Type 2 Diabetes Drugs

Question 1

Classes of Type 2 Drugs

Answer 1

Sulfonyureas Meglitinides Biquinides

A - Gluconase Inhibitors Thiazolinediones Amlyn

Incretinmimetic

Question 2

Sulfonyureas

Answer 2

Meds: Glucotrol (glipizide) (PO)
Micronase (glyburide)

Action: ↑ production of insulin

Tell Pt: hold if blood sugar is ↓ in am and call MD

Question 3

Meglitinides

Answer 3

Meds: Prandin (repaglinide) (PO)
Starlix (nateglinide)

Action: ↑ production of insulin

Tell Pt: take 30 minutes before meals, skip if skipping the meal. Less risk of hypoglycemic reaction.

Question 4

Biquinides

Answer 4

Meds: Glucophage (metFormin) (PO)

Action: ↑ sensitivity to insulin

Teach Pt: if having IV w/contrast, hold for 2 days before, day of test, and 2 days after. Possibility of Renal failure, not for Pts. with renal problems.

***Less likely to cause weight ↑ than other Type 2 drugs.

Question 5

A - Gluconase Inhibitors

Answer 5

Meds: Precose (acarbose)
Glyset (miglitol)

Action: “STARCH BUSTER”
removes carbs, go into toilet, ↓ carbs absorbed in the intestines.

Question 6

Thiazolidinediones

Answer 6

Meds: Actos (pioglitizone) (PO)
Avandia (rosiglitazone)

Action: “ INSULIN SENSITIZERS” ↓ insulin resistance
Rare to see hypoglycemic reaction unless taken with other DM2 drugs.

***ALERT: can cause HF, do good heart assessments.

Question 7

Amlyn

Answer 7

Meds: Symlin (pramlintide) (SubQ)

SubQ with insulin, but not mixed together.

Question 8

Incretinmimetic

Answer 8

Meds: Byetta (exenatide) (SubQ)

SubQ, no insulin necessary

Action: ↑ insulin secretion

Question 9

TEACHING

If on _________________, can mask _______________ reaction. No_______________, right to ____________.

Answer 9

Beta Andrenergics
hypoglycemia
warning
coma

Question 10

TEACHING

If pt is taking ______________or _______________ BS ____. Frequently will need ___________ ___________ temporarily.

Answer 10

loop diuretics
prednizone
↑
insulin injections