Urinary System Flashcards

0
Q

How much cardiac output do the kidneys (combined) recieve?

A

20-25%

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1
Q

Where are the kidneys located compared to the vertebrae?

A

Between T12 - L3

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2
Q

What are the coverings of the kidneys from superficial to deep?

A

Renal fascia, adipose capsule, renal capsule

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3
Q

What kind of tissue comprises the renal fascia?

A

Dense irregular CT

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4
Q

What are the internal layers of the kidney?

A

Cortical layer and medullary layer

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5
Q

Which layer contains a majority of the nephrons?

A

The cortical layer

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6
Q

How many nephrons does each kidney contain?

A

~1.25 million/kidney

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7
Q

Describe the flow of blood from the abdominal aorta to the glomerulus.

A

Abdominal aorta -> renal artery -> segmental (lobar) arteries -> interlobar arteries -> arcuate arteries -> cortical radiate (interlobular) arteries -> afferent arterioles -> glomerulus

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8
Q

What nerves innervate the kidneys, what kind of fibers are they, and where do they come from?

A

Renal nerves, which are primarily postganglionic sympathetic fibers from the superior mesenteric ganglion

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9
Q

What is the function of the renal corpuscle?

A

Filtration of blood, emptying into the tubule

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10
Q

What is the function of the tubular system?

A

Turning filtrate into urine

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11
Q

What are the two types of nephrons?

A

Cortical and juxtamedullary

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12
Q

What are the percentages of the two types of nephrons?

A

Cortical: 85%
Juxtamedullary: 15%

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13
Q

Where are cortical nephrons located?

A

Almost entirely in the cortex of the kidney; their loops of Henle dip slightly into the medulla

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14
Q

Where are juxtamedullary nephrons located?

A

They lie near the cortical-medullary junction; their loops of Henle deeply invade the medulla

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15
Q

What is the relative function of cortical nephrons?

A

Perform more of the reabsorptive and secretory functions

16
Q

What is the relative function of juxtamedullary nephrons? How do they achieve this?

A

Produce more concentrated urine due to longer loops of Henle

17
Q

What structure is contained in Bowman’s capsule, and what s the name of the space?

A

The glomerulus, and Bowman’s space

18
Q

What is the glomerulus?

A

A tuft of “leaky” capillaries

19
Q

The fenenstrations of the glomerular capillaries retain what things? What do they allow to leak out?

A

Blood cells and larger proteins are kept; water and other solutes are released into the glomerular filtrate.

20
Q

What are the histological layers of Bowman’s capsule and where are they?

A

Parietal, which surrounds the outer wall of the capsule; visceral, which covers the glomerular capillaries

21
Q

What tissue is capsular epithelium (parietal layer) comprised of?

A

Simple squamous epithelium

22
Q

What layers are deep to the glomerular epithelium?

A

Lamina densa (basement membrane) and glomerular endothelium

23
Q

What cells make up the glomerular epithelium (visceral layer)?

A

Podocytes

24
Q

What is the name of the processes of the glomerular epithelium? What are the openings called? What do they allow out?

A

Pedicels, which contain slit pores/filtration slits that allow the passage of dissolved ions and small organic molecules

25
Q

Where does the filtrate in Bowman’s space drain into?

A

Proximal convoluted tubule

26
Q

What is the lining of the PCT?

A

Simple cuboidal epithelium with microvilli