Treatment/Prognosis

Question 1

What is the initial Tx for OP?

Answer 1

Steroids are the mainstay initial Tx for OP. (Smitt MC et al., Semin Radiat Oncol 1999)

Question 2

What are the response rate and long-term control rate with a single steroid course?

Answer 2

Response rate: 80%

Long-term control rate: 33%

(Mombaerts I et al., Ophthalmology 1996)

Question 3

What is the 2nd-line therapy for OP?

Answer 3

RT is the 2nd-line therapy for OP for pts with contraindications, unacceptable toxicity, or inadequate response to steroid therapy.

Question 4

What is the most common RT dose/fx schedule for OP?

Answer 4

20 Gy in 10 fx is the most commonly employed schedule for OP.

Question 5

What are the estimated control rates for OP with RT?

Answer 5

Control rates with RT range from 66%–100%. (Smitt MC et al., Semin Radiat Oncol 1999)

Question 6

What is the standard RT setup for OP?

Answer 6

There is no standard RT setup, as the process may involve any aspect of the orbit. Tx must be individualized.

Question 7

Can RT be repeated for OP?

Answer 7

Yes. RT can be repeated, if necessary.