Unit 2: Intro and Electric Cardio Flashcards

1
Q

Blood flows throughout the body through ______

A

pressure gradients
high –> low pressure

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2
Q

Flow (Q) =

A

Q = ∆P / R

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3
Q

Poiseuille’s Law:

A

R = 8nl / πr^4

R ∝ 1/r^4

*Radius of blood vessel raised to the fourth power

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4
Q

Length and viscosity are typically _____

A

constant

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5
Q

velocity (v) =

A

v = Q / A

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6
Q

In the capillaries, cross-sectional area ______, therefore velocity of flow ____

A

increases, decreases

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7
Q

Velocity is _____ proportional to total cross-sectional area

A

inversely

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8
Q

If vessel A has a smaller cross-sectional area than vessel B, which has a greater velocity of flow?

A

vessel A
decreased A, increases v

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9
Q

Radius plays the greatest role in determining resistance because…

Radius can be ______
_____ and ______ are constants
Radius factors in the equation to the ____ power

A

regulated (can dilate and restrict)
Length, viscosity
4th

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10
Q

Series resistance:

Artery -> Arteriole -> Capillary -> Venule -> Vein

Total flow (Q) is _____
Pressure gradually _____

A

CONSTANT

decreases

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11
Q

Parallel resistances:

Q aorta ____ Q vena cava
Pressure difference is the _____ across all parallel

A

Q aorta = Q vena cava
same

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12
Q

Are left and right sides of heart in series or in parallel?

A

IN SERIES

Total flow rate should remain constant aka all the blood that enters the right should leave on the left

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13
Q

Flow remains ______ from aorta to capillaries

A

CONSTANT

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14
Q

Velocity of flow is lowest in the ______

A

capillaries

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15
Q

Arteriole A is 2x longer than arteriole B, but the radius arteriole B is 1/2 that of arteriole A. Which arteriole offers less resistance to flow?

A

Arteriole A

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16
Q

Decreasing radius, ______ resistance

A

increases

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17
Q

An artery branches into two arterioles. Suppose one dilates and the other constricts. What happens to flow in each arteriole?

A

Increases in dilates (radius gets bigger)
Decreases in constricts (radius gets smaller)

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18
Q

Pulse pressure (PP) =

A

PP = SBP - DBP

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19
Q

Autorhythmic cells produce electrical signals ______

A

on their own, don’t need an outside stimulus

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20
Q

Firing rate is determined by the fastest autorhythmic cell, which is usually the ______

Order (gets slower):
1.
2.
3.
4.

A

SA node

  1. SA node
  2. AV node
  3. Bundle of His
  4. Purkinje fibers
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21
Q

Pacemaker cells are _____ in orgin

A

muscle

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22
Q

In a neuron action potential, you need an outside stimulus that innervates the soma, producing a graded potential that is suprathreshold that reaches the axon hillock.

For pacemaker cells, however, there is no _______ needed because of ______ channels.

A

outside stimulus
If channels (funny channels)

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23
Q

If channels are activated at -60mV ______-polarized

A

hyperpolarized, not depolarized

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24
Q

When If channels open, increase permeability of BOTH ________. However ______ is greater than ______

A

Na+ and K+
Na+ going into the cell
K+ going out of the cell

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25
______ is responsible for the upstroke in pacemaker cells, whereas _____ is responsible in neurons
calcium (Ca2+), sodium
26
______ are the origin of the heartbeat
Pacemakers
27
If you had a pacemaker other than the SA node setting the pace, that would be called an ______
ectopic pacemaker
28
Just like in neurons, voltage gated _____ channels are needed for the upstroke in contractile cells
sodium
29
Difference between pacemaker and contractile? Upstroke?
Upstroke for pacemaker calcium Upstroke for contractile sodium
30
Calcium plateau represents calcium channels being open and competing with ______, giving enough time for calcium to go into cells to have a ______
potassium contraction
31
How do contractile cells depolarize to the threshold?
Pacemaker cells!
32
Contractile cells are syncytium, acts like one cell because of ______
gap junctions
33
________ controls force of contraction, whereas ______ controls rate of contraction
contractile cells pacemaker cells
34
Parasympathetic on pacemaker: ______ cAMP ______ K+ permeability ______ Ca2+ permeability _____ rate of depolarization, ______ heart rate
decrease increase decrease decrease decrease
35
Sympathetic on pacemaker: ____ cAMP _____ Na+ and Ca2+ permeability _____ rate of depolarization, ______ heart rate
increases increases (makes us reach threshold faster) increases, increases
36
The internodal pathways take the signal to the ______ and ______
atrial muscle AV node
37
Current flowing in heart produces a net vector =
average value of 60º from horizontal
38
Action potential is a _____ recording ______ reading ECG is a ____ of action potentials and electrical activity _____ reading
single cell intracellular SUM extracellular
39
_____ angle to lead = flat line
90º doesn't mean there's no activity
40
Overall strongest upward deflections produced by:
Lead II (PARALLEL) to electrical axis of the heart (60º) Upward Deflection (-) -> (+)
41
Segments are regions between two waves, indicated by _____ ex.
flat line P-R segment S-T segment
42
Interval includes at least one _____ and one ____ PR Interval: beginning of ____ to beginning of _____ QT interval: beginning of _____ to the end of ____
segment, wave P wave, QRS complex QRS complex, T wave
43
P wave is _____ depolarization the depolarization of ____ contractile cells
atrial
44
Cannot see depolarization of _____ cells on ECG (ex. SA node, AV node) because they are small but they do happen
pacemaker
45
PQ or PR segment: conduction through _____ and ______
AV node, AV bundle
46
Q and R wave: septal wall ______
depolarization
47
S wave: ventricle ______ Left ventricle is ______ than right ventricle
depolarization thicker
48
ST segment: electrically _____ allows for time for _____
neutral contraction
49
T wave: ventricle ______
repolarization
50
Lead I are two ______ to measure potential difference that connects RA to LA
two electrodes
51
Electrical events ______ mechanical or electrical events ____ mechanical events
PRECEDES initiate
52
The signal during the PR segment is in the _____
AV node
53
Where does the ventricular Ca2+ plateau coincide with the ECG?
ST segment
54
_____ determines the amplitude of the waves
Mass of the tissue
55
< 60 bpm =
bradycardia
56
> 100 bpm =
tachycardia
57
Heart rate = number of _____ / sec = x beats/60 sec
number of R-R intervals/ # of secs = x beats/60 sec
58
First degree heart block: Conduction ______ through ______ Distinguishing factor?
slowed , AV node Prolonged PR segment
59
Third degree (complete) AV block: ____ conduction through AV node P waves _______ from QRS complex SA node are the pacemaker for atriums, Purkinje are the pacemaker for ventricles (you see two different rhythms going on)
NO completely dissociated (a QRS does not always follow a P wave)
60
Distinguishing factor of atrial fibrillation?
No visible P waves, QRS NOT rhythmic
61
Distinguishing factor of ventricular fibrillation?
chaotic