Undernutrition Flashcards

(79 cards)

1
Q

What is undernutrition?

A

Undernutrition is a lack of energy/nutrient intake to maintain health/ meet demands/ maintain homeostasis.

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2
Q

What is the current prevalence of undernutrition in the UK?

A

(BAPEN, 2018)
* 3 million people malnourished
* Elderly (>65) most affected, 1.3 million
*30-42% of patients admitted to care homes at risk
*25-34% of patients admitted to hospital at risk
*18-20% of patients admitted to mental health units at risk
*10-14% in sheltered housing at risk

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3
Q

Name some of the signs of undernutrition

A

Signs of undernutrition
* Weight loss (doesn’t always occur)
* Muscle strength loss
* Dry, thin, brittle hair
* Cracked/ dry nails
* Xerosis (dry skin)
* Loose/poor fitting dentures
* Loose/poor fitting clothes/jewellery
* Reduced appetite
* Lack of interest in food/drink
* Tiredness/Lethargy
* Falls
* Dysphagia
* Prolonged wound healing
* Reduced ability to perform normal tasks
* Poor concentration
* Poor growth in children
* Mood changes: depression

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4
Q

Scientific

What are the 5 causes of undernutrition?

A

The 5 causes of undernutrition (scientific)
* Decreased dietary intake
* Increased nutritional requirements/metabolic demands
* Impaired nutrient absorption
* Impaired nutrient utilization
* Excessive loss of nutrients

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5
Q

What are the 12 main causes of decreased dietary intake?

A

12 main causes of decreased dietary intake:
* Modified consistency diets
* Food neophobia: particularly in small children & older adults
* Food insecurity
* Poor presentation, taste, flavour
* Lack of cooking knowledge
* Hospitals/care homes: foods that meet religious/cultural requirements not provided.
* Social isolation/loneliness
* Excess alcohol consumption
* Issues with mouth/swallowing
* Low mood
* Lack of assistance
* Interrupted meal times

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6
Q

What did **Capiola et al., 2016 **find about food neophobia and older adults?

A

Capiola et al., 2016 found that food neophobia was reported to significantly reduce the intake of 20 nutrients in older adults.

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7
Q

What did SACN, 2021 find about decreased energy intake?

A

SACN, 2021 found that:
* OAs aged 65-74 had lower energy intake than 19-64
* >/= 75 had lower energy intake than 65-74
* >/= 75 lower mean percentage protein intakes than 65-74
* Protein intakes per kg body weight were lower in older age groups

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8
Q

What are the 9 D’s?

A

The 9 D’s:
* Dentition
* dysgeusia (impaired sense of taste)
* dysphagia
* diarrhoea
* disease
* depression
* dementia
* dysfunction
* drugs
* dependency for eating

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9
Q

What did Nieuwenhuizen 2010 find about environmental factors and dietary intake?

A

Nieuwenhuizen 2010 found that environmental factors can increase or decrease dietary intake.

Increase dietary intake:
* Consistent meal times
* Eating with others
* Encouragement from care givers
* Easy access to food
* Eating whilst watching TV

Decrease dietary intake:
* Living alone
* Social isolation
* Unprotected/interrupted meal times
* Lack of assistance
* Inappropriate meal times

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10
Q

________________ adults need more _____________ than _______________ adults

A

Older adults need more protein than younger adults

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11
Q

Which age group (s) are more vunerable to the impact of low intakes?

A

Babies and infants are more vunerable to the impact of low dietary intake as they lack the same storage as adults (Langley-Evans, 2021)

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12
Q

Three main states that there is increased demand?

A

Three main states that there is increased demand:
* Trauma
* Pregnancy
* Lactation

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13
Q

Conditions with increased demand
(Lecture slides)

A

Conditions with increased demand:
* Neurological conditions (e.g. Parkinson’s)
* Chronic conditions (e.g. cancer)
* Pressure sores/wounds
* Wound healing/recovery
* Disease

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14
Q

In which conditions is malabsorption an independent risk factor for weight loss and undernutrition?

A

Malabsorption is an independent risk factor for weight loss and undernutrition in:
* Intestinal failure
* Abdominal surgical procedures

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15
Q

Which types of conditions can increase risk of undernutrition?

A

Gastroenterological conditions can increase undernutrition risk due to malabsorption caused by inflammation.

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16
Q

Excessive nutrient loss occurs via:

A

Excessive nutrient loss occurs via:
* Vomiting
* Diarrhoea
* Enterocutaneous fistulae
* Burns
* Excess diuretic use

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17
Q

What is the cost of undernutrition to the NHS?

A

Undernutrition costs the NHS £23.1 billion

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18
Q

What are the consequences of undernutrition?

A

Consequences of undernutrition:
* Weight loss
* Muscle loss: cardiac, respiratory
* Stunted growth
* Diminished functioning of GI tract: poor muscle and Villi function, enteropathy> increased likelihood of toxin entry >poor absorption & poor function
* Reduced immune function
* Poor wound healing
* Low Mg, K, Phosphate. High sodium & water> refeeding syndrome risk
* Depression
* Poor thermoregulation
* Pressure sores/ulcers

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19
Q

When does starvation lead to death?

A

Starvation > death
* 40% weight loss in acute starvation
* 50% in prolonged starvation
* obese individuals: 65-80% weight loss

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20
Q

How can loss of muscle mass be detected?

A

Loss of muscle mass can be detected with the grip strength test.

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21
Q

Describe the Malnutrition Carousel (BAPEN, 2018)

A

The Malnutrition Carousel (BAPEN, 2018)
* 24%-34% of hospital admissions at risk of undernourishment
* People who are malnourished/at risk have: longer stays, are more likely to need care and support upon discharge
* 70% of patients weigh less when they are discharged
* GP visits, hospital admissions, prescriptions increase

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22
Q

What can cardiac failure cause?

A

Cardiac failure can cause cachexia.

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23
Q

What is a pressure ulcer/sore?

A

Pressure ulcer/sore:
* Area of damaged skin & underlying tissue
* Caused by consistent pressure on area

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24
Q

What are the causes of pressure sores?

A

Pressure sore causes:
* Sustained pressure on skin
* Friction
* Shearing force
* Increased temperature/moisture (sweating?)

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25
How many stages are there of pressure sores?
There are 4 stages of pressure sores
26
What is the prevalence of pressure sores in hospitals?
Pressure sore prevalence * Physical disability 85% * Critically ill 33-53%, * Orthopaedics 19-30% * Hospitalized patients 3-23%, *
27
What is the role of undernutrition pressure sore development?
Role of undernutrition pressure sore development * Reduced nutrient supply> reduced energy metabolism> reduced maintenance and repair * Increased weakness> reduced mobility> increased pressure * Increased oedema> reduced tissue blood flow> ischaemia * Weight loss> prominent bones> increased sensitivity to pressure
28
Can obese/overweight people be undernourished?
Yes. Obese or overweight people can be undernourished
29
What is sarcopenia?
Sarcopenia is defined as loss of muscle mass, strength and function.
30
How is undernutrition defined? (NICE 2006)
Undernutrition is defined by: * >5% unintentional weight loss in 3 months * > 10% unintentional weight loss in 3-6 months * BMI < 20 kg/m2 + unintentional weight loss > 5% in 3-6 months
31
Should older people have lower or higher BMIs for survival?
Older people should have higher BMIs for optimal survival. (Cederholm 2015)
32
According to Stratton et al., 2003, BMI <18.5 kg/m2 is associated with?
According to Stratton et al., 2003, BMI <18.5 kg/m2 is associated with: * Increased frequency of illness * Reduced ability physical work capacity
33
What are the characteristics associated with >5% weight loss?
Characteristics associated with >5% weight loss: * Less energetic * Reduced voluntary activity *Fatigue
34
What are the characteristics associated with >10% weight loss?
Characteristics associated with >10% weight loss * Disturbances in thermoregulation * Poor response to surgery and chemotherapy
35
Is poor nutritional intake a part of the malnutrition defining process?
Poor nutritional intake is not part of the process for ‘defining’ malnutrition, but it can help to assess risk.
36
What is refeeding syndrome?
Refeeding syndrome is the electrolyte/fluid shifts that occur following the introduction of nutrition in a malnourished individual. Electrolyte and fluids are imbalanced.
37
Which electrolytes are affected in refeeding syndrome?
Phosphate, potassium and magnesium are affected in refeeding syndrome.
38
According to WHO how many adults are undernourished worldwide?
According to WHO (2021) 462 million adults are undernourished worldwide.
39
What is wasting?
Wasting: Low weight for height
40
What is stunting?
Stunting: low height for age
41
Various studies have found an increase in the frequency of illness amongst people with BMIs of ____
Various studies have found an increase in the frequency of illness amongst people with BMIs of **less than 20 kg/m2**
42
If someone has a BMI of less than ____ malnutrition is considered probable
If someone has a BMI of less than **18.5** malnutrition is considered probable
43
With a BMI of ____ malnutrition is possible with unintentional weight loss
With a BMI of **18.5-20** malnutrition is possible with unintentional weight loss
44
BMI cut offs are higher with _______ _________
BMI cut offs are higher with **weight loss**
45
Is nutritional intake a part of the malnutrition defining process?
No, nutritional intake is not a part of the malnutrition defining process. It helps to assess if someone is at risk.
46
In relation to nutritional intake, when do we wonder if someone is likely to become malnourished?
NICE 2006: ‘where a patient ‘has eaten little or nothing for more than 5 days and/or is likely to eat little or nothing for the next 5 days or longer’
47
Which vitamin may be deficient in refeeding syndrome?
Thiamine may be deficient in refeeding syndrome
48
Describe the pathophysiology of Refeeding Syndrome
**Refeeding syndrome pathophysiology** 1. Starvation: Catabolism dominates: Glucagon secretion increased. Glycogen (glycogenolysis), protein degradation & fat (lipolysis/ beta oxidation). Increased gluconeogenesis. 2. Depletion of macronutrient stores, protein, minerals, electrolytes 3. . Refeeding (nutrition introduced) 4. . Insulin increased> anabolic pathways increase 5. . Increased: glucose uptake, electrolyte uptake, micronutrient utilization (thiamine), protein synthesis, glycogenesis. 6. Electrolytes and micronutrients utilized faster than they can be replaced> refeeding syndrome 7. . Severe deficiency: Hypokalaemia, Hypomagnesaemia, Hypophosphataemia, Thiamine deficiency, salt and water retention: Oedema 8. Imbalance of electrolytes: heart, nervous system and organ failure.
49
What might hypokalaemia lead to?
Hypokalemia may lead to cardiac arrhythmias or weakness, fatigue, paralysis, hypoventilation, respiratory distress, and metabolic alkalosis
50
What might hypophosphataemia lead to?
Hypophosphataemia may lead to: decreased cardiac contractility and arrhythmias. Increase haemoglobin'saffinity for oxygen> decrease oxygen release to the tissues; acuterespiratory failure.
51
What might hypomagnesemia lead to?
Hypomagnesemia may lead to: exacerbated hypokalemia, neuromuscular symptoms and depression
52
What might thiamine deficiency lead to?
Thiamine deficiency might lead to: lactate accumulation, Wernicke's syndrome, Korsakoff syndrome and cardiac dysfunction.
53
What are the consequences of starvation?
**Consequences of starvation** * Decreased insulin and increased glucagon secretion * Glycogen stores depleted * Free fatty acids and ketones replace glucose as energy source (adipose tissue activated> fatty acids released) * BMR decreases * Brain adapts to using ketones * Atrophy of all organs * Reduced lean body mass * Abnormal liver function * Deficiency of vitamins and trace elements * Whole body depletion of potassium, magnesium and phosphate * Increased intracellular and whole body sodium and water * Impaired cardiac, intestinal and renal reserve, leading to inability to excrete excess sodium and water * Serum concentrations of electrolytes maintained within normal limits
54
What are the 4 triggers of refeeding syndrome?
4 refeeding syndrome triggers: 1. A switch from fat to carbohydrate metabolism 2. Increased insulin release 3. Increased uptake of glucose, phosphate, potassium, magnesium and water into the cells 4. Synthesis of lean tissue
55
What do the refeeding triggers lead to?
The refeeding triggers lead to: 1. Fluid retention 2. Low serum levels of potassium, magnesium, phosphate 3. Cardiac, respiratory, neuromuscular, renal, metabolic, hepatic and GI problems 4. Vitamin deficiency (thiamine)
56
Low level of potassium
<3.2 mmol/L (Brown et al., 2015)
57
What is Mg a co factor for?
Mg is a co factor for ATP
57
___________ reverses negative nitrogen balance via suppression of gluconeogenesis and reduced amino acid usage
**Glucose **reverses negative nitrogen balance via suppression of gluconeogenesis and reduced amino acid usage
58
What can excess glucose lead to?
Excess glucose can lead to: Hyperglycaemia Reduced sodium and water excretion Increased cellular thiamine utilisation due to its role as a co-factor for carbohydrate metabolism
58
NICE 2006 guidelines to recognise if someone is at risk of refeeding syndrome
NICE 2006 guidelines for refeeding syndrome risk: **At risk:** * Little or no food for >5days **High risk**: 1 or more of the following: * BMI < 16KG/M2 * Unintentional weight loss > 15% in 3-6months * Little or no food for > 10 days * Low K, Mg or Phosphate prior to feeding ** High risk:** 2 or more of the following: * BMI <18.5 kg/m2 * Unintentional weight loss >10% in 3-6 months * Little or no food >5 days * History of alcohol abuse or drugs including insulin, chemotherapy, antacids or diuretics. **Extremely high risk** * BMI < 14 kg m2 * Low or no food for > 15days
58
What are the NICE 2006 **refeeding guidelines** for those "At risk"?
**NICE 2006 refeeding guidelines for At Risk** * 50% of total energy requirements for the first 2 days, * Full requirements of fluid, electrolytes, vitamins and minerals from day 1
59
What are the NICE 2006 refeeding guidelines for those "High risk"?
**NICE 2006 refeeding guidelines for High Risk** * 10kcal/kg increased slowly to meet requirements after 4-7 days * Monitor fluid, K, P, Mg * Give thiamine and multivitamin
60
What did Baldwin & Weekes 2012 find when comparing dietary counselling with usual care and ONS?
Baldwin and Weekes 2012 found that comparing dietary counselling with usual care and with ONS, had no effect on mortality but did increase weight –mean 1.7 kg.
61
What did Beck et al. 2014 find about the addition of a dietitian to the discharge team?
Beck et al., 2014 found that the addition of a dietitian to the discharge team reduced hospital admissions and increased oral intake.
62
How much protein should elderly patients be having?
Elderly adults should have: Between 1.0 and 2.0 g/kg/day or higher (depending on health status e.g. severity of disease and risk of malnutrition) (ESPEN, 2019)
63
What are the fluid requirements for 18-60 year olds?
18-60 year olds need 35 ml/kg
64
What are the fluid requirements for >60 year olds?
>60 year olds need 30ml/kg
65
What are the other considerations for fluid requirements?
Other fluid requirement considerations: * Add 2-2.5 ml/kg for each degree rise in temperature above 37 * Assess additional losses from wounds and diarrhoea individually
66
Estimating energy requirements for adults
1. Population: Age based EAR for BMI of 22.5. PAL:1.63 (SACN 2011) 2. Therapeutic diets: BMR: PAL: (Henry 2005) 3. Nutrition support: REE: PAL (PENG 2018)
67
What has hand grip dynamometry been associated with for assessment?
Hand grip strength has been associated with assessment of: * serum albumin * sarcopenia * malnutrition * Nutritional status and disease severity in adults with cystic fibrosis * Nutritional status in cancer
68
What is sarcopenia?
The presence of low skeletal muscle mass and either low muscle strength (e.g., handgrip) or low muscle performance (e.g., walking speed or muscle power); when all three conditions are present, severe sarcopenia may be diagnosed.
69
What are the 5 options for the Food Based Strategy?
**Food based strategy*** 1. Meal pattern e.g., regular meals 2. Snacks e.g., high energy + high protein snacks (flapjacks, custard, rice pudding) 3. Dietary advice to - choose energy dense foods - choose the best time to eat - opt for nutritious drinks - boost flavour and aroma of meals (especially with those who are consuming texture modified diets or have loss of taste and smell) -consider meal delivery services 4. Food fortification -adding extra calories to meals without increasing volume such as olive oil, cheese, cream, full-fat milk, skimmed milk powder, honey, jam and sugar. 5. Optimise appearance of foods (particular texture modified foods) use colourful plates to encourage food intake.
70
What did Smoliner et al. 2008 find about food fortification?
Smoliner et al. 2008 found that food fortification can increase protein intake, hand grip strength was maintained but was not significant.
71
What is used if the Food Based Strategy doesn't work?
If the Food Based Strategy doesn't work: * Oral Nutrition Supplements * Enteral nutrition * Patenteral nutrition * Tube feeding
72
How many calories/protein will a tablespoon of dried milk powder add?
1 tablespoon of dried milk powder: 55 calories, 5.5g protein
73
How many calories/protein will a tablespoon of ground almonds add?
1 tablespoon of ground almonds: 60 calories, 2g protein
74
How many calories/protein will a tablespoon of grated cheese add?
1 tablespoon of grated cheese: 40 calories, 2.5g protein
75
What did Mills et al. 2018 find about food fortification?
Mills et al., 2018 found that food fortification is: Effective, well‐tolerated and cost‐effective intervention to improve dietary intake amongst older inpatients
76
Environment considerations for undernutrion
**Environment considerations for undernutrion** * Social –number of people and better known will increase intake * Encouragement * Protected mealtimes * Ambiance * Timing