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Tumori Flashcards

1
Q

Etiopatogenie osteosarcom

A

Retinoplastom 7%
Iradiere
Complicatii boala Paget

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2
Q

Forme histologice de osteosarcom

A 
Osteoblastic 45%
Condroblastic - 27%
Anaplastic - 17%
Fibroblastic - 9%
Teleangiectazic - 1%
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3
Q

Incidenta crescuta metastaze osteosarcom in ce tesuturi

A

Alte structuri osoase
Pulmonar

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4
Q

Predominanta sarcom Ewing

A

Oase membre inferioare
Pelvis

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5
Q

Sarcom Ewing la coloratie PAS se observa

A

Glicogen crescut

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6
Q

Semne prognostic rezervat sarcom Ewing

A

Febra
Leucocitoza
VSH crescut
Anemie

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7
Q

Metastaze sarcom Ewing

A

La distanta
Plamani
Vertebre

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8
Q

Platoul palatoalveolar poate fi afectat de formele de tip

A

Carcinomatos
Sarcomatos

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9
Q

TU maligne de mezostructura invadeaza in peruoada de stare

A

Vestibul
Mucoasa jugala
Mucoasa palatina

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10
Q

TU maligne mezostructura in perioada de stare - aspect ulcerovegetsnt cu tendinta de invazie ptogresiva spre

A

Foze nazale
Orbita
Spatiu pterigomaxilar
Baza craniu

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11
Q

TU suprastructura invadeaza

A

Orbita
Sinus
Fose nazale

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12
Q

Semne oculare TU suprastructura

A

Diplopie
Exoftalmie
Scadere acuitate vizuala/amauroza

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13
Q

TU surpastructura se exteriorizeaza la nivelul

A

Pleoape
Unghi intern orbita

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14
Q

Elemente structurale ganglioni limfatici

A

Capsula conjunctiva
Arie corticala
Arie paracorticala
Aria medulara

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15
Q

DG# adenopatie cervicala metastatica

A 
TU benigne Ce
TU maligne Ce nemetastatice
Infectii regiune Ce
Adenopatii din hemopatii maligne
Adenite inflamatorii si/sau imuno
Afectiuni congenitale
Alte cauze
Structuri normale
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16
Q

Medicamente din limfadenite medicamentoase

A 
Penicile
Strepto
Sulfonamide
Meprobanat
Heparine
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17
Q

Factori de risc recidica keratochisturi

A 
Neindepartare chist monobloc
Keratochist odontogen primordial
Dimensiune mare
Multiloculare
Keratochisturi care au erodat corticalele
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18
Q

Ameloblastomul poate avea origine in

A

Resturile lamei D Serres
Organul adamantin
Epiteliul unui chist odontogen - derivat din tesuturi Malassez
Strat bazal al mucoasei orale

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19
Q

La copii, keratochistul odontogen este parte din

A

Sindromul nevic bazocelular

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20
Q

KO primordial deriva din

A

In locul unui dinte
Resturile Serres
Celulele bazale ale epiteliului oral

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21
Q

KO dentiger deriva din

A

In jurul unui dinte

Epiteliul adamantin redus

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22
Q

Semne clinice indirecte chist periapical

A

Ssb la Pe in axul D
Jena dureroasa la Pa in V bucal, in dreptul D

23
Q

Ameloblastom extraosos periferic - etiopatogenie

A

Resturi lama dentara Serres
Epiteliu bazal mucoasa orala

24
Q

Rata recidive ameloblastoame

A

Intraosos solid multichistic - 15-20%
Intraosos unichistic - 10-20%
Extraosos periferic - relativ scazuta

25
Cele mai frecvente chiste odontogene
Radiculare inflamatorii Periapical Radicular lateral Rezidual
26
Al doilea cel mai frecvent chist
Folicular dentiger 20% din chisturile de dezvoltare 20% din chisturile odontogene
27
Patogenie chist dermoid
Transformare chistica a incluziunilor epiteliale restante de la locul de unire a arcurilor brahiale pe linia mediana
28
Patogenie chist branhial
Incluzia epiteliala a unui pliu endodermic al celei de-a 2a fanta labiala Mecanism etiologic diferit de cel al canalului tireoglos
29
Localizari posibile chist dermoid
1. Tipic - chist dermoid oral, planseu, deasupra milohioidianului, pe linia mediana 2. Planseu bucal, paramedian 3. Sub milohioidian - chist dermoid suprahioidian 4. Extins din planseu in loja submentoniera 5. Foarte rar - limba, median 6. Foarte rar - loja SBM
30
Granulom periferic cu celule gigant - forme
Sesila | Rar pediculata
31
Tip crestere papilom oral
Exofitica, verucoasa, conopidiforma
32
Forme papilom oral
Pediculat | Uneori sesil
33
Variante histopatologice papilom sino-nazal
Papilom scuamos Papilom inversat - 15% risc malignizare Papilom cu celule cilindrice
34
Tipuri de HPV in papiloame orale
2 6 11
35
Cele mai frecvente localizari TU carcinomatoase orale
1. limba 2. planseul bucal
36
TU maligne ale mucoasei gingivale - secundare unor procese TU de vecinatate
1. mucoasa jugala 2. comisura intermaxilara 3. planseu bucal 4. fbm P 5. TU endosoase in faza de exteriorizare
37
Granulatiile galbui Trelat specifice
ulceratiilor tuberculoase - perilezional
38
Evolutie TU maligna buza
dupa depasirea etapei locale: 1. adenopatie metastatica loco-regionala 2. afectare osoasa de vecinatate 3. metastaze la distanta invazie si extindere: 1. parti moi labio-geniene 2. vestibul bucal 3. arc osos mentonier - afectarea osoasa madndibulara are loc in special in cazul evolutiei TU pe fata mucozala a buzei
39
TU maligna limba - localizare
- margine laterala - fata ventrala - sant pelvilingual mai rar - fata dorsala, varful limbii
40
TU maligna planseu - localizare
- paramedian in portiunea anterioara - sant amigdaloglos - in localizarile posterioare
41
TU maligna planseu si limba se extinde spre
1. amigdale 2. val palatin 3. mandibula - in formele pelvilinguale
42
Invazie nervoasa TU maligne limba si planseu
1. lingual 2. glosofaringian - uneori
43
Caracteristici Rx osteosarcom
1. arici 2. os pieptanat 3. perna cu ace 4. raze de soare 5. triunghiurile lui Codman
44
Etiopatogenie Osteosarcom
1. retinoplastom - 7% 2. boala Paget 3. iradiere
45
Histopatologie Osteosarcom
asociere de: - plaje celulare sarcomatoase fuziforme - neoformare tesut osos - matrice osteoida in functie de tipul celular predominant - forme histopatologice: 1. osteoblastic - 45% 2. condroplastic - 27% 3. anaplastic - 17% 4. fibroblastic - 9% 5. teleangiectazic - 1%
46
Aspect Rx carcinoame odontogene in functie de evolutie
1. rapida - Rtransparenta difuza, cu margini zimtate, neregulate 2. lenta - Rtransparenta relativ bine delimitata
47
TU maligne de mezostructura - au punct de plecare
1. mucoasa sinus maxilar 2. extindere TU din infrastructura 3. extindere TU din tegumente etaj mijlociu al fetei
48
Evolutie TU maligne buze - cai afectare osoasa mandibulara
directa: 1. invazie os din aproape in aproape 2. cu extensie ulterioara de-a lungul canalului mandibular 3. cu implicare PVN indirecta: - adenopatie SBM secundara, fixata - efractioneaza initial periostul - invadeaza apoi corticala osoasa
49
Ce ganglioni sunt implicati in TU maligne de limba si planseu
1. retrodigastric - Kuttner - portiune posterioara limba 2. supraomohioidian - Americani - portiune anterioara limba + planseu bucal anterior
50
Carcinoamele odontogene se pot dezvolta prin:
1. transformare maligna ameloblastom 2. direct din tesuturile epiteliului odontogen = carcinoame osoase primare 3. din membrana epiteliala a chisturilor odontogene
51
Sistemul limfatic
1. capilare limfatice 2. vase limfatice 3. trunchiuri colectoare 4. ganglioni limfatici
52
Modificari ale ganglionilor limfatici in context onco
1. Hplazie foliculara 2. Hplazie corticala 3. Histiocitoza sinusala - multe histocite
53
Factori care influenteaza diseminarea metastatica a TU primare
1. localizare (ant
54
Evolutia adenopatiilor clinice Ce
1. invazie si ruptura capsula ganglionara 2. fixare ganglionara 3. invazie structuri de vecinatate - tegument, vase, structuri osoase

Chirurgie (8 decks)

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