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Flashcards in Urinary_Brainscape Deck (29)
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1

Germ Layers that form the Urinary System

Intermediate Mesoderm & Endoderm

2

Position of Intermediate Mesoderm Differentiation

Retroperitoneal

3

Pronephroi (Where, When, Function?)

C5-C7, Wk 4, Non-functional, PRONEPHRIC DUCT

4

Mesonephroi (Where, When, Function)

T1-L3, Wk 4-10, Filter waste, Mesonephric Tubule-> Primordial Nephron, Mesonephric Duct

5

Metanephroi (Where, When, Function)

Pelvic Region, Wk 5/9-10, Definitive Kidney

6

Ureteric Bud

Epithelium from IM, Ureter, Renal Pelvis, Major/Minor Calyces, Collecting Ducts/Tubules

7

Metanephric Blastema

Mesenchyme from IM, Nephron (Bowman's Capsule, Prox. Conv. Tubule, Loop of Henle, Distal Conv. Tubule)

8

How does the definitive kidney form?

Recipricol Induction between the Ureteric Bud Epithelium and the Metanephric Mesenchyme

9

Explain the lobulations of the fetal kidneys

Nephrons meet the collecting ducts and grow at different rates, causing lobulations that smooth out after birth with further nephron growth (size, not #)

10

What causes the kidneys to ascend?

Growth of the sacral and lumbar regions of the body

11

How do the kidneys receive blood during ascent?

Transient arteries that form and degenerate

12

Function of the Urorectal Septum

Forms the perineal body while dividing the cloaca into the urogenital sinus and anorectal canal

13

The parts of the cloaca

Cranial/Vesical, Pelvic, Caudal/Phalic

14

Cranial/Vesical Cloaca becomes…

the Urinary bladder in both sexes

15

Pelvic part of the Cloaca becomes…

Membranous & Prostatic Urethra in Males; entire Urethra in Females

16

Caudal/Phalic part of Cloaca becomes…

part of the Penile Urethra in Males; Vestibule in Females

17

Trigone of the Bladder is derived from

Mesonephric Ducts (IM); Cranial proliferations causes caudal growth

18

Relation of Ureters to the Mesonephric ducts in the Trigone

Ureters are pulled cranial by the kidneys, Mesonephric ducts are pulled caudal by the testis

19

Bilateral Renal Agenisis

Incompatible with life, causes Oligohydramnios --> Potters Sequence

20

Unilateral Renal Agenesis

Compatible with life, asymptomatic

21

Autosomal Dominant PKD

Cysts grow in the kidneys later in life (30-40s) causing renal failure; transplants or dialysis possible

22

Autosomal Recessive PKD

Cysts grow in the kidneys in utero or within the first few years of life, usually fatal

23

Pelvic Kidney

Kidneys fail to ascend; Higher chance of urinary tract infections, otherwise asymptomatic

24

Horshoe Kidney

Metanephric Mesenchyme of both kidneys fuse caudally and get caught on the IMA during ascent; increased risk of Urinary tract infections

25

Accessory Renal Arteries

Transient arteries do not degenerate during ascent; Supply specific segment of kidney; damage to this artery will cause necrosis only to the specific region it supplied

26

Urachal Cyst

Asymptomatic until it becomes infected

27

Urachal Sinus

Usually a urachal cyst that forms an external opening to drain itself; may also be a diverticulum off the bladder

28

Urachal Fistula

Allows urine to pass from the bladder through the umbilicus

29

Extrophy of the Bladder/Cloaca

Failure of the ventral body wall to fuse completely ventral to the pelvic region; Cloacal Extrophy more serious; Impedes formation of the urinary and genital systems; may require surgical intervention if not fatal