Treatments

Question 1

What is the recommended treatment for Stage 0 (Occult NSCLC)?

Answer 1

Surgical resection followed by close follow-up.

Question 2

What is the primary treatment for Stage I NSCLC?

Answer 2

Surgical resection with close monitoring.

Question 3

What is the recommended adjuvant chemotherapy for Stage II NSCLC after surgical resection?

Answer 3

Vinorelbine and cisplatin.

Question 4

What is the common treatment approach for Stage III NSCLC where surgery is not an option?

Answer 4

Chemotherapy and radiotherapy (RT).

Question 5

What treatment is recommended for Stage IV NSCLC in a strong patient without EGFR mutation?

Answer 5

Chemotherapy.

Question 6

What is the first-line treatment for a Stage IV NSCLC patient with EGFR mutation?

Answer 6

TKI (e.g., Erlotinib, Gefitinib, Afatinib) plus chemotherapy.

Question 7

What is the recommended treatment for Ductal Carcinoma in Situ (DCIS)?

Answer 7

Mastectomy or Lumpectomy with radiation therapy (RT).

Question 8

When is Breast-Conserving Surgery (BCS) preferred for early-stage breast cancer?

Answer 8

If the tumor is small.

Question 9

What is the goal of neoadjuvant therapy in Stage III breast cancer?

Answer 9

To reduce disease bulk and make the patient a candidate for surgery or radiotherapy.

Question 10

What is the standard treatment for Stage I colorectal cancer?

Answer 10

Surgical resection of the tumor.

Question 11

When is adjuvant chemotherapy recommended for Stage II colorectal cancer?

Answer 11

If poor prognostic factors are present.

Question 12

What systemic chemotherapy is the backbone for treating metastatic colorectal cancer?

Answer 12

5-FU or capecitabine.

Question 13

What is a standard treatment for early-stage hepatocellular carcinoma?

Answer 13

Surgical resection or liver transplantation.

Question 14

What is the first-line treatment for advanced HCC?

Answer 14

Combination therapy with Atezolizumab and Bevacizumab.

Question 15

What is the standard surgical procedure for tumors in the pancreatic head?

Answer 15

Whipple’s procedure (pylorus-preserving pancreatico-duodenectomy).

Question 16

What is the first-line single-agent therapy for metastatic pancreatic cancer?

Answer 16

Gemcitabine.

Question 17

What is the typical chemotherapy regimen after debulking surgery in ovarian cancer Stage IIIC?

Answer 17

Platinum (Cisplatin or Carboplatin) and Taxane (Docetaxel or Paclitaxel).

Question 18

What surgical option is recommended for very small Stage I cervical cancer if fertility preservation is desired?

Answer 18

Radical trachelectomy.

Question 19

What is the standard treatment for uncomplicated endometrial carcinoma (Stage I)?

Answer 19

Total Abdominal Hysterectomy Bilateral Salpingo-oophorectomy (TAHBSO).

Question 20

What treatment is recommended for very weak Stage IV NSCLC patients?

Answer 20

Supportive care including pain relief and nutrition.

Question 21

What alternative treatment can be given to patients with LCIS who refuse excision?

Answer 21

SERM tamoxifen for 5 years followed by regular monitoring.

Question 22

What adjuvant therapy is recommended for ER-positive early-stage breast cancer in postmenopausal women?

Answer 22

Oral aromatase inhibitors (e.g., anastrozole, letrozole, exemestane).

Question 23

What chemotherapy regimen is commonly used for Stage III colorectal cancer?

Answer 23

Oxaliplatin-based adjuvant chemotherapy.

Question 24

What is the treatment of choice for intermediate-stage HCC?

Answer 24

Transarterial Chemoembolization (TACE).

Question 25

What is the median survival for patients treated with adjuvant FOLFIRINOX after pancreatic cancer surgery?

Answer 25

54 months.

Question 26

What targeted therapy is used for pancreatic cancer with BRCA1/2 or PALB2 mutations?

Answer 26

PARP inhibitors (e.g., Olaparib).

Question 27

What is the median survival for Stage IIIC ovarian cancer with no gross residual disease after resection?

Answer 27

39 months.

Question 28

What additional treatment is often combined with chemotherapy for Stage IV cervical cancer?

Answer 28

Biological agents.

Question 29

What hormonal therapy is used for advanced uterine cancer?

Answer 29

Progestational agents like hydroxyprogesterone, megestrol, or deoxyprogesterone.

Question 30

What is the preferred therapy for rapidly progressive visceral metastases in breast cancer?

Answer 30

Single-agent therapy to minimize toxicity.

Question 31

What are the side effects of bevacizumab used in targeted therapy for colorectal cancer?

Answer 31

Hypertension and impaired wound healing.

Question 32

What surgical option is available for Stage III HCC patients without cirrhosis?

Answer 32

Major hepatectomy, though prognosis is poor.

Question 33

What is the median overall survival for patients treated with nab-paclitaxel and gemcitabine?

Answer 33

6–11 months.

Question 34

Which TKIs are used for adenocarcinoma with EGFR mutations in NSCLC?

Answer 34

Erlotinib, Gefitinib, Afatinib.