Toxicity Treatments Flashcards Preview

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Flashcards in Toxicity Treatments Deck (25):
1

Acetaminophen

N-Acetylcysteine
Replenish Glutathione (GSG)

2

AChE Inhibitors
Organophosphates

Atropine: Central and Peripheral
Pralidoxime: Peripheral

3

Antimuscarinic/Anticholinergic Agents

Physostigmine
Control Hyperthermia

4

Arsenic

Dimercaprol
Succimer

5

Benzodiazepenes

Flumazenil

6

Beta-Blockers

Atropine
Glucagon

7

Carbon Monoxide

100% O2
Hyperbaric O2

8

Copper

Penicillamine
Trientine

(Think Wilson's)

9

Cyanide

Nitrite + Thiosulfate
Hydroxycobalamin

10

Digitalis (Digoxin)

Anti-dig Fab fragments

11

Heaparin

Protamine Sulfate

12

Iron

Deferoxamine
Derasirox
Deferiprone

13

Lead

EDTA
Dimercaprol
Succimer
Penicillamine

14

Mercury

Dimercaprol
Succimer

15

Methanol or Ethylene Glycol

1. Fomepizole
2. Ethanol
3. Dialysis

16

Methemoglobin

Methylene blue
Vitamin C

17

Opioids

Naloxone

18

Salicylates

NaHCO3 (Alkalinize urine)
Dialysis

19

TCA's

NaHCO3

20

Warfarin

Vitamin K (Delayed)
FFP (Immediate)

21

Neuroleptic Malignant Syndrome

Dantrolene

22

Serotonin Syndrome

Cyproheptadine

23

Tetrodotoxin MOA

Pufferfish
Binds fast voltage-gated Na+ channels in cardiac/nerve tissue - preventing depolarization

TX: Supportive

24

Ciguatoxin

Reef fish - Barracuda, Snapper, Moray eel
Opens Na+ channels causing depolarization

TX: Supportive

25

Spoiled dark-meat fish - Tuna, Mahi mani, Mackerel, Bonito
(Scombroid poisoning)

Bacterial Histidine decarboxylase converts Histidine to HISTAMINE
Looks like Anaphylaxis

Frequently misdiagnosed as fish allergy
TX: Antihistamines, Albuterol and Epinephrine if needed