Unit 3 Flashcards
(251 cards)
infection
- invasion of a susceptible host by pathogens or micro-organisms that cause dz
- can be localized or systemic
colonization
•micro-organim invades host, but doesn’t cause dz
nonspecific innate immunity
- native immunity that restricts or immediately responds to antigens
- skin, phagocytic cells, complement, inflammation, etc
- temporary
specific adaptive immunity
- allows body to make antibodies in response to specific antigens
- requires time
- provides permanent immunity
- B and T lymphocytes, immunoglobulins
communicable dz
•transmitted from one person to another
bacteriostasis
•prevention of growth and reproduction of bacteria
nature of infection
- symptomatic if pathogens multiply and cause clinical signs/symptoms
- asymptomatic if no clinical signs
- communicable if can be transmitted
- hand hygiene is most important to prevent spread
chain of infection
- ) causative agent- bac, vit, etc
- ) reservoir- host; tubing; food; flowers
- ) portal of exit- reap. tract, GI, GU, skin, blood
- ) mode of transmission- drop, air, contact
- ) portal of entry to host
- ) susceptible host
* organisms enter/exit thru same route
incubation
- 1st stage of infection
* interval b/t pathogen entering body and presentation of first symptom
prodromal stage
- 2nd stage of infection
- interval from onset of general symptoms to more distinct
- pathogen is multiplying
illness stage
- 3rd stage of infection
* interval when symptoms specific to infection occur
convalescence stage
- 4th stage of infection
- actue symptoms disappear
- total recovery may take days to months
normal flora
- natural defense against infection
- release antimicrobial substances
- inhibit multiplication of pathogens
inflammation
•natural defense against infection •vascular/cellular responses •exudates •tissue repair *histamine stimulates nerve endings and causes
serous exudate
•contains serum (liquid)
serum
•protein containing liquid part of blood that separates from platelets during coagulation
serosanguineous exudate
- contains serum and blood
* pinkish color
purulent exudate
•contains pus
sanguineous exudate
•contains blood
healthcare associated infection (HAI)
•infection acquired while receiving care in healthcare setting
•UTI/URI, wounds, and blood most common
•ICU most common source
*nosocomial infection
iatrogenic infection
•HAI resulting from a diagnostic or therapeutic procedure
exogenous HAI
- from microorganisms outside individual
- not normal flora
- Ex: salmonella
endogenous HAI
- pt’s flora becomes altered and overgrowth results
- result of broad-spectrum abx
- Ex: strep
developmental considerations of susceptibility to infection
- infant- immature immune response
- middle age- refined defenses
- older- cell-mediated immunity decline