 14

indications for haemodialysis in aspirin overdose

Answer 14

metabolic acidosis resistant to treatment
acute renal failure
pulmonary oedema
seizures
coma
salicylate conc > 700

Question 15

abdominal pain, haematemesis and metabolic acidosis

Answer 15

iron toxicity