Treatment of Staphylococcus

Question 1

What drugs Cover MRSA (7)?

Answer 1

Ceftaroline
Dalbavancin
Daptomycin
Linezolid
Ortiavancin
Tedizolid
Vancomycin

Question 2

What are the 1st line IV agents for Methicillin-sensitive Staphylococus?

Answer 2

Oxacillin
Nafcillin
Cefazolin

Question 3

What are the 1st line PO agents for Methicillin-sensitive Staphylococcus?

Answer 3

Dicloxacillin
cephalexin
Cefadroxil

Question 4

What are additional IV agents for Methicillin-Sensitive Staphylococcus?

Answer 4

Cephalosporins
Carbapenems
Beta-lactam/beta lactamase combinations

Question 5

What are additional PO agents for Methicillin-sensitive Staphylococcus?

Answer 5

Augmentin (amoxicillin/clavulanate)
Cephalosporins

Question 6

What are the 1st line IV agents for Methicillin-resistant Staphylococcus?

Answer 6

Vancomycin
Linezolid
Daptomycin
Ceftaroline
Ortivancin
Televancin
Dalbavancin

Question 7

What are the 1st line PO agents for Methicillin-resistant Staphylococcus?

Answer 7

Linezolid
TMP-SMX
Doxycycline
Clindamycin

Question 8

What are the additional PO agents for Methicillin-Resistant Staphylococcus?

Answer 8

Tedizolid
Delafloxacin

Question 9

If a Methicillin-resistant Staphylococcus infection persists after Vancomycin what drug do you switch to?

Answer 9

Daptomycin

Question 10

If a Methicillin-resistant Staphylococcus infection persists after switching to Daptomycin what drug do you use next?

Answer 10

Vancomycin + Ceftaroline or Daptomycin + Ceftaroline

Question 11

What are the common adverse effects of Linezolid?

Answer 11

Thrombocytopenia
Interaction with MAO-I Drugs

Question 12

What are the common adverse effects of Daptomycin?

Answer 12

CPK elevation
Not effective in the lung

Question 13

What drugs are used to treat minor MRSA infections of the skin (5)?

Answer 13

TMP-SMX
Clindamycin
Doxycycline
Linezolid
Delafloxacin