Toxoplasma gondii Flashcards
DH
domestic felids
IH
almost all warm- blooded animals
Ingestion of ___ tissue and digestion of ____ starts the life cycle
IH; sarcocysts
Usporulated oocysts are passed in feces, then sporulation occurs where?
OUTSIDE of the host
Sporulation occurs in __-__ days
1-5 days (about 48 hours)
Oocysts are infective to DH and IH when ____
sporulated
Ingestion of sporulated occyst occurs by the DH or IH?
IH
IH–> extraintestinal excystation to _____
sarcocyst
____ cysts (bradyzoites) can be ingested by humans in uncooked meat or contaminated food/water
tissue
IH–> ______ transmitted through ______
Tachyzoites; placenta and mammary (vertical transmission)
Infectious stage of DH:
Sporulated oocyst
Infectious stage of IH:
Tissue cyst, sporulated oocyst
route of transmission
oocysts are ingested (direct), ingestion of tissue cysts in IH (INdirect), transplacental or transmammary transmission can occur BUT is rare
PPP
3-10 days
Clinical signs of felids
Usually subclinical; Cats with clinical disease are unlikely shedding Oocysts
“Feline toxoplasmosos”- concurrent infection, immunosuppression, fever, weight loss, lethargy, anorexia, Retinochoroiditis, uveitis, encephalitis, myocarditis
Clinical signs of sheep
abortions
Clinical signs of goats
abortions
Clinical signs of cattle
resistant to infection, seropositive, tissue cysts are undetectable
Clinical signs of chickens
resistent to infection, seropositive, DOOOOO have tissue cysts
Clinical signs in Horse:
resistent
clinical signs in Dogs:
toxoplasmosis is rare, vertical transmission is rare
clinical signs in wildlife
seroprevalence high in may wildlife populations, clinical toxoplasmosis in species including marsupials, non-human primates and etc.
Clinical signs in Humans
abortions
Some animals also experience this
behavioral changes (IN IH) after infection
