Tumor Markers Flashcards Preview

USMLE 1 > Tumor Markers > Flashcards

Flashcards in Tumor Markers Deck (12)
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1
Q

Alkaline phosphatase

A
  • Metastases to bone, liver
  • Paget disease of bone
  • Seminoma
2
Q

alpha-fetoprotein (AFP)

A
  • Hepatocellular carcinoma
  • Hepatoblastoma
  • Yolk sac (endodermal sinus) tumor
  • Testicular caner
  • Mixed germ cell tumor (also B-hCG)
  • Anencephaly
3
Q

B-hCG

A
  • Hyatidiform moles
  • Choriocarcinoma
  • Testicular cancer
4
Q

CA-15-3/ CA-27-29

A

Breast cancer

5
Q

CA-19-9

A

Pancreatic adenocarcinoma

6
Q

CA-125

A

Ovarian cancer

7
Q

Calcitonin

A

Medullary thyroid carcinoma

8
Q

CEA

A
  • Non-specific but produced by 70% of
  • Colorectal and Pancreatic cancers

Also:

  • Gastric carcinoma
  • Breast carcinoma
  • Medullary thyroid carcinoma
9
Q

PSA

A
  • BPH, Prostatitis

- Prostate adenocarcinoma

10
Q

S-100

A
  • Neural crest origin:
  • Melanoma
  • Neural crest tumor
  • Schwannoma

Not neural crest:
-Langerhans cell histiocytes

11
Q

TRAP

A

Hairy cell leukemia (B-cell neoplasm)

12
Q

Bambesin

A
  • Adrenal neuroblastoma
  • Lung cancer
  • Gastric cancer