Unit 1. Lec 9-Development of Nervous System Flashcards
When does the central nervous system start forming and what occurs?
- 3rd week as (thicken ectoderm) the Neural plate in the mid-dorsal region in front of the primitive node.
- Its lateral edge soon elevate to form the Neural folds
List Week 3 Key features
Nervous system first appears
- Neural plate
- Neural groove
- Notochord+paraxial mesechyme
- Neural tube
- Neural crest
Where is the neural plate located?
What does the lateral edges become?
- In front of the primitive node
- Lateral edges become neural folds
What does notochord and paraxial mescenchyme cause?
- Ectoderm to form to the neural plate
What does the neural tube form?
CNS
What does the neural crest form?
Forms the PNS and ANS
At week 4, the neural plate forms what?
Forms the neural tube and neural crest cells
- Neural tube cells become: CNS
- Neural crest cells become: PNS and ANS
What does the 2/3 of the Neural plate+ Tube become (as far caudal as the 4th pair of somite’s)?
HIGH yield
Future brain
What does the Caudal 1/3 of the neural plate and tube become?
HIGH yield
Spinal cord
What gives polarity to the embryo?
Primitive steak
What the neural folds, they fuse opposite of _ someite’s forming the neural tube
4th-6th somite’s (midline)
What does the fusion of neural folds create?
How it is structured?
Forming the neural tube that is open at both ends
- Cranial/rostral neuropore
- Caudal neuropore
When does the Cranial/Rostral neuropore close?
HIGH yield
around 25 days
When does the Caudal neuropore close?
HIGH yield
Around 27 days
What happens during spinal cord development that will decrease the neural canal size?
Lateral walls of the neural tube thickens
