Tumor suppressor genes Flashcards by danica francisco

Q

Rb

A

chr 13; Retinoblastoma, Osteosarcoma

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Q

BRCA1 and BRCA2

A

chr 17q and 13q; Breast and Ovarian Cancer

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Q

p53

A

chr 17p; Most human cancers, Li-Fraumeni syndrome

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Q

p16

A

chr 9p; Melanoma

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Q

APC

A

chr 5q; Colorectal cancer (assoc with FAP)

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Q

WT1

A

chr 11p; Wilm’s tumor

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Q

NF1

A

chr 17q; Neurofibromatosis type 1

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Q

NF2

A

chr 22q; Neurofibromatosis type 2

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Q

DPC

A

chr 18q; Pancreatic cancer

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Q

DCC

A

chr 18q; Colon cancer

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