Trauma - ICU and ward management Flashcards
(112 cards)
What is the primary goal in the management of a shocked patient in ICU?
Establish adequate oxygen delivery
Supranormal resuscitation has been shown to lead to poorer outcomes; now the approach is goal-directed.
What are the indications for intubation?
- Airway obstruction or inability to protect airway (inadequate gag reflex)
- Inability to breathe (e.g., paralysis, high spinal injury, tidal volume <5ml/kg)
- Poor ventilation leading to respiratory failure (Poor PaO2 + PaCO2)
- Systolic pressure <75mmHg despite adequate resuscitation
- GCS <8/15
- Temperature <32°C
What is the target range for PaCO2 during ventilatory support?
35-40mmHg
Avoiding respiratory alkalosis is important due to its effects on the haemoglobin dissociation curve and cerebral vasoconstriction.
What is the target range for PaO2 during ventilatory support?
80-100mmHg with the lowest possible inspired O2 concentration
Which pharmacological agent is preferred for acute trauma in ICU management?
Noradrenaline
It has potent inotropic effects and activates myocardial β-adrenergic and vascular α-adrenergic receptors.
What are the primary effects of adrenaline in ICU management?
- Peripheral vasoconstriction
- Increased systemic vascular resistance
- Increased systolic and diastolic BP
- Increased myocardial electrical activity
- Increased coronary and cerebral blood flow
- Increased myocardial contraction strength
- Increased myocardial oxygen requirement
What is the role of dopamine in ICU management?
- Stimulates dopaminergic and adrenergic receptors in a dose-dependent manner
- Low dose causes vasodilation and increased urinary output
- Higher doses cause increased systemic vascular resistance and preload
What are the effects of dobutamine?
- Potent inotropic effects through β1 and α1-adrenergic receptor stimulation
- Increases cardiac output
- Reduces peripheral resistance
- Less likely to induce tachycardia compared to adrenaline
What is the effect of isoproterenol/isoprenaline?
Strong chronotropic effect
It has largely been superseded by dobutamine in clinical use.
What is the primary function of nitroprusside?
Potent peripheral vasodilator with balanced effects on systemic and pulmonary circulation
What is the limitation of digoxin in shock management?
Significant time to act limits its usefulness; usually used to treat atrial fibrillation or supraventricular tachycardia.
Fill in the blank: The indication for intubation includes a GCS of _____ or less.
8/15
True or False: Supranormal resuscitation is now the recommended approach for managing shocked patients.
False
α1-receptors
- list three α1-receptor agonists and summarise their effect
Noradrenaline>adrenaline»isoprenaline
Smooth muscle contraction, mydriasis, vasoconstriction in skin, mucosa, abdominal organs, sphincter contration in GI tract and bladder
α2-receptors
- list 3 α2-receptor agonists and summarise their effect
Adrenaline=noradrenaline»isoprenaline
act on smooth muscle
β1-receptors
List 3 β1-receptor agonists and summarise their effect
Isoprenaline>noradrenaline>adrenaline
Positive chronotropic, inotropic effects
β2-receptor
-list three β2-receptor agonists and summarise their effects
Isoprenaline>adrenaline>noradrenaline
Smooth muscle relaxation (bronchodilation)
β3-receptor
- list β3-receptor agonists and summarise their effects
Isoprenaline >noradrenaline=adrenaline
Enhanced lipolysis, bladder relaxation
What is a potential complication of trauma related to hypothermia?
Risk factor for cardiac arrest
Hypothermia can lead to various complications, including the risk of cardiac arrest due to impaired physiological responses.
What is the neuroprotective aspect of hypothermia?
Hypothermic patients are neuroprotective
Hypothermia can provide protection to the brain during periods of reduced blood flow or oxygen supply.
When can a hypothermic patient be declared dead?
Cannot be declared dead until near-normal body temperature reached
This is important to prevent misdiagnosis of death in hypothermic patients.
What should be done if a hypothermic patient’s temperature is below 29.5°C?
Rapidly re-warm
Immediate re-warming is critical to prevent further complications and improve patient outcomes.
What is the recommended action for a hypothermic patient with a temperature between 30-32°C?
Use passive re-warming, but often active core warming
Active methods may be necessary to ensure effective re-warming.