toxicology Flashcards

(38 cards)

1
Q

most exposures occur where

A

at home, in the kitchen

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2
Q

most common overall exposure

A

analgesics

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3
Q

most common exposure in kids

A

cosmetics, personal care items

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4
Q

most adult fatalities are associated with-

A

intentional ingestion

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5
Q

most common intervention-

A

decontamination

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6
Q

first step in management

A

ABCDE (including to eliminate the exposure)

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7
Q

Identify the toxin that causes:

coma, miosis, respiratory depression

A

narcotics

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8
Q

Identify the toxin that causes:

dry skin, decreased sweating, mydriasis, fever, confusion, urinary retention

A

anti-cholinergic

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9
Q

Identify the toxin that causes: salivation, lacrimation, diarrhea, emesis, urination

A

cholinergic (like sarin gas)

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10
Q

Identify the toxin that causes: dystonia

A

antipsychotics

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11
Q

suspect MetHb when-

A

central cyanosis that does not improve with 100% O2

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12
Q

treatment for MetHb

A

methylene blue

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13
Q

rapid development of non-cariogenic pulmonary edema with-

A

heroin

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14
Q

cholinergic antidote

A

atropine +2-PAM

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15
Q

antipsychotic antidote

A

benztropine

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16
Q

cyanide antidote (3)

A

sodium thiosulfate
sodium nitrate
hyroxocobalamin

17
Q

digoxin antidote

18
Q

methanol/ethylene glycol antidote (2)

A

ethanol

fomepizole

19
Q

benzo antidote

20
Q

acetaminophen antidote

A

N-acetylcysteine

21
Q

opiate antidote

22
Q

anti-cholinergic antidote

A

physostigmine

23
Q

heparin antidote

A

protamine sulfate

24
Q

warfarin antidote

25
INH seziures antidote
pyridoxine
26
lead chelator
CaNa2EDTA
27
iron chelator
deferoxamine
28
arsenic, gold, mercury chelator
dimercaprol (BAL)
29
copper chelator
d-penicillamine
30
peak hepatotoxicity in acetaminophen OD
72-96 hours
31
lead inhibits:
d-ALA hydratase | ferrochelatase
32
acute lead exposure sign
acute abdominal pain
33
test for chronic/intermittent lead exposure
ZPP
34
cadmium has a
long t1/2
35
most sensitive indicator of serious iron poisoning
vomiting
36
mees lines are seen in-
arsenic poisoning
37
brain finding in CO poisoning
bilateral necrosis of globus pallidus
38
CN binds to
cytochrome c oxidase (complex IV)