urinary system Flashcards

(32 cards)

1
Q

what are the functions of the urinary system

A
  • Filter blood
  • Regulate blood volume
  • Regulate concentration of blood solutes
  • Regulate pH of extracellular fluid
  • Regulate blood cell synthesis
  • Synthesis in the active form of vitamin D
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2
Q

what is the external anatomy of the kidney

A

renal capsule, perirenal fat, renal fascia, hilum

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3
Q

what is the internal anatomy of the kidney

A

cortex, medulla, calyces, renal pelvis, ureter

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4
Q

what is the functional unit of the kidney

A

nephron

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5
Q

what are the parts of the nephron

A

i. Renal corpuscle
ii. Proximal convoluted tubule
iii. Loop of henle
iv. Distal convoluted tubule
v. Collecting ducts

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6
Q

What is the order of urine formation in the nephron?

A

Nephron, renal pelvis, ureters, urinary bladder, urethra

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7
Q

Name the 3 processes by which urine formation is categorized

A

1.golumlar Filtration
2.Tubular reabsorption
3.Tubular secretion

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8
Q

What is filtrate

A

it is the pre form of urine, but when it exists the body it is called urine

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9
Q
  1. Filtration pressure determines
A

the amount of filtrate formed

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10
Q

What is the glomerular filtration rate

A

The volume of filtrate formed by both kidneys per min

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11
Q

what is the bowmans capsule

A
  • Enlarged end of the nephron
  • Indented to form a double-walled chamber
  • Surround glomerulus
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12
Q

what is the glomerular capillary

A
  • Network of capillaries
  • Blood enters afferent arteriole
  • Exits efferent arteriole
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13
Q

what is a podocyte

A

these wrap around the glomerular capillaries

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14
Q

what is the main function of the juxtaglomerular apparatus

A

Releases renin which regulates blood pressure
- main site of renin production

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15
Q

Juxtaglomerular cells

A

ring of smooth muscle that lines the afferent arteriole entering bowmans capsule, Secretes renin which is important in regulation of blood pressure

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16
Q

Macular densa

A

specialized tubule cells of the distal convoluted tubule, responds to changes in the sodium chloride levels in the distal convoluted tubule

17
Q

Which part of the nephron is involved during tubular reabsorption

A

Peritubular capillaries

18
Q

Major site of reabsorption

A

proximal convoluted tubule

19
Q

How do solutes transport through the nephron during the reabsorption

A

Solutes are transported by active transport and co transport

20
Q

how is water get transported

A

through osmosis

21
Q

ascending loop of Henle in tubular reabsorption

A

impermeable to water but still permeable to solutes
- The water stays in the filtrate
- Not allowing water or solute to pass through

22
Q

descending loop of Henle in tubular reabsorption

A

water exits osmosis and solutes enter
- Permeable to water (squamous cells)
- Additional 15% of filtrate volume is reabsorbed

23
Q

How does diabetes impact filtrate volume? In other words, do diabetes patients produce higher volume of filtrate or lower volume of filtrate?

A
  • People with diabetes cannot reabsorb 100% of glucose because the concentration of glucose in the filtrate exceeds the capacity of transporters. Not enough transport proteins to take enough glucose back
  • Glucose in the filtrate draws water into the convoluted tubule which increases filtrate volumes
24
Q

What is tubular secretion

A

Solutes are secreted from the blood into the filtrate

25
where does tubular secretion take place in the nephron
distal convoluted tubule
26
Give examples on what types of solutes or substances can be secreted directly into filtrate?
Urea, creatinine, sulfates, phosphates and nitrates
27
Renin-angiotensin-aldosterone
Stimulated by _low_ blood pressure. Changes of the blood pressure will send signal to juxtaglomerular cells to secrete an enzyme _aldosterone_.
28
ADH
Stimulated by _decreased_ blood pressure or _increased_ blood osmolality.
29
What are the 2 common substances that can affect ADH release? What happens if ADH is blocked?
Caffeine and alcohol
30
glomerular filtration
movement of substances from the blood within the glomerelus into the capsular space
31
tubular reabsorption
32
tubular secretion