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hscl 309 (pathology) > unit 5b > Flashcards

unit 5b Flashcards

1
Q
  1. SULPHONamides inhibit folic acid synthesis during b__ nucelotide production.
  2. SULPHONamides are used to treat bacterial c_.
  3. SULPHONamides __ the folate synthesis pathway
A
  1. bacterial
  2. conjunctivitis
  3. inhibits/blocks/stops
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2
Q
  1. SULPHONamides (e.g. BLEPH 10) can have these 2 adverse effects
  2. __ reactions
  3. S_ J_ Syndrome
A
  1. allergic
  2. Stevens-Johnson syndrome (painful rashes)
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3
Q

FLOROquinoLONES
1. inhibits _ _ _ synthesis
2. (increase/decrease) bacterial resistance
3. used for bacterial c_ and corneal u_

A
  1. DNA
  2. increase
  3. bacterial conjunctivitiis and corneal ulcers
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4
Q

FLOROquinoLONES adverse effects:
1. foreign body sensatino
2. __ or burning
3. conjunctival hyperemial

A

itching

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5
Q

FUSIDIC ACID
1. inhibits _ synthesis
2. gram (negative/positive)

A
  1. protein
  2. positive
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6
Q

Adverse effects of FUSIDIC ACID
1. stinging and i_
2. localized _ reaction

A
  1. itching
  2. allergic
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7
Q

AMINOglycoSIDES
1. inhibits _ synthesis
2. gram (negative/positive)
3. used to treat bacterial c_ or corneal u_
4. an example is (tobrex/tobradex)

A
  1. protein
  2. negative
  3. conjunctivitis / corneal ULCER
  4. tobrex
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8
Q

Adverse effects of AMINOglycoSIDES
1. Type _ delayed hypersensitivity
2. itching, r_, swelling

A
  1. FOUR
  2. redness
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9
Q

MACROlides
1. inhibits _ synthesis
2. gram (negative/positive)
3. used to treat bacterial c_

A
  1. protein
  2. positive
  3. conjunctivitis
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10
Q

Adverse Effects of MACROlides
1. _ vision
2. _ reaction

A
  1. blurred
  2. allergic
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11
Q

POLYpeptide Antibiotic
1. interferes with c_ w_ sythesis
2. gram (negative/positive)
3. used for (a) bacterial c_ and (b) bl_

A
  1. cell wall
  2. positive
  3. bacterial conjuctivitis BLEPHarrITIS
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12
Q

Adverse Effects of POLYpeptide Antibiotic
_ reaction

A

allergic

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13
Q

Combination Antibacterials
1. One example is GRAMicidin which interferes with cell m_
2. used for bacterial c_ and bl_ (which are types of bacterial infections)
3. contains (1, 2, 3, 4) antibiotics
4. they work by stopping or k_ bacterial

A
  1. cell membranes
  2. bacterial conjectivis and BLEPHarIITIS
  3. two antibiotics
  4. stopping or killing bacteria
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14
Q

Adverse effects of Combination Antibacterials
_ rection

A

allergic

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15
Q

ANTIVIRAL Drugs
1. used to treat h_ simplex
2. TOPICAL antivirals inhibits synthesis of viral _ _ _ (use 9x/day!)

A
  1. herpes
  2. DNA
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16
Q

Adverse effects of ANTIVIRAL Drugs
1. eye _
2. conjunctival r_
3. _ vision
4. punctate keratitis

A
  1. eye irritation
  2. redness
  3. blurred vision
  4. punctate keratitis
17
Q

Categories of ANTIfungals = PAA
1. polyenes
2. azoles
3. antiMETABOLites

A
  1. polyenes
  2. azoles
  3. antiMETABOLites
18
Q

POLYenes: a type of antifungals
1. are a c_ product
2. are effective agains y__
3. work by forming PORES in cell m_ and inhibiting the cell membrane function/

A
  1. compounded
  2. yeasts
  3. membranes
19
Q

AZOLES: a type of antifungals
1. work by inhibiting cell w_ synthesis

A

wall

20
Q

antiMETABOLITES: a type of antifungals that
1. inhibit d_ _ and r _ _ sythesis

A
  1. DNA and RNA
21
Q

General ANTIPARASITIC TREATMENT
is both l_ and d_

A

lengthy/long and difficult

22
Q

ANTERIOR SEGMENT
1. is a type of a_
2. has the shape of a r_ like corneal infiltrate
3. Can get from swimming , hot tub, c lens case
4. Can get from m in eyelash follicles or glands
5. Treated by tea tree oil or cliradex which alters cell m_

A
  1. antiparasitic
  2. ring
  3. pool
  4. mites
  5. membrane
23
Q

POSTERIOR SEGMENT
1. is a type of a_
2. treated by _ medications

A
  1. antiparasitic
  2. oral meds
24
Q

ARACHIdonic ACID
1. released from PHOSphoLIPid m_
2. causes i_

A
  1. membrane
  2. inflammation
25
Q

CORTICOsteroids
1. manmade
2. mimics the effects of c_
3. anti-inflammatory at (high/low) doses
4. immune suppression at (high/low) doses
5. inhibits the A_ (1, 2, 3, 4) enzyme

A
  1. cortisol
  2. low
  3. high
  4. A2
26
Q

CORTICOsteroids are used to treat
1. Iritis which is inflammation of the i_
2. conjunctivitis (manages the inflammation but (kills/doesn’t kill) the microbes
3. ocular a_
4. inflammatory d__ eye disease

A
  1. Iris
  2. doesn’t kill
  3. allergies
  4. dry eye
27
Q

Adverse effects of CORTICOsteroids
1. elevated IOP
2. c_ with longterm use
3. (delayed/quick) wound healing
4. (increased/decreased) risk of infection

A
  1. elevated IOP
  2. cataracts
  3. delayed
  4. increased
28
Q

NSAIDS
1. stands for Non S_ Anti Inflammatory drugs
2. acts on the ARACHIDONIC acid pathway
3. (inhibits/increases) COX pathways
4. used to treat P_ and inflammation after c_ surgery

A
  1. (non) Steroid
  2. acts on the ARACHIDONIC acid pathway
  3. inhibits
  4. pain, cataract surgery

hscl 309 (pathology) (6 decks)

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