Urinary System Flashcards

(44 cards)

1
Q

What are the layers of the kidney

A

Cortex
Medulla
Pelvis

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2
Q

What is in the renal cortex

A

Glomeruli
PCT
DCT

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3
Q

What is a medullary ray

A

A collection of loop of Henle’s and collecting ducts that originate from the nephrons that have the renal corpuscle in the outer part of the cortex

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4
Q

Are there glomeruli in the renal medulla

A

No

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5
Q

What is the glomerulus supported by

A

Mesangial cells

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6
Q

What’s surrounds the glomerulus

A

Bowmans capsule

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7
Q

What is the basement membrane of the glomerulus lined by

A

Podocytes

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8
Q

What stain highlights the glomerular basement membrane

A

Periodic acid shciff

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9
Q

What do mesangial cells comprise

A

Smooth muscle

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10
Q

 Does albumin get filtrated out of the capillary lumen

A

No it’s too large

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11
Q

What is specific about the basement membrane of the glamorous

A

It’s a double basement membrane and it’s negatively charged

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12
Q

Where is the juxtaglomerular apparatus

A

Right next to the glomerulus

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13
Q

What do granular cells do

A

Detect blood pressure and secrete renin at low blood pressures

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14
Q

What does the juxtaglomerular apparatus contain

A

Granular cells and macula densa cells

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15
Q

What is glomerular tubular feedback

A

Where the macula densa cells detect sodium concentrations and feedback to the afferent arteriole

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16
Q

What is the proximal convoluted tubule lined by

A

Simple cuboidal epithelium

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17
Q

What is the border of proximal convoluted tubule cells

A

A prominent brush border of microvilli

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18
Q

What does the proximal convoluted tubule reabsorb

A

2/3 of the sodium and potassium

19
Q

What is the histological difference between the thick and thin limb of the loop of Henle

A

Thin - simple squamous

Thick - cuboidal

20
Q

How can you recognise the distal convoluted tubule

A

There’s no microvilli and therefore no prominent brush border

21
Q

How does the distal convoluted tubule regulate acid base balance

A

It’s a secretes H+ and absorbs bicarbonate

22
Q

How does the distal convoluted tubule regulate sodium

A

Exchanges sodium for potassium via aldosterone

23
Q

What do the principle cells respond to

A

Aldosterone and ADH

24
Q

How does ADH increase water reabsorption

A

Increases aquaporin 2 channels in the apical membrane

25
What do the intercalated cells do
Alpha cells secrete hydrogen ions and beta cells secrete by bicarbonate
26
What level does the renal artery come off the abdominal aorta
L1
27
What are the divisions of the renal artery
``` Anterior and Posterior Interlobar Arcuate Interlobular Afferent arteriole ```
28
What is the renal pelvis lined by
Urothelium
29
What does the renal pelvis do
Transports filtrate from nephron to ureter
30
What is urothelium
A stratified epithelium that can stretch in 3 dimensions
31
What cells are on the surface of urothelium
Umbrella cells
32
How do umbrella cells prevent the passage of urine between them
They have tight intercellular junctions
33
What is underneath the umbrella cells in the urothelium
Pseudostratified layer of polygonal cells
34
What are the layers of muscle in the ureters
Inner longitudinal and outer circular
35
What is the bladder lined by
Urothelium
36
What creates a functional valve in the bladder
The world to find muscularis propria which the Ureta has to pass through to get to the bladder
37
What is the proximal female urethra lined by
Transitional epithelium
38
What is the distal female urethra lined by
Squamous epithelium
39
What glands open to the female urethra
Paraurethral and periurethral
40
What are the parts of the male urethra
Prostatic urethra Membranous urethra Penile urethra
41
What is the prostatic urethra line by
Urothelium
42
What is the membranous urethra lined by
Urothelium
43
What is the proximal penile urethra lined by
Pseudostratified epithelium
44
What is the distal penile urethra lined by
Stratified squamous epithelium