unit 2 connective tissue Flashcards
(41 cards)
Consistency and blood supply of connective tissues?
Consistency varies: liquid, gel or solid
Good nerve + blood supply except in cartilage + tendons
where is the connective tissue derived from?
-adudant + widely spread
➢ Derived from MESENCHYME
FUNCTIONS of connective tissue (6)
Bind, support, repair + strengthen other tissues
➢ Protect + insulate internal organs
➢ Compartmentalise structures (muscles)
➢ Transport (blood)
➢ Storage:-energy reserves (adipose tissue)
-water + electrolytes in extracellular matrix
➢ Immune response
CELLULAR COMPONENTS (2)
➢ RESIDENT: -immature (blasts), mature (cyte)
➢ TRANSITORY: -Leucocytes, Macrophages, Mast cells, Plasma cells
Resident component= 1. MESENCHYMAL CELLS (3)
- pluripotent+ undifferentiated
- star like shape, exist during embryonic stages
- form dentine forming odontoblasts, pulp, periodontal ligament
Resident component=2. FIBROBLASTS (2)
- large flat cells star shaped, principal active cells of connective tissue
- produce fibres (collagen + elastic + ground
substance)
Resident component= 3.FIBROCYTES
- mature cells trapped within extracellular matrix + maintain connective tissue
Resident component= 4. MYOFIBROBLASTS
- modified fibroblasts, secrete collagen + contract, abundant in healing areas + periodontal ligament, participate formation of root of teeth
Resident component= 5. ADIPOCYTES
extra
OSTEOBLASTS/ CYTES
CHONDROBLASTS /CYTES
- Form adipose tissue.
- Each adipocyte is surrounded by net of reticular fibres.
- store triglycerides.
- find them beneath the skin and around internal organs such as heart and kidneys.
- Function: protection,
white + brown adipose tissue
white= energy store
thermoregulation =(brown adipose tissue).
TRANSITORY CELLS (5)
– Macrophages – Plasma cells – Mast cells – Neutrophils – Eosinophils ORIGIN: pluripotent cells in bone marrow
transitory cell origin?
pluripotent cells in bone marrow
extracellular matrix (2)
all good at resisting force
- collagen
- elastic
- reticular
- ground substance
collagen = compoisiton, function + location
–Composition: collagen I proteins.
–Function: provide strength and resistance to tension.+ Allow tissue flexibility.
–Location: bone, cartilage, tendons and ligaments.
-
Reticular = composition, function + location
–Composition: fine collagen fibrils (collagen III and glycoproteins).
–Function: support in blood+ lymphatic vessel walls. + network around cells such as adipocytes, nervous fibres, smooth/skeletal muscle fibres.
Location- Found in basement membrane
Elastic = composition, function + location
-Composition: elastin + fibrillin.
–Function: strength and elasticity.
–Location: skin, blood vessel walls, lungs.
GROUND SUBSTANCE= characteristic + composition
{ transparent, colourless + fills spaces between fibres+ cells}: water, salts, proteoglycans
•Composition: water + salts + proteins + proteoglycans
(polysaccharide 95% + protein)
GROUND SUBSTANCE POLYSACCHARIDES
–Main polysaccharide: glycosaminoglycans (GAG’s) :
GROUND SUBSTANCE (4) GAGS 1. Chondroitin sulfate
1•Chondroitin sulfate :
-provides support/adhesiveness to cartilage, bone, skin and blood vessels
GROUND SUBSTANCE (4) GAGS 2•Dermatan sulfate
2•Dermatan sulfate
skin, blood vessels, cardiac valves and tendons
GROUND SUBSTANCE (4) GAGS 3•Keratan sulfate
3•Keratan sulfate
bone, cartilage and cornea.
GROUND SUBSTANCE (4) GAGS 4•Hyaluronic acid
4•Hyaluronic acid:
- dense, viscous, slippery (antiseptic, hydrating)>
- brings cells together, maintaining their shape and lubricating them.
GROUND SUBSTANCE- ADHESION PROTEINS
–Adhesion proteins (fibronectins): join collagen fibers with ground substance
EMBRYONIC CONNECTIVE TISSUE
–Mesenchyme: tissue (4)
-all other connective tissue arise.
-Found exclusively in embryo+ foetus
-irregular.
•Semifluid ground substance contains reticular fibres.