Variation In Biochemistry And Cell Strucutre UNIT 2 Flashcards
Red blood cells contain…
Haemoglobin
Oxygen is carried round the body by
Haemoglobin
What is haemoglobin
Large protein with a quaternary structure, so made up of four polypeptide chains. Each chain has a haem group which contains iron and gives haemoglobin its red colour. Haemoglobin has a high affinity for oxygen, each molecule can carry four oxygen molecules. In the lungs oxygen join to haemoglobin in red blood cells to form oxyhemoglobin. Is a reversible reaction, when oxygen leaves oxyhemoglobin near the body cells it turns back into haemoglobin
What does affinity for oxygen mean
Tendency to combine with oxygen
Aswell as being found in all vertebrates haemoglobin is found in….
Earthworms, starfish, some insects and plants
Haemoglobin saturation depends on…..
The partial pressure of oxygen
What is the partial pressure of oxygen
A measure of oxygen concentration
The greater the conc of dissolved oxygen in cells, the higher the partial pressure
What is the partial pressure of carbon dioxide
Measure of conc of carbon dioxide in a cell
Oxygen combines with haemoglobin to form oxyhaemoglobin where there’s a high …..
Partial pressure of oxygen
When does oxyhaemogblon lose its oxygen
When there’s a lower partial pressure of oxygen
Why does oxygen enter blood capillaries at the alveoli in the lungs
Alveoli have a high partial pressure of oxygen, so oxygen combines with haemoglobin to form oxyhaemoglobin
When cells respire they use up oxygen which …..
Lowers the partial pressure of oxygen. Red blood cells deliver oxyhaemoglobin to respiring tissues , where it unloads oxygen
Haemoglobin returns to lungs to pick up more oxygen
What does a dissociation curve show
How saturated the haemoglobin is with oxygen at any given partial pressure
Haemoglobin gives up its oxygen more readily at ….
Higher partial pressures of carbon dioxide. Gets more oxygen to cells during activity
What is the Bohr effect
When cells respire they produce carbon dioxide which raises the partial pressure of carbon dioxide. This increases rate of oxygen unloading , the dissociation curve shifts down, curves more to the right. The saturation of blood is lower for a given partial pressure of oxygen, meaning more oxygen is being released to tissues for high respiration