Unexplained Symptoms in Neurology Flashcards

1
Q

How should you approach neurological symptoms?

A

Is there something wrong with the nervous system?

If so:

  • Where is it? (symptoms etc)
  • What is it? (investigation)

Diagnosis:
-This predicts prognosis and management

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2
Q

Are unexplained symptoms common?

A

Yes. Extremely

Not just in neurology:

  • GP 50% patients
  • Neuro not quite that high
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3
Q

Give some examples of common unexplained symptoms

A
Poor memory
Poor concentration
Headaches
Altered sense of smell
Altered sense of taste
Tinnitus
Dizziness
Funny turns
fatigue
Weakness
Tingling
Pain
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4
Q

What are the two situations for unexplained symptoms?

A

Situation 1

  • Symptoms
  • No signs
  • Normal investigations
  • (No proof of any underlying pathology)

Situation 2

  • Symptoms severe
  • Abnormal signs seem minor
  • Abnormal investigations seem minor
  • (Known pathology fails to explain symptoms)
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5
Q

What are unexplained symptoms likely to be a disturbance of?

A

Mood
Emotion
Behaviour

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6
Q

Describe the sick role

A

Rights:

  • Exemption from normal social roles
  • Not held responsible for their condition

Obligations:

  • Should get well
  • Should accept medical advice
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7
Q

Describe illness behaviour

A
Symptom perception
Symptom significance
Communication
Consultation behaviour
Treatment compliance
Maintenance of usual activities
Mood
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8
Q

What did the Scottish Neurological Symptoms Study find in 2003?

A

Patients with “unexplained” symptoms were:

  • More likely to be not working
  • More likely to be receiving benefits
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9
Q

How may physical problems effect psychological problems?

A

Physical disease -> Psychological symptoms

  • HD causing behavioral disturbance
  • Cerebral lupus causing psychosis

Physical diagnosis -> Psychological reaction
-Depression after diagnosis of MS

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10
Q

How may Psychological problems effect physical problems?

A

Psychological disturbance -> increased physical problem (inc pain)
-Adverse left event triggers depression which worsens pre-existing migraine

Psychological disturbance -> unexplained symptoms
-Someone with chronic anxiety and depression complains of unexplained weakness and fatigue

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11
Q

What are some of the physical manifestations of anxiety?

A

Autonomic:
-e.g. sweating, palpitations, tingling, dizziness, nausea, diarrhoea, urinary frequency

Increased motor tone:
-e.g. trmor, muscle pain, tiredness, dysphagia

Hyper-vigilance:
-e.g. Irritability, poor concentration, insomnia, easily startled

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12
Q

What do physical manifestations of depression include?

A
Sleep
Weight
Appetite
Libido
Energy levels
Posture
Pain perception
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13
Q

What is hypochondriasis?

A

Preoccupation with disease

Fear of illness

Persistent belief of unidentified disease

Request for repeated reassurance

Request for repeated investigation

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14
Q

What is Somatisation disorder?

A
  • Example of “abnormal illness behaviour”
  • Chronic
  • Onset before 30
  • Multiple unexplained physical symptoms
  • Thick notes
  • Multiple hospital visits
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15
Q

What is Conversion disorder?

A
  • Used to be called “hysteria”
  • Loss of function of a body part
  • Signs mimic neurological disease
  • Inconsistent signs
  • Patient not conscious of mechanisms
  • Information from functional imaging
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16
Q

What is Malingering?

A
  • Rare (?)
  • Symptoms or loss of function
  • Signs may mimic neurological disease
  • Inconsistent signs
  • Patient conscious of mechanisms
  • Occurs in “institutions”
  • Related to compensation
17
Q

What is chronic fatigue syndrome?

A

-Chronic
-Multiple physical symptoms
(fatigue, arthralgia, myaligia etc)
-Worse after exertion
-Absence of a specific physical cause
-Causes uncertain
-Approx 70% have features of psychiatric diagnosis (depression, somatisation)

18
Q

How do you manage unexplained symptoms?

A
  • Exclude physical disease
  • Carry out essential investigations
  • Avoid repeated investigations
  • Psychiatric assessment
  • Consistent, multidisciplinary approach
  • Consider antidepressant drugs
  • Consider cognitive behavioural therapy