Typhoid Fever Flashcards

1
Q

Why typhoid mimic appendicitis?

A

RIF pain and coated tongue

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2
Q

Pathogenesis of typhoid?

A

Osmosis

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3
Q

Org and method of transmission of typhoid?

A

Salmonella typhi, salmonella paratyphi A,B,C

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4
Q

Clinical features of typhoid?

A

1st week- slow rising temp+relative bradycardia, malaise,headache(frontal) ,cough,coated tongue, constipation, +blood culture

2nd week- high fever( step ladder ,could be there in w 1 also) , diarrhea,rose spots, hepatosplenomegaly, stool culture +, widal reaction strongly + to anti O and H ab

3rd week- intestinal hemorrhage and septicemia, peritonitis, encephalitis, metastatic abscess, colecystitis, endocarditis, urine culture +

BM suppression also could occur

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5
Q

Ix?

A
1.cultures 
Blood-1st week 
Stool-2nd w 
Urine-3rd w 
2. Serology-SAT (standard agglutination test/widal test) 
Not very reliable 
Check for Ag H or O
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6
Q

Tx?

A
Ceftriaxone/cefotaxime
Ciprofloxacin 
Co-amoxiclav 
Chloramphenicol 
Cotrimazole
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