Unit 4 - Blood System Flashcards Preview

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Flashcards in Unit 4 - Blood System Deck (47)
1

Function of blood

transport system for maintaining a constant environment for living tissues throughout body

2

Blood volume contains what 5 components?

1. plasma (liquid)
2. erythrocytes (RBC)
3. leukocytes (WBC)
4. platelets / thrombocytes
5. serum

3

erythrocytes

- RBC
- contain hemoglobin to carry O2
- formed in bone marrow
- live 120 days

4

leukocytes

Granulocytes - 3 kinds - most numerous
Agranulocytes - 2 kinds

5

Basophils

granulocyte
contain heparin (anticlotting) & histamine (released in allergic response

6

Eosinophils

granulocytes
increase in allergic responses
engulf substances that trigger allergies

7

neutrophils

granulocyte
- phagocytes that accumulate at sites of infection
- ingest & destroy bacteria

8

monocyte

agranulocyte
mononuclear
- get ride of cellular debris
- phagocytic that fight disease

9

lymphocyte

agranulocyte
- made in bone marrow & lymph nodes
- make antibodies

10

platelets

also: thrombocytes
blood cell fragments that help with clotting

11

erythropoietin

hormone secreted by kidneys that stimulates production of RBC in bone marrow

12

plasma

liquid portion of blood that contains:
- water
- dissolved proteins
- sugar
- wastes
- salts
- hormones
- and other substances

13

4 types of plasma proteins

1. albumin
2. globulin
3. fibrinogen
4. prothrombin

14

albumin

maintains proper concentration of water in blood

15

globulin

immunoglobins - antibodies that bind to and destroy antigens

16

fibrinogen

clotting protein

17

prothrombin

clotting protein

18

serum

- plasma minus clotting protein & cells
- clear, yellowish fluid that separates from blood when it clots

19

pancytopenia

deficiency of all 3 components (RBC, WBC, and platelets)

20

-cytosis

abnormal condition of cells
macrocytosis - condition of big cells

21

chrom/o

color
hypochromia - low concentration of hemoglobin in RBC

22

morph/o

shape
morphology - study of shapes, form

23

poikil/o

irregular; varied
poikilocytosis - irregularity in shape of RBC

24

spher/o

globe; round
spherocytosis - auto-hemolytic anemia (a disease of the blood) characterized by the production of RBCs that are sphere-shaped, rather than bi-concave disk shaped

25

blood dyscrasia

very broad term meaning any abnormal or pathologic condition of the blood

26

anemia

deficiency in erythrocytes or hemoglobin

27

aplastic anemia

failure of good cell production in bone marrow

28

pernicious anemia

lack of RBC due to inability to absorb vitamin B12

29

sickle cell anemia

hereditary; abnormal shape of RBC leads to inability to carry hemoglobin
sickle-shaped

30

hemolytic anemia

reduction in RBC due to excessive destruction

31

purpura

multiple pinpoint hemorrhages and accumulation of blood under skin
deficiency of platelets - thrombocytopenia
autoimmune

32

leukemia

"blood condition of white"
- disease of bone marrow where malignant leukocytes fill marrow and bloodstream
- classification due to which leukocyte is involved

33

thrombocytopenia

- deficiency of platelets in blood
- low production or increased destruction

34

PTT

Partial Thromoplastin Time
-platelet count
- test done when someone is on a blood thinner
- measures presence of factors involved in clotting

35

PT

Prothrombin time
- test of the ability of blood to clot
- test done when someone is on a blood thinner
- measures presence of factors involved in clotting

36

hematocrit

Hct
% of RBC in volume of blood

37

bleeding time

time required for blood to stop flowing from a tiny puncture wound
- normal = 8 min

38

coagulation time

time for venous blood to clot in a test tube
normal =

39

type A blood
1. can receive:
2. cannot receive

1. A, O
2. B, AB

40

Type B blood
1. can receive:
2. cannot receive

1. B, O
2. A, AB

41

Type AB blood
1. can receive:
2. cannot receive

1. AB, O, A, B
2. none

42

Type O blood
1. can receive:
2. cannot receive

1. O
2, A, B, AB

43

Rhesus factor

+ = have it (can get both + and -)
- = don't have it (can only get -)

44

where does hemoglobin go to get broken down?

spleen
liver
bone marrow

45

condition of bilirubin in urine?

bilirubinuria

46

BMT

bone marrow transplant

47

3 major ways for jaundice to occur:

1. excessive destruction of RBC (hemolysis)
2. blocked bile duct
3. damaged liver