Urolithiasis Flashcards

1
Q

Name some risk factors for urolith development

A

Urine supersaturation with calculogenic substances
Favorable urine pH
Reduced crystal inhibitors
Retention of crystals in urinary tract

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2
Q

Struvite uroliths occur in urine with _________pH

A

Alkaline

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3
Q

Can struvite be dissolved with nutritional and/or medical management?

A

Yes!

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4
Q

A female dog with a history of recurrent UTIs presents with LUT signs (pollakiuria, hematuria, stranguria). You want to rule out the presence of ________ stones, so you take radiographs.

A

Struvite

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5
Q

Key nutritional factors for prevention and dissolution of sterile struvite uroliths

A

Water!
Limit dietary precursors (Mg, protein, P)
Enhance NaCl (enhances water, keeps bladder flushed)
Acidify the urine!

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6
Q

T/F: A patient that presents with a UTI and struvite crystals should be placed on a dissolution diet long-term.

A

False - if this is the first episode, dissolution/prevention diets may NOT be needed

Treat the UTI

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7
Q

When do you stop a dissolution diet for struvite?

A

Continue diet 1 month after negative imaging

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8
Q

What component of cranberry extract may be helpful in managing chronic UTIs? Why?

A

Proanthocyanidins
Reduce microbial adherence to

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9
Q

Like proanthocyanidins, __________ reduces microbial adherence and can be used in patients with chronic, recurring UTIs

A

D-Mannose powder

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10
Q

Calcium oxalate uroliths form in _________ urine

A

Acidic

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11
Q

T/F: Calcium oxalate uroliths can be managed with dietary/medical management

A

No - require lithotripsy or cystotomy

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12
Q

How can calcium oxalate be PREVENTED nutritionally?

A
  • Limit dietary precursors (Ca, Oxalate)
  • Limit protein (Protein promotes urinary citrate excretion and citrate is beneficial againse Ca oxalate)
  • Enhance inhibitors (Citrate, Mg)
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13
Q

T/F: some breeds are predisposed to developing calcium oxalate uroliths

A

True - Mini schnauzers (calciuria) and others

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14
Q

Purine uroliths form in ________ urine

A

Acidic

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15
Q

Can purine uroliths be dissolved with nutritional and/or medical management?

A

Yes

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16
Q

What is the representative breed for purine uroliths? What is a common concurrent disease?

A

Yorkies
PSS

17
Q

Why can switching to a vegetarian diet limit purine uroliths?

A

Alkalinizes the urine by limiting high purine containing animal proteins

18
Q

T/F: Urate dissolution protocols are available for both dogs and cats

A

False - not available for cats

19
Q

How are cystine uroliths managed?

A

Similar to purine (low animal protein or vegetarian)
Potassium citrate

20
Q

Target urine pH for struvite prevention/dissolution

A

Dissolution: 5.9-6.1
Prevention: 6.0-6.5

21
Q

Target urine pH for Ca oxalate

A

6.5-8.0

22
Q

Target urine pH for urate and cystine

A

7.0-7.5

23
Q

Monitoring uroliths

A

BW, BCS, MCS
Appetite, behavior
Urine every 3-6 months
Culture
Radiographs (q2-4 weeks during dissolution of struvite, purine)