Toxiocokinetics_L2 TQs Flashcards
1
Q
What determine acute toxicity?
A
rate of absorption
2
Q
What determines the extent of the toxic effects of a substance?
A
the dose
3
Q
What is ED50?
A
Effective dose in 50% of the individuals
4
Q
What is LD50?
A
Lethal dose in 50% of individuals
5
Q
Whis is LC50?
A
Lethal concentration in 50% of the individuals
6
Q
List 7 Extrinsic factors that afffect
Toxicokinetics and -dynamics
A
- Drug-drug interactions
- Environment
- Smoking/diet
- Alcohol use
- Regulatory
- Medical practice
- Others
7
Q
A
