Valvular disease Flashcards

(71 cards)

1
Q

When should you repeat BP readings and what should you do if that criteria remains

A

Repeat measurements if difference in readings between arms in >15mmHg
If the difference in readings between arms remains more than 15 mmHg on the second measurement, measure subsequent blood pressures in the arm with the higher reading

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2
Q

Define malignant hypertension

A

BP ≥ 200/130 mmHg

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3
Q

What are the 3 stages of hypertension

A

Stage 1 Hypertension: 140/90 to 159/99 mmHg
Stage 2 Hypertension: 160/100 to 179/119 mmHg
Stage 3 Hypertension: sBP ≥ 180 mmHg or dBP ≥ 120 mmHg

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4
Q

Who should you offer ABPM to

A

People with clinic blood pressure of 140/90 mmHg or higher

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5
Q

What do you do to confirm hypertension (2 criteria)

A

clinic blood pressure of 140/90 mmHg or higher and

ABPM daytime average or HBPM average of 135/85 mmHg or higher

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6
Q

What are the investigations for target organ damage (8)

A
Proteinuria – estimation of albumin:creatinine ratio (ACR) + test haematuria 
Glycated haemoglobin (HbA1C)
Electrolytes 
Creatinine 
eGFR 
Total cholesterol and HDL cholesterol 
Fundi (hypertensive retinopathy) 
12-lead ECG
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7
Q

Endocrine causes of hypertension (8)

A

Diabetes, hyperthyroidism, Cushing’s, Conn’s, hyperparathyroidism, phaeochromocytoma, Congenital Adrenal Hyperplasia, Acromegaly

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8
Q

Renal causes of hypertension (5)

A

Renal artery stenosis
Chronic glomerulonephritis, pyelonephritis
Polycystic kidney disease
Renal failure

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9
Q

Cardio causes of hypertension (2)

A

Coarctation of the aortaIncreased intravascular volume

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10
Q

Drugs that cause hypertension (3)

A

Sympathomimetics, corticosteroids, oral contraceptives

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11
Q

Pregnancy cause of hypertension

A

Pre-eclampsia

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12
Q

Causes of hypertension due to raised instravascular volume (3)

A

heart failure, liver failure, nephrotic syndrome

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13
Q

What abnormal heart sounds can you hear in hypertension (2)

A

may hear loud S2, S4

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14
Q

Mx of hypertension (think of the populations, also there is 4 stages)

A
HT diabetes or under 55 and not black
ACEi or ARB
then
ACEi or ARB and CCB or thiazide-like diuretic
then
all all
Age 55 or black without diabetes
CCB
then
CCB + ARB/ACEi or thiazide-like diuretic
then all 4

Stage 4 os confirm resistant hypertension, seek help, or add spironolactone/alpha/beta blocker

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15
Q

Example of CCB (2)

A

Amlodipine

Verapamil

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16
Q

Common S.E. of ACEi (3)

A

Cough
High potassium
Increased creatinine

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17
Q

Common S.E. of CCBs (1)

A

Oedema

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18
Q

Common S.E. of BB (1)

A

Dizziness

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19
Q

Common S.E. of diuretics (3)

A

Dry mouth
Thirst
Low potassium levels

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20
Q

Common S.E. of alpha-blockers (1)

A

Dizziness

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21
Q

BP targets (clinic and home, for the two demographics)

A

<80 years
Clinic <140/90 mmHg
Home <135/85 mmHg

> 80 years
Clinic <150/90 mmHg
Home <145/85 mmHg

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22
Q

What is losartan

A

An AT2R antagonist

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23
Q

What causes the second heart sound

A

Thefirst heart sound(S1) is caused by the closing of theatrioventricular valves(thetricuspidandmitral valves) at the start of thesystolic contractionof theventricles

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24
Q

What causes normal physiological splitting of S2

A

inspiration lowers intrathoracic pressure, increasing the compliance of the pulmonary vascular bed, and augmenting right heart filling. Right ventricular systole is lengthened as a result, causing the pulmonic valve to close after the aortic valve, resulting in splitting of the second sound at 3LICS or 4LICS.

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25
What causes paradoxical splitting of S2 (2)
results from delayed onset or prolongation of left ventricular systole (Prolong LV emptying, AS, LBBB)
26
What causes normal, wide splitting of S1 (3)
Normal wide splitting S1 – RBBB, LV pacing, ectopic beats
27
What cause widened splitting of S2 (2)
prolong PV emptying – pulmonay stenosis, RBBB
28
What cause fixed splitting of S2
ASD
29
What is the cadence of the third heart sound
Kentucky
30
What is the cause of the third heart sound physically
S3 produced during passive rapid left ventricular filling when blood strikes a compliant left ventricle.
31
What does a third heart sound indicate
In older patients it can indicated heart failure, as the ventricles and chordae are stiff and weak so they reach their limit much faster than normal
32
What is the cadence of the fourth heart sound
Tennessee
33
What is the cause of the fourth heart sound physically
Results from a forceful atrial contraction during presystole that ejects blood into a hypertrophied ventricle which cannot expand further
34
What does a fourth heart indicate (3)
HTN, aortic stenosis, hypertrophic cardiomyopathy
35
Which pathology is accentuated on auscultation with the patient on the LHS
Mitral stenosis
36
Which pathology is accentuated on auscultation with the patient leaning forward
Aortic regurgitation
37
What is crescendo-decrescendo murmur also known as
Ejection systolic
38
What is ejection systolic murmur also known as
Crescendo-descrescendo
39
Clinical signs of aortic stenosis (4)
Crescendo decrescendo systolic murmur (radiate to carotids) Heaving apex beat Slow rising pulse
40
What does a narrow pulse pressure indicate
Aortic stenosis
41
What is seen on an ECG of aortic stenosis
Evidence of LVH
42
Where does mitral regurgitation radiate to
Left axilla
43
What does a mitral regurgitation murmur sound like
High pitched ‘whistling’ mumur
44
Mitral regurgitation - what during the heart beat is the abnormal heart sound?
Pan-systolic
45
What is mitral regurgitation associated with (4)
IHD Idiopathic weaknening of valve with age Connective tissue disorder e.g. EDS, MS
46
What does a mitral stenosis murmur sound like
Low pitched rumbling
47
When during the heart beat is the abnormal heart sound in mitral stenosis
Mid-diastolic
48
What heart sounds change in mitral stenosis
Loud S1 | Mid diastolic low pitched rumbling murmur
49
What pathology causes a loud S1/opening snap
Mitral stenosis
50
What is mitral stenosis associated with (3)
Often associated with Atrial Fibrilation Malar flush = Red cheeks Associated with rheumatic fever
51
Signs of aortic regurgitation (4)
Watson's water hammer pulse, also known as Corrigan's pulse or collapsing pulse Quincke's sign De Musset’s Sign Becker’s sign
52
What murmur is heard in aortic regurgitation, describe it and what is its name
Austin Flint | Mid-diastolic rumbling murmur
53
What is an Austin Flint murmur
Mid diastolic rumbling murmur of aortic regurgitation
54
What is Carvallos sign
Of tricuspid regurgitation, pansystolic murmur heard louder on inspiration
55
Clinical feature of tricuspid regurgitation
Elevated JVP with giant V waves
56
5 manifestations of rheumatic fever
Arthritis, Carditis(Carey Coombs murmur -mid-diastolic murmur due to mitral vasculitis, pericarditis, pericardial effusion or rub, etc), Sydenham’sChorea(+/-slurred speech), SC nodules, Erythema marginatum
57
What is a Graham Steel murmur associated with
Pulmonary regurgitation
58
How to differentiate AR and MS?
Wide PP in AR
59
Buzzwords - which valvular pathology: | narrow PP
Aortic stenosis – exertional syncope, SOB, angina
60
Buzzwords - which valvular pathology: | soft 2nd heart sound
Aortic stenosis – exertional syncope, SOB, angina
61
Buzzwords - which valvular pathology: | heaving apex beat
Aortic stenosis – exertional syncope, SOB, angina
62
Buzzwords - which valvular pathology: | blowing pansystolic murmur at apex
Mitral regurgitation
63
Buzzwords - which valvular pathology: | soft 1st heart sound
Mitral regurgitation
64
Buzzwords - which valvular pathology: | wide PP
Aortic regurgitation
65
Buzzwords - which valvular pathology: | end diastolic murmur at left sternal edge
Aortic regurgitation
66
Buzzwords - which valvular pathology: | murmur best heard leaning forward at expiration
Aortic regurgitation
67
Buzzwords - which valvular pathology: | rumbling mid-diastolic murmur at apex
Mitral stenosis
68
Buzzwords - which valvular pathology: | pansystolic murmur at left lower sternal edfe
Tricuspid regurgitation
69
Buzzwords - which valvular pathology: | IVDU
Tricuspid regurgitation
70
Buzzwords - which valvular pathology: | increased JVP
Tricuspid regurgitation
71
Buzzwords - which valvular pathology: | tapping apex beat
Mitral stenosis