transcription Flashcards
(8 cards)
1
Q
what does the Assembly of the Pre-Initiation Complex require?
A
General Transcription Factors that Recruit Pol II
Figure 26-16 part 2
7
2
Q
what do Upstream activators bind to?
A
short regulatory DNA
sequences
3
Q
are Transcription factors are trans-acting factors?
A
yes
4
Q
Transcription factors can work in different ways to
either….
A
- Increase assembly of the pre-initiation complex
- Increase RNA polymerase II release from the PIC to
initiate transcription
5
Q
what domains do Transcription Activators have ?
A
DNA Binding Domain and
an Activation Domain
6
Q
what are the different transcription patterns for transcription factors?
A
- Expressed in all cells – activate housekeeping genes
- Expressed in tissue-specific way – active tissue-specific
genes - Expressed in inactive form and activated in response
to environment
7
Q
what are LCRs?
A
locus control regions
8
Q
A