Unit 5 Heredity 8-11% Flashcards

1
Q

Heredity

A

Passing of traits from parent to offspring.

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2
Q

Genes

A

DNA sequences that code for proteins + determine an organism’s traits → located on chromosomes (gene locus).

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3
Q

Homologous Chromosomes

A

Pair of chromosomes (one from each parent) that carry the same genes, but different alleles.
*NOT IDENTICAL

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4
Q

Mendel’s Experiment

A
  1. He studied seven traits, each with two distinct forms (tall vs. short, purple vs. white).
  2. He started true-breeding plants (homozygous dominant) → passed down the same trait when pollinated.
  3. Crossed two true-breeding plants with different traits → F1 generation (hybrids) were all purple.
  4. F1 generation self-pollinated → F2 generation traits were in a 3:1 ratio.
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5
Q

Mendel’s Understand of Alleles

A

Organism have two alleles for each gene (one from each parent) resulting in genetic variation.

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6
Q

Mendel’s Law of Dominance

A

When an organism has two alleles for a gene, the dominant allele is expressed & the recessive allele is hidden.

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7
Q

Mendel’s Law of Segregation

A

Only one allele is passed to offspring because the 2 alleles for a gene separate during meiosis.

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8
Q

Mendel’s Law of Independent Assortment

A

Alleles for different genes are passed down independently of one another because homologous chromosomes split during meiosis.

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9
Q

Genotype vs. Phenotype

A

Genotype: genetic makeup (AA, Aa, aa).
Phenotype: observable traits, determined by genotypes.

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10
Q

In Mendelian genetics, heterozygous dihybrid crosses result in a ______ ratio because of ______ and ______.

A

9:3:3:1, independent assortment, complete dominance.

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11
Q

Non-Mendelian: Incomplete Dominance

A

Neither allele is complete dominant → mix of parent phenotypes.
Ex. red & white flowers produce pink offspring.

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12
Q

Non-Mendelian: Codominance

A

Both alleles in a heterozygote are expressed → both traits displayed.
Ex. A & B blood type are codominant→ AB.

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13
Q

Non-Mendelian: Multiple Alleles

A

Genes have more than two alleles.
Ex. A, B, & O blood types.

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14
Q

Non-Mendelian: Polygenic Inheritance

A

Traits influenced by multiple genes → gradient of phenotypes.
Ex. hair/eye color & height

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15
Q

Non-Mendelian: Environmental Influence

A

Environment affects gene expression → variation in phenotypes (even if they have the same genotype).

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16
Q

Non-nuclear inheritance involves genes that are located on chromosomes ______ of the ______.

A

Outside, nucleus.

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17
Q

Mitochondrial & Chloroplast DNA

A

Randomly assorted into gametes → mitochondrial traits are determined by the mother.

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18
Q

Wild vs. Mutant Phenotypes

A

Wild: common form of a trait.
Mutant: variation caused by mutation; less.

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19
Q

Morgan’s Sex-linked Gene Experiment

A
  1. True-breed red-eyed female (wild) x white-eyed female (mutant) → F1 offspring had red eyes.
  2. Crossed red-eyed female x red-eyed male → all females had red eyes, but it was 50/50 for males.
  3. Gene for eye color is on the X chromosome.
20
Q

Non Mendelian: Sex-linked Genes

A

Traits are determined by genes located on the sex chromosomes (mainly X).

21
Q

How are sex-linked traits inherited in males vs. females?

A

Males: 1 X chromosome → if they inherit mutant allele it will show up.
Females: 2 X chromosomes → need two mutant alleles to show up.

22
Q

What are four ways to tell if a trait is sex-linked?

A
  1. More common in males.
  2. Trait skips generations in females, but shows up in sons.
  3. No male-to-male transmission.
  4. Daughters can be carriers.
23
Q

Morgan’s Gene-Linkage Experiment

A
  1. Crossed flies that differed in body color (gray vs. black) & wing type (normal vs. vestigial).
  2. He expected a 1:1:1:1 ratio by crossing BbBv (gray, normal) x bbvv (black, vestigial).
  3. More parental-types than recombinants.
24
Q

Non-Mendelian: Linked Genes

A

Genes located close together on the same chromosome tend be inherited together (do not assort independently).

25
Recombinant Frequency
Percentage of offspring that that display traits different from their parents due to crossing over during meiosis.
26
Diploid vs. Haploid Cells
Diploid: two complete sets of chromosomes → human somatic cells have 46 chromosomes (23 sets of 2). Haploid: single chromosomes → gametes have 23 chromosomes.
27
Fertilization
Male & female gamete cell fuse to create a zygote.
28
Meiosis
Cell division that produces four, genetically unique gametes with half the number of chromosomes.
29
Meiosis 1 vs. Meiosis 2
1: Homologous chromosomes separate → diploid to haploid. 2: Sister chromatids separate.
30
Before Meiosis, cells have ______ chromosomes and ______ chromatids.
46 & 92 → X shape.
31
Prophase I
1. Homologous chromosomes pair up to form a tetrad (four sister chromatids). 2. Crossing over: homologous chromosomes exchange DNA → unique combinations. 3. Nuclear envelope breaks down.
32
Metaphase I
1. Tetrads line up randomly at the metaphase plate. 2. Microtubules attach to the kinetochores of each chromosome.
33
Anaphase I
Pairs of homologous chromosomes are pulled to opposite poles, but sister chromatids remain attached.
34
Telophase I & Cytokinesis
Nuclear envelope forms around the daughter cells → each daughter cell is haploid, but each chromosome has 2 sister chromatids.
35
At the end of meiosis I, each of the 2 daughter cell has ______ chromosomes and ______ chromatids.
23 & 46 → X shape.
36
Prophase II
1. Chromosomes condense. 2. Nuclear envelope breaks down. 3. Spindle fibers begin to attach.
37
Metaphase II
Chromosomes line up at the metaphase plate.
38
Anaphase II
Sister chromatids separate & move to opposite poles.
39
Telophase II & Cytokinesis
Nuclear envelope forms around the separated sister chromatids & cell divides into two new haploid cells → 4 haploid cells.
40
After meiosis II, each of the 4 daughter cells have ______ chromosomes and ______ chromatids.
23 & 23 → / shape.
41
Chromosome Comparison Mitosis vs. Meiosis
Mitosis: 2 diploid cells with 46 chromosomes → 23 pairs of 2. Meiosis: 4 haploid gametes with 23 chromosomes, made of 1 chromatid → / shape.
42
Homologous chromosomes _______ during mitosis.
Do not pair up.
43
Which 3 processes contribute to genetic diversity?
1. Crossing Over 2. Independent Assortment 3. Random Fertilization
44
Nondisjunction
Chromosomes/sister chromatids fail to separate properly during meiosis, resulting in gametes with abnormal chromosome numbers (aneuploid) → genetic disorders.
45
What happens if nondisjunction occurs during Meiosis 1?
ALL daughter cells are aneuploid.
46
What happens if nondisjunction occurs during Meiosis 2?
HALF of the daughter cells are aneuploid.