UNIT 2: IMMUNIZATIONS & COMMUNICABLE DISEASES Flashcards
Vaccines stimulate the ______ to produce antibodies?
Immune system
Vaccines use the ____ antigens as disease but killed or weakened
Same
What happens after antibodies disappear after destorying antigens..
Memory cells are formed
Who decides what vaccines?
- Advisory committee on immunization practices (ACIP)
- Centers for disease control and prevention
- pink book
- Committee on infectious diseases
- American Academy of pediatrics
- Red book
Why vaccinate?
- Prevent infectious disease
- Society
- Decrease/eliminate certain infectious diseases
- heard immunity
- Potentaial for reemergence if we dont have enough of the population vaccinated
Other than vaccinations how else can we prevent infections?
- Immunization
- handwashing
- reduce cross-transmission of organisms
- follow isolation protcol
- infection control policies
- sneeze and cough etiquette
What do we need to know about active immunity?
gernalized
- Endogenous production of antibodies
- Takes weeks/months to develop
- Long-lasting
What are 2 ways to acquire active immunity?
- Survive infection
- Vaccination
Active immunity is actively formed by….
The persons own immune system in repsonce to an antigen
What should we know about passive immunity?
Generalized
- Antiboides given to a person
- Immediate protection
- Short-lived
- Most common- maternal/infant
True or false: Babies born at full term will have the same antibodies that mom has and it can protect the baby up to 1 year of life?
True
What are different types of antibody sources?
provide passive immunity
- Blood products
- any blood product… there are antibodies in it
- Immune globulin
- Taken from 1000 adult donors… has lots of different antibodies.
- Hyperimmune globulins
- High concentration of a spcecific antibodies
- Antitoxin
- Derived from an animal for example horses… so horse is vaccinated and then we will use the antibodies from them. Often times people will experience an adverse reaction to the horse protien.. which can cause serum sickness
What are 2 types of vaccines?
- Live attenuated vaccines
- Inactivated vaccines
What do we need to know about live attenuated vaccines?
- Weakened form of “wild” virus/bacterium
- Must replicate
- Blood products might affect the vaccine from replicating which effects its effectiveness
- Issues with effectiveness
- Damage to organism
- circulating antibody: anything that damages that live organism or interferes with the organisms ability to replicate affects its ability to protect.
- Specific handeling/storage
What are examples of live attenuated vaccines?
- Measles
- Mumps
- Rubella
- Varicella
- Rotavirus
- Intranasal influenza
What do we need to know about inactivated vaccines?
- Produced in a culture media
- Cannot replicate
- Multiple doses
- Less affected by ciruclating antibody
- Blood transfusions can be given at the same time since it doest effect
- Antibody titer diminishes over time
- Booster
What are examples of inactivated vaccines?
- Polio
- Hep A &B
- Rabies
- Influeza
- Acellular pertusis
- Human papillomavirus
- diphtheria
- Tetanus
- Pneumococacal
- Meningocococal
Why are move inactivated vaccines given more than once?
1st dose usually primes the immune system… we start gaining immunity after the 2-3 dose
What factors could cause vaccine failure?
- Age/maternal antibody
- dose
- route
- storage and handling
- nutritional status
- Coexisting disease
- genetics
What information do we need to gather in order to prep for vaccine administration?
- Immunization history
- Should be done at every visit
- Recommened schedule
- Screening
- For contraindications
- discuss benefits/risks
- VIS statements
- After care instructions
- education on s/s to expect and appropritate times to take tylenol and motrin
What are nursing considerations/communications in regards to vaccinations?
- Provide accurate user-friendly information
- Explain they are needed what is going to help prevent
- Parent is expressing concern for childs health
- Be genuine & Empathetic r/t parents concerns
- Avoid judgmental/threatening language
- Be knowledgable
- Give VIS before vaccination & Anwser question
- Be flexible
- Parents may want to spread out vaccines
- Involve parent in minimizing adverse effects
- Rescpect parents ultimate wishes
What documentation must we have for vaccinations?
- Day, month & year of administration
- vaccine manufacturer
- Vaccine lot number
- Name and title of person administering vaccine & Address of facility
- Vaccine information statement
- Route
- Site
- Informed concent
- Vaccine refusal
What are some important issues regarding vaccines?
- Spacing of vaccines
- Interval between doses of same vaccine
- timing of antibody-containing blood products
- Live Vaccines: If given to close together it can alter the effectiveness of the vaccine
- inactivated vaccines: not typically affected - Screening
- Idenitfy contraindications/precautions: usuing standardized screening forms
Allergy to vaccine or component is it contraindicated in live attenuated and/or inactivated?
Live: Contraindicated
Inactivated: Contraindicated