Tumors of Bone and Soft Tissue

Question 1

What is the first Rule of bone tumors?

Answer 1

Metastatic tumor is the most likely answer

Question 2

Types of Metastatic disease (lytic vs Sclerotic)

Answer 2

Sclerotic- stimulating osteoblasts (Prostate metasteses)

Lytic- stimulate osteoclastic bone resorption

Question 3

Osteoma

Answer 3

solitary slow growing tumor on or inside the skull and facial bones.

made of mature lamerllar bone. (ivory osteomas)

Question 4

Osteoid Osteoma

Answer 4

less than 2 cm.
occurs in teens and young adults
occur in long bones (usually femur)
pain responds to aspirin

Question 5

Osteoblastoma

Answer 5

Larger than 2 cm
involve the spine
pain is unresponsive to aspirin

Question 6

Osteochondroma

Answer 6

Cartilage capped tumor attached by a bony stalk to the underlying skeleton
only in endochondral bones
slow growing and asymptomatic

Question 7

Endochondroma

Answer 7

Benign neoplasms of hyaline cartilage.

Question 8

Chondrosarcoma

Answer 8

Produces exclusively cartilage.

Painful enlarging mass.

Question 9

Ewing sarcoma

Answer 9

Primitive neuroectodermal tumors
Aggressive malignancy
Translocation t(11;22)
layers of reactive bone deposited in an “onion skin”

Question 10

Giant Cell Tumors

Answer 10

Osteoclastoma of the epiphysis with lytic lesions and soap bubble appearance.