Urinary System Flashcards
(44 cards)
What are the layers of the kidney
Cortex
Medulla
Pelvis
What is in the renal cortex
Glomeruli
PCT
DCT
What is a medullary ray
A collection of loop of Henle’s and collecting ducts that originate from the nephrons that have the renal corpuscle in the outer part of the cortex
Are there glomeruli in the renal medulla
No
What is the glomerulus supported by
Mesangial cells
What’s surrounds the glomerulus
Bowmans capsule
What is the basement membrane of the glomerulus lined by
Podocytes
What stain highlights the glomerular basement membrane
Periodic acid shciff
What do mesangial cells comprise
Smooth muscle
 Does albumin get filtrated out of the capillary lumen
No it’s too large
What is specific about the basement membrane of the glamorous
It’s a double basement membrane and it’s negatively charged
Where is the juxtaglomerular apparatus
Right next to the glomerulus
What do granular cells do
Detect blood pressure and secrete renin at low blood pressures
What does the juxtaglomerular apparatus contain
Granular cells and macula densa cells
What is glomerular tubular feedback
Where the macula densa cells detect sodium concentrations and feedback to the afferent arteriole
What is the proximal convoluted tubule lined by
Simple cuboidal epithelium
What is the border of proximal convoluted tubule cells
A prominent brush border of microvilli
What does the proximal convoluted tubule reabsorb
2/3 of the sodium and potassium
What is the histological difference between the thick and thin limb of the loop of Henle
Thin - simple squamous
Thick - cuboidal
How can you recognise the distal convoluted tubule
There’s no microvilli and therefore no prominent brush border
How does the distal convoluted tubule regulate acid base balance
It’s a secretes H+ and absorbs bicarbonate
How does the distal convoluted tubule regulate sodium
Exchanges sodium for potassium via aldosterone
What do the principle cells respond to
Aldosterone and ADH
How does ADH increase water reabsorption
Increases aquaporin 2 channels in the apical membrane