Treatment of Clinical Disorders Flashcards
(67 cards)
what are the different goals of treatments of disorders?
direct intervention, symptom support, or insight-based
what are the problems with determining if treatment is working?
- self reports are unreliable
- the worst symptoms often go away on their own
- placebo effects
- nocebo effects
what are nocebo effects?
incorrect expectations about illness progression or treatment outcomes make our symptoms worse
what is treatment efficacy vs effectiveness?
efficacy is how well the treatment works in ideal conditions; effectiveness is how well the treatment works in real-life conditions
what is the function of the active control group in an RCT?
by administering standard or mock treatment, the active control measures efficacy compared to the new intervention and measures placebo/nocebo effects
what is the function of the inactive control group in an RCT?
measures efficacy compared to doing nothing, natural improvement, and patient bias for assessing pre/post symptoms
what is natural improvement?
the tendency of symptoms to return to their mean or average level
what is reconstructive memory?
client’s motivation to get well causes errors in reconstructive memory for the original symptoms (“getting what you want by revising what you had”)
what is the function of serotonin?
feelings of well-being, appetite, and sleep
what is the function of dopamine?
increasing activity in various brain regions, especially those related to reward and pleasurable feelings
what is the function of GABA?
primarily related to inhibiting neuronal activity (more GABA = less activity)
what is the function of norepinephrine?
increasing arousal and sense of alertness, especially when stress response is occurring
what is the function of typical antipsychotics?
exclusively block dopamine receptors, reducing the effects of dopamine in the brain; good for positive symptoms
what is the function of atypical antipsychotics?
block activity of both serotonin and dopamine; fewer side-effects and helps with some negative symptoms
what conditions are treated with antipsychotics?
schizophrenia, bipolar, and treatment-resistant depression
what are the limitations of antipsychotics
significant side-effects, and not always as good for treating negative symptoms
what are anxiolytics used for?
anxiety (general and specific), sleep disorders, PTSD, OCD
what are the limitations of anxiolytics?
only alleviates symptoms and builds a strong drug tolerance
what are antidepressants used for?
anxiety, depression
what are the three main types of antidepressants?
SSRIs, SNRIs, Bupropion
what do SSRI’s do?
increase serotonin available in the brain
what do SNRI’s do?
increase both serotonin and norepinephrine
what does bupropion do?
increases norepinephrine and dopamine (also used to stop smoking)
what are some limitations of anti-depressants?
take time to start working, require increasing dosage or change over time