Treatment Of Viral And Fungal Pneumonia

Question 1

Drugs inhibit uncoating and replication of viral RNA

Answer 1

Amantadine
Rimantadine

Question 2

Drugs treat influenza A infections within the first 48 hours and used for prophylaxis during flu season

Answer 2

Amantadine
Rimantadine

Question 3

From their adverse effects are
CNS effects
GI dysfunction

Answer 3

Amantadine
Rimantadine

Question 4

Drugs that inhibit neuraminidase enzyme

Answer 4

Zanamivir
Oseltamivir( tamiflu)

Question 5

Used in treatment and prophylaxis of acute uncomplicated influenza infection
Effective against both A and B

Answer 5

Zanamivir
Oseltamivir

Question 6

From its adverse effects are
Abdominal pain and GI dysfunction

Answer 6

Oseltamivir

Question 7

Drug may cause bronchospasm

Answer 7

Zanamivir

Question 8

Drug inhibit viral RNA polymerase and it is a prodrug

Answer 8

Ribavirin

Question 9

Drug used in treatment of
RSV
HCV
HBV
In combination with interferon alpha

Answer 9

Ribavirin

Question 10

Drug may cause
Hemolytic anemia
Teratogenicity in pregnancy

Answer 10

Ribavirin

Question 11

Drug inhibits the activity of viral DNA polymerase

Answer 11

Acyclovir

Question 12

Used to treat HSV type 1 and 2

Answer 12

Acyclovir

Question 13

Used in treatment of Epstein Barr virus

Answer 13

Acyclovir

Question 14

Treat varcilla zoster virus

Answer 14

Acyclovir

Question 15

Treat cytomegalovirus

Answer 15

Acyclovir

Question 16

May cause well tolerated nausea, diarrhea and headache

Answer 16

Acyclovir

Question 17

May cause nephrotoxicity and neurotoxicity reversible if given I.V

Answer 17

Acyclovir

Question 18

Drug that is similar to acyclovir but highly active against CMV

Answer 18

Gancyclovir

Question 19

Adverse effects of gancyclovir are

Answer 19

Neutropenia ( reversible)
Thrombocytopenia

Question 20

.

Is a drug of choice for systemic blastomycosis

Answer 20

Itraconazole

Question 21

Drug of choice for systemic candidiasis and cryptococcal meningitis

Answer 21

Fluconazole

Question 22

Drug of choice for invasive aspergillosis

Answer 22

Voriconazole

Question 23

Inhibitor of nucleic acid synthesis

Answer 23

Flucytosine

Question 24

Inhibit nucleic acid synthesis

Answer 24

Flucytosine

Question 25

May cause - Depression of bone marrow at high doses - Hair loss

Answer 25

Flucytosine

Question 26

Inhibit beta glucan

Answer 26

Echinocandines ( caspofungin)

Question 27

Used in severe invasive aspergillosis

Answer 27

Caspofungin

Question 28

Used in treatment of esophageal candidiasis

Answer 28

Caspofungin

Question 29

May cause skin rash or itching

Answer 29

Caspofungin