Transfusion Medicine Flashcards
(57 cards)
What is the Canadian Blood Services responsible for?
- donor screening
- collecting blood from volunteer donors
- blood typing
- performing testing to ensure the blood supply is safe
- producing blood components such as packed red cells, plasma and platelets
- matching bone marrow donors and recipients
What is the primary donation given to the CBS?
whole blood
What is a specialized collection called?
Pheresis
What types of pheresis collections are there?
Collecting of:
- plasma
- platelets
- WBC
How is pheresis done?
whole blood is removed from donor, centrifuged and filtered to separate the desire components, then the remainder is returned to the donor
How is the most plasma donated in Canada?
By apheresis
What is AUTOLOGOUS DONATION?
When a patient donates whole blood for themselves to use.
What tests are done before sending it to Transfusion Medicine that is related to the blood cells itself?
- ABO grouping; extended RBC phenotype
- Rh (rhesus) typing
- antibody screening
What tests are done before sending it to Transfusion Medicine that is related to disease testing?
- Hep B surface antigen and hep-B core antibody
- Anti-HCV/HIV/HTLV
- syphilis screening
- West Nile virus
What’s the difference between blood COMPONENTS and blood PRODUCTS?
Components = the actual components of your donation (i.e. packed red cells, plasma and platelets)
Products = made from your blood; produced from your blood
What is packed red blood cells?
When you remove as much plasma and WBC as you can from donated whole blood.
What is the packed red blood cells for?
It’s used for patients with decreased oxygen carrying capacity (symptomatic anemia)
How is packed red blood cells stored?
For 42 days in a fridge
What is Fresh Frozen Plasma?
plasma that has been collected by plasmapheresis OR prepared from whole blood and is frozen within 8 hours of collection
When is plasma considered Frozen Plasma then?
if the plasma is frozen after 8 hours of collection
How is plasma stored?
in a freezer that is less than -18c for one year
What is plasma used for?
patients with deficiencies of coagulation factors
Why are platelets given to some patients?
It’s because some: patients who can’t produce enough of their own platelets; patients whose platelet function is impaired
How do you store platelets?
at room temperature for up to 5 days WITH continual mechanical agitation
Do blood components or blood products have lot numbers?
blood products do
What are some examples of blood products?
- coagulation factor concentrates
- IV immune globulin
- hyper immune globulins
- Rh immune globulins
- albumin
What is coagulation factor concentrates used for?
patients with bleeding disorders
What do patients with hemophilia get?
Factor VIII concentrates
*they self-administrate at home to prevent/control bleeding
How are clotting factor/coagulation factor concentrates made?
they are derived from pooled donor plasma or recombinant DNA technology
