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IMMUNOLOGY > Transplant Immunology > Flashcards

Transplant Immunology Flashcards

1
Q

organ from same individual

A

Autograft

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2
Q

organ from same species

A

Allograft

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3
Q

Organ from identical twins

A

Isograft / Syngeneic graft

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4
Q

Organ from different species

A

Xenograft

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5
Q

Best allograft survival rate

A

Cornea

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6
Q

Cornea transplant is prone to

A

Creutzfeld Jacob Syndrome

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7
Q

It has the best survival rate if it came from a living donor

A

Kidney Transplant

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8
Q

Recipient assumes ____ blood type after BM transplantation.

A

Donor ABO

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9
Q

Onset: Occurs within minutes
Mechanism: Humoral
Cuse: Preformed cytotoxic antibodies

A

hyperacute

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10
Q

Onset: 2-5 days
Mechanism: Cell Mediated
Causes: Sensitization

A

Accelerated

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11
Q

Most common Transplant Rejection
Onset: 7-21 days
Mechanism: Cell Mediated
Causes: Allogeneic reaction

A

Acute

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12
Q

Onset: Later than 3 months
Mechanism: Cell mediated
Causes: DISTURBANCE of host-graft tolerance

A

Chronic

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13
Q

Onset: Later than 3 months

Mechanism:
1. Immune Complex disorder
2. Complement formation with soluble antigens

Causes:
Necessitating transplantation

A

Immunopathologic damage to new organ

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14
Q

Onset: Varies
Mechanism: Cell mediated
Causes: T cells rejects host cells

A

Graft-Versus-Host Disease

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15
Q

Bence Jones Protein Coagulates @

A

40-60 deg Cel

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16
Q

Bence Jones Protein Dissolves @

A

100 deg Cel

17
Q

Malignancy in Plasma Cells
BJP in urine

A

Multiple Myeloma

18
Q

Autoimmune Disease
Oligoclonal bands in CSF

A

Multiple Sclerosis

19
Q

Tumor marker related to Lewis Blood Group

A

CA 19-9

20
Q

Prognostic Marker and Therapeutic choice for Breast Cancer

A

Estrogen Receptor
Progesterone Receptor

HER-2/Neu

21
Q
A

IMMUNOLOGY (8 decks)

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