Unit 2 Flashcards

(63 cards)

1
Q

Micro tubule

A

Polymer of tubulin dimers. Key components of cilia and flagella. Helps cells withstand compression and maintain their shape. For the spindle apparatus which is important for cell division.

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2
Q

Micro filaments/Actin filament

A

Actin monomers. Reinforce the plasma membrane and organize proteins. Maintain the shape of the cell.

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3
Q

Intermediate filament

A

Provide cells with mechanical strength. Proteins that make up the intermediate filaments differ from one cell to another. Cable like structure and very resilient to stretch.

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4
Q

Tight junctions

A

Connects two cells in order to remove space between them

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5
Q

Gap junctions

A

Connections between cells that allows varies molecules and ions to directly pass through. Ex: sodium

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6
Q

DNA replication

A

Occurs in the nucleus and produces identical copies

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7
Q

DNA polymerase

A

Enzymes that create DNA molecules by assembling nucleotides

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8
Q

Double helix

A

Shape of DNA formed with anti parallel strands. Looks like a staircase

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9
Q

Antisense strand/Template strand

A

Serves as the source for the protein code

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10
Q

Sense (coding) strand

A

Compliment to the antisense strand and is the same as the new RNA strand synthesized from the antisense strand

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11
Q

5 prime end

A

Same for both DNA and RNA, contains the phosphate group

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12
Q

3 prime end

A

DNA containers hydrogen whereas RNA has a hydroxyl group

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13
Q

Leading strand

A

From 5’ to 3’ and is continuous replication

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14
Q

Lagging strand

A

From 5’ to 3’ and is replicated in fragments known as Okazaki fragments

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15
Q

Primer

A

Serves as a starting point for DNA synthesis because DNA polymerase requires an existing strand of nucleotides

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16
Q

Mutation

A

Occurs in DNA and is a permanent change in the nucleotide sequence

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17
Q

Silent mutations

A

Nucleotide substitution. Results in a different codon but the same amino acid forming from that codon.

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18
Q

Missense mutation

A

Different codon forms a different amino acid resulting in the replacement of an amino acid

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19
Q

Nonsense mutation

A

Creates a stop codon that terminates translation

Ex: UAG codon

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20
Q

Frameshift (insertion or deletion) mutation

A

Insertion or deletion of a nucleotide which results in a change of all the codons
Ex: cystic fibrosis where 3 nucleotides are deleted which results in a missing amino acid causing ion imbalances

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21
Q

Karyotype

A

Number and appearance of chromosomes in the nucleus

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22
Q

Chromosomes

A

Made up of DNA and proteins. Passed from parents to offspring. Includes your genetic makeup.

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23
Q

Gene

A

Region of DNA that encodes RNA or protein product and is responsible for phenotypic traits

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24
Q

Allele

A

Variant form of a gene. Humans are diploid because one allele is inherited from each parent.

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25
Genotype
An individual's collection of genes, or the inherited alleles
26
Phenotype
An individual's observable traits
27
Heterozygous
Two different alleles (dominant and recessive) | Ex: Bb
28
Homozygous
Two of the same allele (dominant or recessive) | Ex: BB or bb
29
Dominant allele
A trait that will appear in the offspring if one of the parents contributes it
30
Recessive allele
The second allele; only show their affect if the individual has two copies
31
Punnet square
Used to predict the outcomes of offspring of a particular cross
32
Test cross
Breeding of dominant individual and recessive individual in order to determine genotype
33
Phenotypic trait
Observable trait such as hair color, eye color
34
Law of Independent Assortment
Stating that when two or more characteristics are inherited, individual hereditary factors as sort independently during gamete production, giving different traits an equal opportunity of occurring together
35
Law of Segregation
During production of gametes, the two copies of each genetic factor segregate so that offspring acquire one factor from each parent
36
Mitosis
When cells divide into identical cells
37
Meiosis
Division of cells into 4 daughter cells that are not identical and are haploid (one set of chromosomes)
38
Somatic cells
Any cell in the body except for sperm and egg cells. They are diploid (2 sets of chromosomes).
39
Prophase
Mitosis- chromosomes condense and become visible. Micro tubules radiate to opposite poles. Meiosis- same thing but with crossing over present.
40
Metaphase
Mitosis- micro tubules attach to chromosomes at kinetochure and align in a position roughly equidistant from the two poles Meiosis- same but without separation of sister chromatids (due to crossing over)
41
Anaphase
Mitosis- sister chromatids separate and travel to opposite poles Meiosis- homologous chromosomes separate but sister chromatids remain together
42
Telophase
Mitosis- nuclear envelope reforms and chromosomes decondense (you have two identical diploid daughter cells)
43
Anaphase II (Meiosis II)
Sister chromatids separate and you have four genetically different haploid daughter cells
44
Cytokinesis
Physical process of cell division
45
Chromatid (Sister chromatids)
A chromatid is one copy of a chromosome joined to another chromosomes. Both copies are identical.
46
Homologous chromosomes
Similar in size and shape but not identical. Carry the same genes but not the same allele.
47
Gamete
Haploid germ cell that is able to produce a zygote
48
Crossing over
Exchange of genetic information between homologous chromosomes
49
Oocyte
A cell from which an egg develops
50
Polar bodies
Haploid cell formed during meiosis. Does unit have the ability to be fertilized.
51
Haploid
One set of chromosomes
52
Diploid
Two sets of chromosomes
53
Fertilization
Union of human egg and sperm
54
Zygote
Formed from fertilization of two gametes
55
The motor protein that causes sperm movement
Axonemal Dynein
56
Protein that supports the shape of micro villi
Actin
57
Kinesin
Movement of a vesicles toward the plasma membrane
58
Dynein
Movement of a vesicles away from plasma membrane
59
Mitosis spindle is composed of polymers of
Tubulin
60
Cell division cycle
M, G1, S phase, G2
61
Synapsis
When maternal and paternal homologous chromosomes exchange information
62
X-linked
Males get it from their mothers
63
Who can a woman inherit an X-linked condition from?
Both mother and father need to have it