Transfusion Flashcards
(7 cards)
1
Q
What is donor blood tested for?
A
HIV HCV HBV Syphillis HTLV HEV
2
Q
indications for Red cell transfusion?
A
Anaemia
Acuted blood loss
3
Q
Indicaiton for FFP transfusion?
A
Bleeding or surgery in liver disease with imparied coag
Coagulopathy
DIC
4
Q
How does Acute haemolytic transfusion reaction occur?
A
Complement and MAC rupture red cells
Thromboplastic material leads to activation of coag mechanism–> DIC
Bradykinin
5
Q
How long does a delayed haemolytic reaction usually take to set in?
A
5-10 days post transufsion
6
Q
Features of DHTR?
A
Similar to acute reaction
Unexplained fall in Hb
Jaundice, renal failure, biochemical features associated with IHTR
7
Q
Investigation of febrile non haemolytic transfusion reactions
A
HLA antibodies may be detectable
No evidence of red cell incompatibility
