Toxidromes Flashcards
Cholinergic response to heart rate
Variable effect. May increase or decrease.
Cholinergic response to pupils
Pupil constriction
Cholinergic response to blood pressure
Variable effect to blood pressure (may increase or decrease)
Name the cholinergic responses to: Pupil Size Heart Rate Blood Pressure Respiratory Rate Bowel Sounds Diaphoresis Temperature
Pupil Constriction Variable effect on HR Variable effect on BP Decreased bowel sounds Decreased Diaphoresis No effect on temperature
A combination of muscarinic and nicotinic effects describe which toxidrome?
Cholinergic
Enumerate the muscarinic effects
(DUMBELS)
Diarrhea, Urination, Mydriasis, Bradycardia, Bronchorhea, Emesis, Lacrimation, Sweating
Name the sympathomimetic effects to pupils size, HR, BP, RR, bowel sounds, temperature, and diaphoresis
Inc. pupil size Inc. HR Inc. BP No effect on bowel sounds Inc. diaphoresis Inc. temperature
Provide the ANTI-CHOLINERGIC EFFECTS to the following: Pupils HR BP RR Bowel Sounds Temperature Diaphoresis
Pupil dilation Increased HR and BP No effect on RR Decreased bowel sounds Decreased diaphoresis Increased temperature
Provide the OPIOID EFFECTS to the following: Pupils HR BP RR Bowel Sounds Temperature Diaphoresis
Pupil constriction Dec. HR Dec. BP Dec. RR Dec. Bowel sound No effect on diaphoresis Dec. Temperature
Provide the SEDATIVE EFFECTS to the following: Pupils HR BP RR Bowel Sounds Temperature Diaphoresis
No effect on pupil size Dec. HR Dec. BP Dec. RR Dec. Bowel sounds Dec. Temperature Dec. Diaphoresis
“Hot as a hare, red as a beet, dry as a bone, blind as a bat, mad as a hatter”
What toxidrome does this mnemonic refer to?
ANTI-CHOLINERGIC TOXIDROME
Name some examples of sympathomimetic drugs.
Epinephrine, norepinephrine
Name some examples of anti-cholinergic drugs.
"Anti-cholinergic meds are 'AT CAMP.'" Anti-histamines TCAs Cyclobenzaparines Anti-spasmodics Mydriatics Parkinson's meds
Give some examples of substances that produce cholinergic effects.
Carbamate insecticides Organophosphates Physostigmine Nicotine Pilocarpine
What effects do BENZODIAZEPINES have on the following: Pupils HR BP RR Bowel Sounds Temperature Diaphoresis
No effect on the pupils Dec. HR Dec. BP Dec. RE Dec. bowel sounds No effect on diaphoresis Dec. Temperature