Background

Question 1

What is an orbital pseudotumor (OP) and how does it most commonly present?

Answer 1

OP is an idiopathic benign lymphocytic inflammatory process causing a mass lesion in the orbit.

OP most commonly presents with sudden unilat proptosis and diplopia.

Question 2

What is the eponym given to OP with cavernous sinus involvement?

Answer 2

Tolosa–Hunt syndrome is OP with cavernous sinus involvement. It manifests with painful ophthalmoplegia d/t CN involvement.

Question 3

What % of pts with OP will subsequently develop a malignant lymphoma?

Answer 3

5%–25% will subsequently develop a malignant lymphoma. (Orcutt JC et al., Br J Ophthalmol 1983; Mittal BB et al., Radiology 1986)

Question 4

Does OP affect children, adults, or both?

Answer 4

OP affects both children and adults. 5%–15% are pediatric cases. (Smitt MC et al., Semin Radiat Oncol 1999)

Question 5

Name 5 signs/Sx associated with OP.

Answer 5

Signs/Sx associated with OP:

Orbital mass
Orbital pain
Proptosis
Abnl extraocular movements (e.g., diplopia)
Decreased visual acuity